WormBase Tree Display for Gene: WBGene00003167
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WBGene00003167 | SMap | S_parent | Sequence | F01D4 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | mec | ||||||
Reference_allele | WBVar00143928 | ||||||
Allele (57) | |||||||
Legacy_information | e1338 : touch insensitive lethargic microtubule cells small and lacking processes ALM and PLM cells displaced. ES2 ME2. NA8 (e1498 e1612 etc.). | ||||||
Class 2 revertant allele e1498u124 : ALM and PLM processes abnormally long. | |||||||
See also e1338 | |||||||
[C.elegansII] e1338 : touch insensitive, lethargic; microtubule cells small and lacking processes, ALM and PLM cells displaced. ES2 ME2. OA>10: e1498, e1612, u467amb, etc. Also revertant allele e1498u124 (ALM and PLM processes abnormally long). Cloned: encodes LIM class homeoprotein,expressed in touch receptors, FLP, PVD;extensive molecular analysis. [Way and Chalfie 1989; Xue et al. 1993; JW; TU] | |||||||
Strain | WBStrain00026815 | ||||||
WBStrain00027146 | |||||||
WBStrain00037306 | |||||||
WBStrain00037744 | |||||||
WBStrain00004302 | |||||||
WBStrain00006370 | |||||||
WBStrain00007579 | |||||||
WBStrain00052610 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (34) | |||||||
Ortholog (31) | |||||||
Paralog | WBGene00000438 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00002987 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00002988 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00002989 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
WBGene00003000 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00006654 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00006824 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00015216 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00017644 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00022518 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | mec-3 encodes a founding member of the LIM (Lin-11, Isl-1, Mec-3) homeodomain family of transcriptional regulators; during C. elegans development, MEC-3 activity is required for proper differentiation and maturation of the mechanosensory neurons; MEC-3 is expressed in the mechanosensory neurons, where initiation of expression is dependent upon the UNC-86 homeodomain protein and maintenance of expression is dependent upon MEC-3 itself and mec-17. | Paper_evidence | WBPaper00000502 | |||
WBPaper00001052 | |||||||
WBPaper00001237 | |||||||
WBPaper00001829 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 02 Sep 2005 00:00:00 | ||||||
Automated_description | Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including mechanosensory behavior; neuron projection organization; and positive regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex. Expressed in VA neuron; touch receptor neurons; ventral nerve cord; and vulva. Is an ortholog of human LHX1 (LIM homeobox 1) and LHX5 (LIM homeobox 5). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F01D4.6a | |||||
F01D4.6c | |||||||
F01D4.6d | |||||||
Corresponding_CDS_history | F01D4.6:wp49 | ||||||
F01D4.6b:wp243 | |||||||
Corresponding_transcript | F01D4.6a.1 | ||||||
F01D4.6c.1 | |||||||
F01D4.6d.1 | |||||||
Other_sequence (12) | |||||||
Associated_feature (31) | |||||||
Gene_product_binds (12) | |||||||
Transcription_factor | WBTranscriptionFactor000297 | ||||||
WBTranscriptionFactor000756 | |||||||
Experimental_info | RNAi_result | WBRNAi00115820 | Inferred_automatically | RNAi_primary | |||
WBRNAi00084972 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00012719 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00043722 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (12) | |||||||
Drives_construct (57) | |||||||
Construct_product | WBCnstr00004796 | ||||||
WBCnstr00006742 | |||||||
WBCnstr00009233 | |||||||
WBCnstr00010886 | |||||||
WBCnstr00015361 | |||||||
WBCnstr00016864 | |||||||
WBCnstr00019329 | |||||||
WBCnstr00036203 | |||||||
Antibody | WBAntibody00001500 | ||||||
WBAntibody00001560 | |||||||
Microarray_results (24) | |||||||
Expression_cluster (109) | |||||||
Interaction (225) | |||||||
WBProcess | WBbiopr:00000002 | ||||||
Map_info | Map | IV | Position | 4.59786 | Error | 0.000702 | |
Well_ordered | |||||||
Positive | Inside_rearr | sDf2 | |||||
Positive_clone | F01D4 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
TU#3 | |||||||
Mapping_data | 2_point | 112 | |||||
Multi_point (19) | |||||||
Pos_neg_data | 1650 | ||||||
1651 | |||||||
1652 | |||||||
1653 | |||||||
1654 | |||||||
1655 | |||||||
3869 | |||||||
Reference (256) | |||||||
Method | Gene |