[C.elegansII] pk18 : deletion derived from pk30tci, increased sensitivity to colchicine and to chloroquine; gross phenotype WT. Cloned: encodes 1254 aa P-glycoprotein, 61-65% identical to mammalian P-glycoproteins. Transcripts present throughout development; pgp-1:lacZ expressed in intestine, throughout development. Tagged PGP-3 detected in apical membranes of gut and of excretory cell. [Broeks et al. 1995; NL]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.