WormBase Tree Display for Gene: WBGene00000190

WBGene00000190 SMap: S_parent: Sequence: F45E4
  Identity: Version: 3
    Name: CGC_name: warf-1 Laboratory_evidence: GNW
      Sequence_name: F45E4.1
      Molecular_name: F45E4.1
        F45E4.1.1
        CE10492
      Other_name: arl-6 CGC_data_submission
        arf-1.1
        CELE_F45E4.1 Accession_evidence: NDB BX284604
      Public_name: warf-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 05 Nov 2004 15:32:14 WBPerson2970 Name_change: CGC_name: arf-1.1
        3 10 Sep 2020 13:38:11 WBPerson1983 Name_change: CGC_name: warf-1
                Other_name: arf-1.1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: warf
    Allele (19)
    RNASeq_FPKM (74)
    GO_annotation (15)
    Ortholog (54)
    Paralog (15)
    Structured_description: Automated_description: Predicted to enable GTP binding activity and GTPase activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in plasma membrane. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F45E4.1
    Corresponding_transcript: F45E4.1.1
    Other_sequence: CJC17359_1
      Oden_isotig24491
      Acan_isotig13284
      Oden_isotig05273
      Oden_isotig05276
    Associated_feature: WBsf228559
  Experimental_info: RNAi_result (14)
    Expr_pattern: Expr1014825
      Expr1151246
      Expr2009390
      Expr2027626
    Drives_construct: WBCnstr00037674
    Construct_product: WBCnstr00037674
    Microarray_results (21)
    Expression_cluster: WBPaper00005432:xbp-1(zc12)_downregulated
      WBPaper00032022:X-Ray_upregulated
      WBPaper00032479:CB4856vsN2_LifeStageProfile_Variation
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037682:sma-2_upregulated
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038168:lin-35_upregulated
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040285:H2S_24hr_downregulated
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044030:nhr-8(hd117)_upregulated
      WBPaper00044316:CH3HgCl_2.0uM_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044857:BAR-1_upregulated
      WBPaper00045257:bar-1(ga80)_upregulated
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045521:Spermatogenic
      WBPaper00045971:tunicamycin_upregulated_control
      WBPaper00045971:tunicamycin_upregulated_RtcB(null)
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00048923:Aging_regulated
      WBPaper00049018:ham-3(RNAi)_downregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00049954:BPA_upregulated
      WBPaper00049954:BPS_upregulated
      WBPaper00050121:mir-60(n4947)_upregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050504:hrp-2(RNAi)_upregulated
      WBPaper00050712:RC301_vs_DA650_4h-PA_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_specific
      WBPaper00051305:vit-2(ac3)_upregulated
      WBPaper00051338:jmjd-5(tm3735)_upregulated_G0
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sid-3(ok973)_upregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(ot267)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_upregulated_ClassI
      WBPaper00053321:embryo-to-L1_upregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053599:oocyte_vs_mitosis_upregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053771:up_at_24h-NaCl
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054191:H3.3(null)_L1_downregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00054810:deoxynivalenol_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055827:pfd-6(gk493446)_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:atfs-1(gk3094)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_adult
      WBPaper00056169:rrf-3(pk1426)_upregulated_L3
      WBPaper00056169:rrf-3(pk1426)_upregulated_L4
      WBPaper00056284:ints-5(RNAi)_upregulated
      WBPaper00056284:ints-6(t1903)_upregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00057196:raga-1(ok386)_downregulated)
      WBPaper00057265:metaformin_downregulated_OP50
      WBPaper00057265:metaformin_downregulated_OP50-MR
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057347:nhr-14(tm1473)_upreglated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059117:B.subtilis_downregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059373:stt-3(RNAi)_upregulated
      WBPaper00059426:Ag-nanoparticles_upregulated
      WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_downregulated_N2
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059735:glucose_downregulated_lpin-1(RNAi)
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059754:P.aeruginosa_PA14_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:CoCl2_6hr_upregulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060634:fhod-1(tm2363)_downregulated
      WBPaper00060634:unc-120(st364)_downregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(et18)_upregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00060911:prx-5(RNAi)_upregulated_protein
      WBPaper00060921:cat-2(e1112)_downregulated
