WormBase Tree Display for Gene: WBGene00003774
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| WBGene00003774 | SMap | S_parent | Sequence | F07F6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | nmr-1 | Person_evidence | WBPerson404 | |||||
| Sequence_name | F07F6.6 | ||||||||
| Molecular_name (3) | |||||||||
| Other_name | F56D1.b | Curator_confirmed | WBPerson1983 | ||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| F56D1.c | Curator_confirmed | WBPerson1983 | |||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_F07F6.6 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | nmr-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nmr | ||||||||
| Allele (99) | |||||||||
| Strain | WBStrain00040167 | ||||||||
| WBStrain00002755 | |||||||||
| WBStrain00040168 | |||||||||
| WBStrain00040666 | |||||||||
| WBStrain00040171 | |||||||||
| WBStrain00040796 | |||||||||
| WBStrain00054658 | |||||||||
| WBStrain00054659 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (32) | |||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00001612 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00001613 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001614 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001615 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001616 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001617 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001618 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001619 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00003775 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00012190 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | nmr-1 encodes an NMDA-type ionotropic glutamate receptor subunit that affects the duration of forward movement which is important during foraging behavior, and also affects osmotic avoidance; the slow kinetics typical of NMDA-dependent currents are likely important for its effect on forward movement. | Paper_evidence (2) | ||||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 04 Mar 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable ligand-gated monoatomic ion channel activity and signaling receptor activity. Predicted to contribute to NMDA glutamate receptor activity. Involved in locomotory behavior and regulation of forward locomotion. Located in neuron projection; plasma membrane; and synapse. Expressed in several structures, including ganglia; gonadal sheath cell; head mesodermal cell; nerve ring neurons; and oocyte. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; alcohol use disorder; autosomal dominant intellectual developmental disorder 8; and developmental and epileptic encephalopathy 101. Is an ortholog of human GRIN1 (glutamate ionotropic receptor NMDA type subunit 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:1289 | Homo sapiens | Paper_evidence | WBPaper00057034 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 30 Mar 2021 00:00:00 | ||||||||
| Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | |||||
| DOID:0070038 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||||||
| DOID:8725 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||||||
| DOID:0070387 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||||||
| DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||||||
| DOID:1574 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||||||
| DOID:11206 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4584) | ||||||
| Models_disease_asserted | WBDOannot00000907 | ||||||||
| WBDOannot00000908 | |||||||||
| Molecular_info | Corresponding_CDS | F07F6.6 | |||||||
| Corresponding_transcript | F07F6.6.1 | ||||||||
| Other_sequence | Oden_isotig22559 | ||||||||
| JI250035.1 | |||||||||
| Tcol_isotig18961 | |||||||||
| Associated_feature | WBsf987884 | ||||||||
| WBsf987885 | |||||||||
| WBsf1012228 | |||||||||
| WBsf1012229 | |||||||||
| WBsf223054 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00022320 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00043920 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030612 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (11) | |||||||||
| Drives_construct (42) | |||||||||
| Construct_product | WBCnstr00000022 | ||||||||
| WBCnstr00006168 | |||||||||
| WBCnstr00010811 | |||||||||
| WBCnstr00011656 | |||||||||
| WBCnstr00013203 | |||||||||
| WBCnstr00035874 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (94) | |||||||||
| Interaction | WBInteraction000004086 | ||||||||
| WBInteraction000004967 | |||||||||
| WBInteraction000005412 | |||||||||
| WBInteraction000005443 | |||||||||
| WBInteraction000029721 | |||||||||
| WBInteraction000118234 | |||||||||
| WBInteraction000122670 | |||||||||
| WBInteraction000122672 | |||||||||
| WBInteraction000157332 | |||||||||
| WBInteraction000157345 | |||||||||
| WBInteraction000166136 | |||||||||
| WBInteraction000169507 | |||||||||
| WBInteraction000169508 | |||||||||
| WBInteraction000169509 | |||||||||
| WBInteraction000169510 | |||||||||
| WBInteraction000169511 | |||||||||
| WBInteraction000169512 | |||||||||
| WBInteraction000169513 | |||||||||
| WBInteraction000169514 | |||||||||
| WBInteraction000169515 | |||||||||
| WBInteraction000169516 | |||||||||
| WBInteraction000169517 | |||||||||
| WBInteraction000169518 | |||||||||
| WBInteraction000169519 | |||||||||
| WBInteraction000169520 | |||||||||
| WBInteraction000169521 | |||||||||
| WBInteraction000169522 | |||||||||
| WBInteraction000169576 | |||||||||
| WBInteraction000169625 | |||||||||
| WBInteraction000170025 | |||||||||
| WBInteraction000173577 | |||||||||
| WBInteraction000173578 | |||||||||
| WBInteraction000173579 | |||||||||
| WBInteraction000181498 | |||||||||
| WBInteraction000215890 | |||||||||
| WBInteraction000239948 | |||||||||
| WBInteraction000243252 | |||||||||
| WBInteraction000244944 | |||||||||
| WBInteraction000245556 | |||||||||
| WBInteraction000260103 | |||||||||
| WBInteraction000263654 | |||||||||
| WBInteraction000267156 | |||||||||
| WBInteraction000267761 | |||||||||
| WBInteraction000273195 | |||||||||
| WBInteraction000273950 | |||||||||
| WBInteraction000275083 | |||||||||
| WBInteraction000279885 | |||||||||
| WBInteraction000287930 | |||||||||
| WBInteraction000290075 | |||||||||
| WBInteraction000296037 | |||||||||
| WBInteraction000313072 | |||||||||
| WBInteraction000317818 | |||||||||
| WBInteraction000323459 | |||||||||
| WBInteraction000330296 | |||||||||
| WBInteraction000336657 | |||||||||
| WBInteraction000358272 | |||||||||
| WBInteraction000377831 | |||||||||
| WBInteraction000386565 | |||||||||
| WBInteraction000395476 | |||||||||
| WBInteraction000414972 | |||||||||
| WBInteraction000427902 | |||||||||
| WBInteraction000445049 | |||||||||
| WBInteraction000464261 | |||||||||
| WBInteraction000467318 | |||||||||
| WBInteraction000467319 | |||||||||
| WBInteraction000469981 | |||||||||
| WBInteraction000471375 | |||||||||
| WBInteraction000501705 | |||||||||
| WBInteraction000501779 | |||||||||
| WBInteraction000502225 | |||||||||
| WBInteraction000556050 | |||||||||
| Map_info | Map | II | Position | -1.52008 | Error | 0.016815 | |||
| Positive | Positive_clone | F07F6 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4253 | |||||||
| 4538 | |||||||||
| 5279 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (105) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
