glr-4 encodes a putative non-NMDA ionotropic glutamate receptor subunit,most closely related to GLR-3 and less so to GLR-7, possibly of thekainate subfamily; glr-4 is expressed in various sensory neurons andinterneurons from embyrogenesis onward; glr-4 expression requires UNC-42,as well as CFI-1 in URA cells.
Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to be located in postsynaptic density membrane. Expressed in cholinergic neurons and head neurons. Is an ortholog of human GRIK4 (glutamate ionotropic receptor kainate type subunit 4).
Sequence connection based on email from [Petcherski A] krb 02/04/05
Note that C06A8.10 was merged into the C06A8.9 gene prediction. 02/06/11 krb.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.