WormBase Tree Display for Gene: WBGene00001815
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WBGene00001815 | SMap | S_parent | Sequence | W09D6 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | hmt | ||||||
Allele (127) | |||||||
Strain | WBStrain00001122 | ||||||
WBStrain00001123 | |||||||
WBStrain00035619 | |||||||
WBStrain00035648 | |||||||
WBStrain00039998 | |||||||
WBStrain00039999 | |||||||
WBStrain00040000 | |||||||
WBStrain00040001 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (33) | |||||||
Contained_in_operon | CEOP3884 | ||||||
Ortholog (40) | |||||||
Paralog (23) | |||||||
Structured_description | Concise_description | hmt-1 encodes a predicted transmembrane half-molecule ATP-binding cassette (ABC) transporter orthologous to Schizosaccharomyces pombe heavy metal tolerance factor 1 (SpHMT1), an ATP-dependent phytochelatin transporter; HMT-1 is required for cadmium detoxification and by homology, is predicted to promote sequestration of heavy metal-containing phytochelatins into intracellular vacuoles to protect cells from potential damage. | Paper_evidence | WBPaper00004424 | |||
WBPaper00025092 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 16 Jul 2007 00:00:00 | ||||||
Automated_description | Enables cadmium ion transmembrane transporter activity. Involved in cadmium ion transmembrane transport; cellular detoxification of cadmium ion; and detoxification of copper ion. Located in endosome and vacuolar membrane. Expressed in coelomocyte; head neurons; intestinal cell; and tail neurons. Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Is an ortholog of human ABCB6 (ATP binding cassette subfamily B member 6 (Langereis blood group)). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0060304 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:47) | ||
EFO:MONDO:0000170 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:47) | ||||
Molecular_info | Corresponding_CDS | W09D6.6 | |||||
Corresponding_CDS_history | W09D6.6:wp59 | ||||||
W09D6.6:wp84 | |||||||
Corresponding_transcript | W09D6.6.1 | ||||||
Other_sequence (46) | |||||||
Associated_feature | WBsf994264 | ||||||
WBsf994265 | |||||||
WBsf994266 | |||||||
WBsf994267 | |||||||
WBsf994268 | |||||||
WBsf1015925 | |||||||
WBsf227543 | |||||||
Experimental_info | RNAi_result | WBRNAi00078484 | Inferred_automatically | RNAi_primary | |||
WBRNAi00006067 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00036408 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00078227 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00078228 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00055049 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00061908 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (13) | |||||||
Drives_construct | WBCnstr00002005 | ||||||
WBCnstr00002030 | |||||||
WBCnstr00006912 | |||||||
WBCnstr00007020 | |||||||
WBCnstr00011352 | |||||||
WBCnstr00013806 | |||||||
Construct_product | WBCnstr00013806 | ||||||
WBCnstr00016459 | |||||||
Microarray_results (22) | |||||||
Expression_cluster (122) | |||||||
Interaction (12) | |||||||
WBProcess | WBbiopr:00000065 | ||||||
WBbiopr:00000096 | |||||||
Map_info | Map | III | Position | 5.95263 | Error | 0.021609 | |
Positive | Positive_clone | W09D6 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4392 | |||||
4943 | |||||||
Pseudo_map_position | |||||||
Reference (16) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |