WormBase Tree Display for Gene: WBGene00001103
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| WBGene00001103 | SMap | S_parent | Sequence | W09G12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | dsl-1 | Person_evidence | WBPerson220 | |||||
| Sequence_name | W09G12.4 | ||||||||
| Molecular_name | W09G12.4 | ||||||||
| W09G12.4.1 | |||||||||
| CE18343 | |||||||||
| Other_name | CELE_W09G12.4 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | dsl-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dsl | ||||||||
| Allele (22) | |||||||||
| Strain | WBStrain00002904 | ||||||||
| WBStrain00008055 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00034014 | ||||||||
| 00034015 | |||||||||
| 00034016 | |||||||||
| 00034017 | |||||||||
| 00034018 | |||||||||
| 00108253 | |||||||||
| 00108254 | |||||||||
| 00108255 | |||||||||
| 00108256 | |||||||||
| 00108257 | |||||||||
| Ortholog (31) | |||||||||
| Paralog | WBGene00002246 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00001104 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001105 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001107 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001108 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001109 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00023163 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes | ||||||
| WBGene00021525 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00021513 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | dsl-1 encodes a secreted protein with a single DSL and EGF domain inseries, resembling Delta/LAG-2; DSL-1, with APX-1 and LAG-2, iscollectively required for LIN-12/Notch-mediated lateral signalling duringpostembryonic vulval development; DSL-1, when misexpressed by lag-2sequences, can rescue the larval-lethal and anchor cell phenotypes oflag-2(q420ts); dsl-1(RNAi) animals have abnormal vulvae in a geneticbackground sensitized for lateral signalling defects; dsl-1(ok810)mutants, while viable and fertile, have a 4% penetrant defect in lateralsignaling, which exceeds 13% with apx-1 and lag-2 RNAi; dsl-1 is stronglytranscribed in P6.p cells; SUR-2 regulates dsl-1 along with apx-1 andlag-2; DSL-1 belongs to a nematode-specific family of Delta/LAG-2-likeproteins that includes DSL-2, -3, -5, -6, and -7. | Paper_evidence | WBPaper00006450 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 21 Aug 2006 00:00:00 | ||||||||
| Automated_description | Enables Notch binding activity. Predicted to be involved in cell fate specification. Predicted to be located in extracellular region and membrane. Expressed in several structures, including P6.paa; P6.pap; P6.ppa; P6.ppp; and vulval cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | W09G12.4 | |||||||
| Corresponding_transcript | W09G12.4.1 | ||||||||
| Associated_feature | WBsf651642 | ||||||||
| WBsf717130 | |||||||||
| WBsf717131 | |||||||||
| WBsf229751 | |||||||||
| Experimental_info | RNAi_result (14) | ||||||||
| Expr_pattern | Chronogram1782 | ||||||||
| Expr2842 | |||||||||
| Expr6863 | |||||||||
| Expr10275 | |||||||||
| Expr1023005 | |||||||||
| Expr1030703 | |||||||||
| Expr1158595 | |||||||||
| Expr2011105 | |||||||||
| Expr2029341 | |||||||||
| Drives_construct | WBCnstr00000065 | ||||||||
| WBCnstr00003420 | |||||||||
| WBCnstr00015222 | |||||||||
| WBCnstr00018944 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (129) | |||||||||
| Interaction (202) | |||||||||
| WBProcess | WBbiopr:00000072 | ||||||||
| Map_info | Map | IV | Position | -21.0913 | Error | 0.040765 | |||
| Positive | Positive_clone | W09G12 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00006450 | ||||||||
| WBPaper00006503 | |||||||||
| WBPaper00017594 | |||||||||
| WBPaper00025694 | |||||||||
| WBPaper00026053 | |||||||||
| WBPaper00026872 | |||||||||
| WBPaper00027253 | |||||||||
| WBPaper00027276 | |||||||||
| WBPaper00027316 | |||||||||
| WBPaper00032102 | |||||||||
| WBPaper00034675 | |||||||||
| WBPaper00035079 | |||||||||
| WBPaper00038282 | |||||||||
| WBPaper00039484 | |||||||||
| WBPaper00040714 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
