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WormBase Tree Display for Gene: WBGene00004345

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Name Class

WBGene00004345SMapS_parentSequenceCHROMOSOME_X
IdentityVersion1
NameCGC_namergs-2Person_evidenceWBPerson330
Sequence_nameF16H9.1
Molecular_name (12)
Other_nameCELE_F16H9.1Accession_evidenceNDBBX284606
Public_namergs-2
DB_infoDatabaseAceViewgeneXN345
WormQTLgeneWBGene00004345
WormFluxgeneWBGene00004345
NDBlocus_tagCELE_F16H9.1
PanthergeneCAEEL|WormBase=WBGene00004345|UniProtKB=P49808
familyPTHR10845
NCBIgene181414
RefSeqproteinNM_001270270.5
NM_001392863.1
NM_077723.6
NM_001129662.4
SwissProtUniProtAccP49808
TrEMBLUniProtAccG5EFV0
G5ECA3
G5EFC5
UniProt_GCRPUniProtAccP49808
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrgs
Allele (258)
StrainWBStrain00026362
WBStrain00026360
RNASeq_FPKM (74)
GO_annotation00011399
00047258
Ortholog (47)
ParalogWBGene00004344Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00004346Caenorhabditis elegansFrom_analysisPanther
WBGene00004347Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004354Caenorhabditis elegansFrom_analysisPanther
WBGene00004353Caenorhabditis elegansFrom_analysisPanther
WBGene00004350Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00001145Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001179Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004349Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionrgs-2 encodes a regulator of G protein signaling; by homology, RGS-2 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-2 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-2 appears to function redundantly with rgs-1 to regulate egg-laying behavior when animals are refed following starvation; rgs-2 is expressed in pharyngeal and uterine muscles and in a subset of neurons, including neurons in the ventral cord and head- and tail-ganglia.Paper_evidenceWBPaper00004281
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Expressed in head neurons; pharyngeal muscle cell; tail neurons; uterine muscle; and ventral cord neurons. Is an ortholog of human RGS19 (regulator of G protein signaling 19).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF16H9.1a
F16H9.1b
F16H9.1c
F16H9.1d
Corresponding_transcriptF16H9.1a.1
F16H9.1b.1
F16H9.1c.1
F16H9.1d.1
Other_sequenceAF220265
MH05235
NBC03903_1
ACC11519_1
Oden_isotig17133
FC539539.1
Dviv_isotig22353
MCC03486_1
ACC16432_1
AM743496.1
CB038553.1
Oden_isotig17134
RS08557
JI257387.1
RSC01094_1
MC01937
HG11628
JI182595.1
EY460700.1
EY463440.1
HC01098
EY463951.1
HGC02312_1
EY473701.1
TDC02969_1
HCC10724_1
AS10509
MHC01780_1
NB09494
FC540810.1
EX542567.1
EY471953.1
TDC00834_1
NB09618
FC544746.1
ASC02359_1
Acan_contig10376
FC539576.1
EY471741.1
BMC09053_1
Associated_feature (22)
Experimental_infoRNAi_resultWBRNAi00112305Inferred_automaticallyRNAi_primary
WBRNAi00044841Inferred_automaticallyRNAi_primary
WBRNAi00013436Inferred_automaticallyRNAi_primary
WBRNAi00031054Inferred_automaticallyRNAi_primary
WBRNAi00112304Inferred_automaticallyRNAi_primary
WBRNAi00112307Inferred_automaticallyRNAi_primary
WBRNAi00112306Inferred_automaticallyRNAi_primary
WBRNAi00112303Inferred_automaticallyRNAi_primary
WBRNAi00112308Inferred_automaticallyRNAi_primary
WBRNAi00112309Inferred_automaticallyRNAi_primary
Expr_patternExpr1049
Expr11589
Expr1019382
Expr1032163
Expr1148805
Expr2015325
Expr2033559
Drives_constructWBCnstr00000298
WBCnstr00004866
WBCnstr00008978
WBCnstr00010049
WBCnstr00035551
Construct_productWBCnstr00004866
WBCnstr00010049
WBCnstr00035551
AntibodyWBAntibody00001586
Microarray_results (34)
Expression_cluster (158)
InteractionWBInteraction000001127
WBInteraction000029707
WBInteraction000115573
WBInteraction000121226
WBInteraction000134091
WBInteraction000147259
WBInteraction000166786
WBInteraction000169436
WBInteraction000169581
WBInteraction000169635
WBInteraction000173748
WBInteraction000189780
WBInteraction000207056
WBInteraction000233114
WBInteraction000233161
WBInteraction000247440
WBInteraction000289300
WBInteraction000301679
WBInteraction000326438
WBInteraction000342425
WBInteraction000361601
WBInteraction000399668
WBInteraction000418252
WBInteraction000440107
WBInteraction000505068
WBInteraction000521530
WBInteraction000541142
WBInteraction000541778
WBInteraction000551194
WBInteraction000557657
WBInteraction000557658
WBInteraction000569524
WBInteraction000569526
Map_info (4)
Reference (17)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene