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WormBase Tree Display for Gene: WBGene00000840

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Name Class

WBGene00000840SMapS_parentSequenceZK856
IdentityVersion1
NameCGC_namecul-5Person_evidenceWBPerson1052
Sequence_nameZK856.1
Molecular_nameZK856.1
ZK856.1.1
CE41096
Other_nameCELE_ZK856.1Accession_evidenceNDBBX284605
Public_namecul-5
DB_infoDatabaseAceViewgene5K663
WormQTLgeneWBGene00000840
WormFluxgeneWBGene00000840
NDBlocus_tagCELE_ZK856.1
PanthergeneCAEEL|WormBase=WBGene00000840|UniProtKB=Q23639
familyPTHR11932
NCBIgene179413
RefSeqproteinNM_073215.8
SwissProtUniProtAccQ23639
TREEFAMTREEFAM_IDTF105874
UniProt_GCRPUniProtAccQ23639
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcul
Allele (48)
StrainWBStrain00001851
WBStrain00032168
RNASeq_FPKM (74)
GO_annotation00079158
00079159
00079160
00079161
00079162
00079163
00079164
00107887
00107888
Contained_in_operonCEOP5246
Ortholog (39)
ParalogWBGene00000836Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000837Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000838Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000839Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000841Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000143Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptioncul-5 encodes a cullin, orthologous to vasopressin-activated calcium-mobilizing receptor-1 in mammals, that is thought to regulate the cell cycle by virtue of its paralogy to cul-1 and cul-2; however, CUL-5 is dispensable for viability and gross morphology in mass RNAi screens, and does not appear to interact with any of 17 Skp1-related proteins (SKR-1 through SKR-21).Paper_evidenceWBPaper00002473
WBPaper00005128
WBPaper00005654
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable protein-macromolecule adaptor activity and ubiquitin protein ligase binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to be part of Cul5-RING ubiquitin ligase complex and SCF ubiquitin ligase complex. Expressed in several structures, including head; intestine; nervous system; tail; and vulval muscle. Is an ortholog of human CUL5 (cullin 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK856.1
Corresponding_CDS_historyZK856.1:wp175
Corresponding_transcriptZK856.1.1
Other_sequence (34)
Associated_featureWBsf647140
WBsf661616
WBsf1001071
Experimental_infoRNAi_result (20)
Expr_patternChronogram1562
Expr7264
Expr8294
Expr1024104
Expr1030522
Expr1163196
Expr2010590
Expr2028830
Drives_constructWBCnstr00002643
WBCnstr00037253
Construct_productWBCnstr00037253
Microarray_results (18)
Expression_cluster (112)
Interaction (34)
Map_infoMapVPosition2.30976Error0.009953
PositivePositive_cloneZK856Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5581
Pseudo_map_position
Reference (13)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene