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WormBase Tree Display for Gene: WBGene00000840

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Name Class

WBGene00000840SMapS_parentSequenceZK856
IdentityVersion1
NameCGC_namecul-5Person_evidenceWBPerson1052
Sequence_nameZK856.1
Molecular_nameZK856.1
ZK856.1.1
CE41096
Other_nameCELE_ZK856.1Accession_evidenceNDBBX284605
Public_namecul-5
DB_infoDatabaseAceViewgene5K663
WormQTLgeneWBGene00000840
WormFluxgeneWBGene00000840
NDBlocus_tagCELE_ZK856.1
PanthergeneCAEEL|WormBase=WBGene00000840|UniProtKB=Q23639
familyPTHR11932
NCBIgene179413
RefSeqproteinNM_073215.8
SwissProtUniProtAccQ23639
TREEFAMTREEFAM_IDTF105874
UniProt_GCRPUniProtAccQ23639
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcul
Allele (48)
StrainWBStrain00001851
WBStrain00032168
RNASeq_FPKM (74)
GO_annotation00079158
00079159
00079160
00079161
00079162
00079163
00079164
00107887
00107888
Contained_in_operonCEOP5246
Ortholog (39)
ParalogWBGene00000836Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000837Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000838Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000839Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000841Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000143Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptioncul-5 encodes a cullin, orthologous to vasopressin-activated calcium-mobilizing receptor-1 in mammals, that is thought to regulate the cell cycle by virtue of its paralogy to cul-1 and cul-2; however, CUL-5 is dispensable for viability and gross morphology in mass RNAi screens, and does not appear to interact with any of 17 Skp1-related proteins (SKR-1 through SKR-21).Paper_evidenceWBPaper00002473
WBPaper00005128
WBPaper00005654
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable protein-macromolecule adaptor activity and ubiquitin protein ligase binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to be part of Cul5-RING ubiquitin ligase complex and SCF ubiquitin ligase complex. Expressed in several structures, including head; intestine; nervous system; tail; and vulval muscle. Is an ortholog of human CUL5 (cullin 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK856.1
Corresponding_CDS_historyZK856.1:wp175
Corresponding_transcriptZK856.1.1
Other_sequence (34)
Associated_featureWBsf647140
WBsf661616
WBsf1001071
Experimental_infoRNAi_result (20)
Expr_patternChronogram1562
Expr7264
Expr8294
Expr1024104
Expr1030522
Expr1163196
Expr2010590
Expr2028830
Drives_constructWBCnstr00002643
WBCnstr00037253
Construct_productWBCnstr00037253
Microarray_results (18)
Expression_cluster (112)
InteractionWBInteraction000009242
WBInteraction000009243
WBInteraction000009245
WBInteraction000009247
WBInteraction000009249
WBInteraction000009250
WBInteraction000009251
WBInteraction000009252
WBInteraction000029178
WBInteraction000050833
WBInteraction000115618
WBInteraction000158023
WBInteraction000158025
WBInteraction000159224
WBInteraction000161047
WBInteraction000169128
WBInteraction000172998
WBInteraction000173003
WBInteraction000173005
WBInteraction000173006
WBInteraction000173009
WBInteraction000173011
WBInteraction000173015
WBInteraction000233525
WBInteraction000324414
WBInteraction000405463
WBInteraction000418534
WBInteraction000438403
WBInteraction000445794
WBInteraction000460711
WBInteraction000502741
WBInteraction000540886
WBInteraction000540903
WBInteraction000562624
Map_infoMapVPosition2.30976Error0.009953
PositivePositive_cloneZK856Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5581
Pseudo_map_position
Reference (13)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene