WormBase Tree Display for Gene: WBGene00016892

WBGene00016892 SMap: S_parent: Sequence: C53A3
  Identity: Version: 2
    Name (5)
    DB_info: Database: AceView gene 5G242
        WormQTL gene WBGene00016892
        WormFlux gene WBGene00016892
        NDB locus_tag CELE_C53A3.2
        Panther gene CAEEL|WormBase=WBGene00016892|UniProtKB=O44538
          family PTHR19288
        NCBI gene 178964
        RefSeq protein NM_072110.6
        TrEMBL UniProtAcc O44538
        UniProt_GCRP UniProtAcc O44538
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
              Name_change: CGC_name: pgph-3
        2 23 Sep 2018 21:25:24 WBPerson1983 Name_change: CGC_name: pgph-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pgph
    Allele (12)
    RNASeq_FPKM (74)
    GO_annotation: 00032788
      00032789
      00032790
      00032791
      00122398
    Ortholog (79)
    Paralog: WBGene00007548 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00016664 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00019522 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00019604 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00018424 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable phosphatase activity. Predicted to be located in cytoplasm. Is an ortholog of human PDXP (pyridoxal phosphatase) and PGP (phosphoglycolate phosphatase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C53A3.2
    Corresponding_transcript: C53A3.2.1
    Other_sequence (61)
    Associated_feature: WBsf652649
      WBsf718314
      WBsf1019684
      WBsf233721
  Experimental_info: RNAi_result (11)
    Expr_pattern: Chronogram840
      Expr5575
      Expr1018417
      Expr1037249
      Expr1147017
      Expr2001873
      Expr2020099
    Drives_construct: WBCnstr00004425
      WBCnstr00027722
    Construct_product: WBCnstr00027722
    Microarray_results (12)
    Expression_cluster: WBPaper00029359_1280
      WBPaper00029359_1444
      WBPaper00029359_1504
      WBPaper00029359_1604
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00042034:NO_upregulated_N2
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044316:CH3HgCl_2.0uM_upregulated
      WBPaper00044426:rotenone_5day_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044786:emr-1(gk119)_upregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00046024:sleep_upregulated_oscillating
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048690:hermaphrodite-Z1-Z4_enriched
      WBPaper00048690:male-Z1-Z4_enriched
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00048988:neuron_expressed
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049368:daf-2(e1370)_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_8
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:HeatShock_downregulated_hsf-1(+)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050096:P.aeruginosa_downregulated
      WBPaper00050332:juglone_upregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_adult_25C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051265:F1_hrde-1(tm1200)_upregulated
      WBPaper00051265:F1_morc-1(tm6048)_upregulated
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00051388:Glucose-diet_upregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051404:alg-5(ram2)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053402:cco-1(RNAi)_downregulated
      WBPaper00053771:up_at_3h-NaCl
      WBPaper00053771:up_at_24h-NaCl
      WBPaper00053771:up_at_dpy-7(e88)
      WBPaper00053810:clk-1(qm30)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00053814:OP50_vs_PY79_upregulated_PY79
      WBPaper00054872:egl-9(sa307)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_downregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056034:pals-25(jy9)_downregulated
      WBPaper00056039:ptrn-1(tm5597)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:flcn-1(ok975)_upregulated
      WBPaper00056586:kri-1(ok1251)_downregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056826:SGP_biased
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057196:raga-1(ok386)_upregulated)
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00058711:skn-1(lax188)_downregulated
      WBPaper00058711:wdr-5(ok1417)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_PA14
      WBPaper00058948:PA14_upregulated
      WBPaper00059175:hlh-17p-XBP-1_downregulated
      WBPaper00059194:klf-1(RNAi)_regulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059440:LAG-1_interacting_WholeAnimal
      WBPaper00059529:nonu-1(srf0780)_upregulated
      WBPaper00059537:ngn-1(ok2200)_downregulated
      WBPaper00059566:P.luminescens_downregulated