      WBPaper00060951:metr-1(os521)_upregulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:M.braciatum_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061081:skpo-1(ok1640)_upregulated_OG1RF
      WBPaper00061340:hmc_homolog
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061409:neuronal-fzo-1(RNAi)_upregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:C10C5.2-Y58A7A.3
      WBPaper00061651:PHA_enriched
      WBPaper00061653:alh-4(hj221)_upregulated
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061853:osm-3(dh441)_upregulated
      WBPaper00061853:osm-3(dh441)_upregulated_tunicamycin
      WBPaper00061853:tunicamycin_downregulated_N2
      WBPaper00061902:camt-1(ok515)_regulated_AFD
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062078:NMR-HspB1_regulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062184:PA14_upregulated
      WBPaper00062193:daf-16(RNAi)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062440:crh-1(n3315)_upregulated
      WBPaper00062440:crh-1(syb385)_upregulated
      WBPaper00062456:doxycycline_upregulated_N2_protein
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00062672:let-418(n3536)_upregulated
      WBPaper00062684:pathogen_downregulated_N2
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064315:mes-3(bn199)_upregulated_EGCs
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064494:postdauer_downregulated_AWA
      WBPaper00064494:postdauer_downregulated_WholeAnimal
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00064788:ketamine_downregulated
      WBPaper00064789:Day6_vs_Day1_downregulated_neuron
      WBPaper00064789:Day9_vs_Day1_downregulated_neuron
      WBPaper00064789:Day12_vs_Day1_downregulated_neuron
      WBPaper00064999:miR-229-64-65-66_upregulated
      WBPaper00065029:cadmium_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065132:asna-1(ok938)_upregulated_protein
      WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
      WBPaper00065272:dhgd-1(tm6671)_upregulated
      WBPaper00065288:mdt-15(tm2182)_upregulated
      WBPaper00065392:Lb.reuteri_downregulated
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065749:Heat-Shock-With-Recovery_upregulated_N2
      WBPaper00065841:1_0
      WBPaper00065841:13_0
      WBPaper00065841:25_1
      WBPaper00065841:57_0
      WBPaper00065995:M.humicola-extract_upregulated_old-1(ok1273)
      WBPaper00066038:mip-1(how5)_downregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066118:cyclobutrifluram_downregulated
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4489_group_16
      WBPaper00025099:MA_specific
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00027111:rde-3(ne298)_upregulated
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_depleted
      WBPaper00031850:mdt-15(RNAi)_upregulated
      WBPaper00032062:age_regulated_genes
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00032948:FedUp
      WBPaper00034661:AgNPs_upregulated
      WBPaper00035227:heat_shock_regulated
      WBPaper00035873:osm-7_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035873:osm-11_regulated
      WBPaper00035873:osmotically_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_F
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00037113:CPF_16C_up-regulated
      WBPaper00037113:CPF_DZN_16C_up-regulated
      WBPaper00037113:DZN_16C_up-regulated
      WBPaper00040210:Chlorpyrifos_16C_regulated
      WBPaper00040210:Chlorpyrifos_24C_regulated
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.5
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040963:Q100_up
      WBPaper00040963:Q200_up
      WBPaper00040963:TA100_up
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041207:CE_dauer_up
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041906:I-3690_vs_I-4317_OP50_3d
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042067:Cu2+_upregulated_WT
      WBPaper00042204:Comamonas_DA1877_upregulated
      WBPaper00042236:flcn-1(ok975)_upregulated
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00042258:DA1877_upregulated_YoungAdult
      WBPaper00042574:JU1580_OrsayVirus_upregulated
      WBPaper00044013:nasp-1_downregulated
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00044091:Bpseudomallei_induced_12h
      WBPaper00044535:male_upregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00046083:oga-1(ok1207)_OP50_upregulated
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047070:DAF-16-dependent_UV_response
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00049538:atfs-1(et18)_upregulated
      WBPaper00050515:nipi-3(fr4)_upregulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc6390]:Cluster_D
      [cgc6390]:male_sex-enriched
    Interaction (13)
    WBProcess: WBbiopr:00000120
  Map_info: Map: IV Position: 3.36784 Error: 0.000898
    Positive: Positive_clone: F45E4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (15)
  Remark: This gene was previously known as the CGC approved name arl-6. arl-6 has now been re-assigned to WBGene000193. Curator_confirmed: WBPerson2970
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene