WormBase Tree Display for Gene: WBGene00004003
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| WBGene00004003 | SMap | S_parent | Sequence | CHROMOSOME_V | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | pgp-9 | Person_evidence | WBPerson490 | |||||
| Sequence_name | C47A10.1 | ||||||||
| Molecular_name | C47A10.1 | ||||||||
| C47A10.1.1 | |||||||||
| CE15714 | |||||||||
| Other_name | CELE_C47A10.1 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | pgp-9 | ||||||||
| DB_info | Database | AceView | gene | 5S243 | |||||
| WormQTL | gene | WBGene00004003 | |||||||
| WormFlux | gene | WBGene00004003 | |||||||
| NDB | locus_tag | CELE_C47A10.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004003|UniProtKB=G5EG58 | |||||||
| family | PTHR24221 | ||||||||
| NCBI | gene | 180165 | |||||||
| RefSeq | protein | NM_075086.6 | |||||||
| TrEMBL | UniProtAcc | G5EG58 | |||||||
| UniProt_GCRP | UniProtAcc | G5EG58 | |||||||
| OMIM | gene | 171050 | |||||||
| 171060 | |||||||||
| 603201 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pgp | ||||||||
| Allele (249) | |||||||||
| Strain | WBStrain00003585 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (65) | |||||||||
| Paralog (23) | |||||||||
| Structured_description | Concise_description | pgp-9 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-9 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, and loss of pgp-9 activity via RNAi can result in embryonic lethality; pgp-9 promoter-gfp fusion proteins are expressed in the pharynx (first and second bulbs) and in the intestine. | Paper_evidence | WBPaper00004651 | |||||
| WBPaper00006421 | |||||||||
| WBPaper00006525 | |||||||||
| WBPaper00024561 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 07 Mar 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of human ABCB1 (ATP binding cassette subfamily B member 1); ABCB4 (ATP binding cassette subfamily B member 4); and ABCB5 (ATP binding cassette subfamily B member 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (41) | ||||||||
| Molecular_info | Corresponding_CDS | C47A10.1 | |||||||
| Corresponding_transcript | C47A10.1.1 | ||||||||
| Other_sequence (50) | |||||||||
| Associated_feature | WBsf982069 | ||||||||
| WBsf1002739 | |||||||||
| WBsf1021340 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00077359 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00070085 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042636 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00012052 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001328 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00022567 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1652 | ||||||||
| Expr3340 | |||||||||
| Expr5518 | |||||||||
| Expr5519 | |||||||||
| Expr1024605 | |||||||||
| Expr1031915 | |||||||||
| Expr1146620 | |||||||||
| Expr2014876 | |||||||||
| Expr2033111 | |||||||||
| Drives_construct | WBCnstr00002006 | ||||||||
| WBCnstr00002007 | |||||||||
| WBCnstr00004037 | |||||||||
| WBCnstr00011336 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (251) | |||||||||
| Interaction (24) | |||||||||
| Map_info | Map | V | Position | 13.1928 | Error | 0.00649 | |||
| Positive | Positive_clone | C47A10 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5600 | |||||||
| 4301 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00006402 | ||||||||
| WBPaper00006421 | |||||||||
| WBPaper00028970 | |||||||||
| WBPaper00031484 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00046184 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061262 | |||||||||
| WBPaper00062515 | |||||||||
| WBPaper00065331 | |||||||||
| Remark | Sequence connection from [Sheps JA, Baillie DL] [040902 ck1] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
