WormBase Tree Display for Gene: WBGene00001815
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| WBGene00001815 | SMap | S_parent | Sequence | W09D6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | hmt-1 | Person_evidence | WBPerson583 | |||||
| WBPerson36 | |||||||||
| WBPerson4191 | |||||||||
| Sequence_name | W09D6.6 | ||||||||
| Molecular_name | W09D6.6 | ||||||||
| W09D6.6.1 | |||||||||
| CE31731 | |||||||||
| Other_name | haf-5 | Person_evidence | WBPerson583 | ||||||
| WBPerson36 | |||||||||
| WBPerson4191 | |||||||||
| CELE_W09D6.6 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | hmt-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 10 Dec 2004 17:13:40 | WBPerson2970 | Name_change | CGC_name | hmt-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hmt | ||||||||
| Allele (127) | |||||||||
| Strain | WBStrain00001122 | ||||||||
| WBStrain00001123 | |||||||||
| WBStrain00035619 | |||||||||
| WBStrain00035648 | |||||||||
| WBStrain00039998 | |||||||||
| WBStrain00039999 | |||||||||
| WBStrain00040000 | |||||||||
| WBStrain00040001 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (33) | |||||||||
| Contained_in_operon | CEOP3884 | ||||||||
| Ortholog (40) | |||||||||
| Paralog (23) | |||||||||
| Structured_description | Concise_description | hmt-1 encodes a predicted transmembrane half-molecule ATP-binding cassette (ABC) transporter orthologous to Schizosaccharomyces pombe heavy metal tolerance factor 1 (SpHMT1), an ATP-dependent phytochelatin transporter; HMT-1 is required for cadmium detoxification and by homology, is predicted to promote sequestration of heavy metal-containing phytochelatins into intracellular vacuoles to protect cells from potential damage. | Paper_evidence | WBPaper00004424 | |||||
| WBPaper00025092 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 16 Jul 2007 00:00:00 | ||||||||
| Automated_description | Enables cadmium ion transmembrane transporter activity. Involved in cadmium ion transmembrane transport; cellular detoxification of cadmium ion; and detoxification of copper ion. Located in endosome and vacuolar membrane. Expressed in coelomocyte; head neurons; intestinal cell; and tail neurons. Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Is an ortholog of human ABCB6 (ATP binding cassette subfamily B member 6 (Langereis blood group)). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0060304 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:47) | ||||
| EFO:MONDO:0000170 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:47) | ||||||
| Molecular_info | Corresponding_CDS | W09D6.6 | |||||||
| Corresponding_CDS_history | W09D6.6:wp59 | ||||||||
| W09D6.6:wp84 | |||||||||
| Corresponding_transcript | W09D6.6.1 | ||||||||
| Other_sequence (46) | |||||||||
| Associated_feature | WBsf994264 | ||||||||
| WBsf994265 | |||||||||
| WBsf994266 | |||||||||
| WBsf994267 | |||||||||
| WBsf994268 | |||||||||
| WBsf1015925 | |||||||||
| WBsf227543 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00078484 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00006067 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00036408 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078227 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078228 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00055049 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061908 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (13) | |||||||||
| Drives_construct | WBCnstr00002005 | ||||||||
| WBCnstr00002030 | |||||||||
| WBCnstr00006912 | |||||||||
| WBCnstr00007020 | |||||||||
| WBCnstr00011352 | |||||||||
| WBCnstr00013806 | |||||||||
| Construct_product | WBCnstr00013806 | ||||||||
| WBCnstr00016459 | |||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (122) | |||||||||
| Interaction (12) | |||||||||
| WBProcess | WBbiopr:00000065 | ||||||||
| WBbiopr:00000096 | |||||||||
| Map_info | Map | III | Position | 5.95263 | Error | 0.021609 | |||
| Positive | Positive_clone | W09D6 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4392 | |||||||
| 4943 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (16) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