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059735:glucose_upregulated_lpin-1(RNAi)
      WBPaper00059735:glucose_upregulated_N2
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059895:wounding_downregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_lin-40(yth27)
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061007:HB115_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061045:Y56A3A.22(cck200)_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061340:hyp7_C_lineage
      WBPaper00061340:Intestine
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061466:nath-10(icb102)_upregulated
      WBPaper00061478:pie-1(ne4433)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061527:tars-1-AFFX-r2-3026-5_at
      WBPaper00061651:ASJ_enriched
      WBPaper00061651:Coelomocyte_enriched
      WBPaper00061692:acivicin_downregulated
      WBPaper00061699:daf-18(ok480)_upregulated
      WBPaper00061753:csr-1(tor159)_downregulated_20C
      WBPaper00061800:miR-85(n4117)_upregulated_20C
      WBPaper00061853:osm-3(dh441)_downregulated
      WBPaper00061853:osm-3(dh441)_downregulated_tunicamycin
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:daf-16(RNAi)_upregulated
      WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00062587:lsl-1(ljm1)_upregulated
      WBPaper00062587:lsl-1(tm4769)_upregulated
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00064502:spe-44(fx110)_downregulated
      WBPaper00064532:pals-22(jy3)_downregulated
      WBPaper00064532:pals-25(jy111)_downregulated
      WBPaper00064602:egl-9(sa307)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064762:freezing-thaw_regulated
      WBPaper00064788:ketamine_downregulated
      WBPaper00064871:PA14_downregulated_AWA
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065005:sams-3(RNAi)_upregulated
      WBPaper00065005:sams-4(RNAi)_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065225:nhr-42(tm1375)_downregulated_S.aureus-infected
      WBPaper00065272:dhgd-1(tm6671)_downregulated
      WBPaper00065288:mdt-15(tm2182)_downregulated
      WBPaper00065734:unc-25(e156)_downregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065746:tmc-1(rg1003)_upregulated
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065749:Heat-Shock_upregulated_N2
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065835:mtH2S-AP39-L1-treatment_upregulated_Day11
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00065993:mml-1(RNAi)-neuron_downregulated
      WBPaper00065993:mxl-2(RNAi)-neuron_downregulated
      WBPaper00065995:M.humicola-extract_downregulated_N2
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066085:hda-3(ok1991)_upregulated
      WBPaper00066085:sin-3(syb2172)_upregulated
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066118:cyclobutrifluram_downregulated
      WBPaper00066204:CdCl2_upregulated_mRNA
      cgc4489_group_8
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026952:class_A
      WBPaper00027342:alpha-Synuclein(A53T)_upregulated
      WBPaper00027342:alpha-Synuclein(WT)_upregulated
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00034757:down_by_oxidative_stress
      WBPaper00035479:daf-16(RNAi)_upregulated
      WBPaper00035479:glucose_upregulated
      WBPaper00035560:ahr-1_downregulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-7_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035873:osm-11_regulated
      WBPaper00035873:osmotically_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_C
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00037113:CPF_16C_down-regulated
      WBPaper00037113:CPF_DZN_16C_down-regulated
      WBPaper00037611:RNP-8-associated
      WBPaper00037695:WC_5-day
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00038304:octr-1_regulated
      WBPaper00039866:ClassComp_daf-19_downregulated
      WBPaper00040185:nhr-23(RNAi)_downregulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040963:Q50_up
      WBPaper00040963:TA300_down
      WBPaper00040998:nhr-80_regulated
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042234:xpa-1_upregulated
      WBPaper00042236:flcn-1(ok975)_upregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045263:ProLongevity-mtROS_downregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00050767:Octopamine_induced
      WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc6390]:Cluster_C
      [cgc6390]:male_sex-enriched
    Interaction (15)
  Map_info: Map: V Position: -1.00941
    Positive: Positive_clone: C53A3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027108
    WBPaper00038491
    WBPaper00055090
    WBPaper00062352
    WBPaper00063033
    WBPaper00065341
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene