WormBase Tree Display for Gene: WBGene00016849

WBGene00016849 SMap: S_parent: Sequence: C50H11
  Identity: Version: 2
    Name: CGC_name: acs-21 Person_evidence: WBPerson237
            WBPerson2239
      Sequence_name: C50H11.1
      Molecular_name: C50H11.1
        C50H11.1.1
        CE08917
      Other_name: CELE_C50H11.1 Accession_evidence: NDB BX284605
      Public_name: acs-21
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 11 Sep 2008 09:57:25 WBPerson2970 Name_change: CGC_name: acs-21
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: acs
    Allele (140)
    RNASeq_FPKM (74)
    GO_annotation: 00028150
      00028151
    Ortholog (30)
    Paralog: WBGene00009221 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012356 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00018269 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00018579 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018488 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00006351 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00007969 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00013440 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable medium-chain fatty acid-CoA ligase activity. Predicted to be involved in fatty acid metabolic process. Human ortholog(s) of this gene implicated in combined malonic and methylmalonic acidemia. Is an ortholog of human ACSF3 (acyl-CoA synthetase family member 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111263 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:27288)
  Molecular_info: Corresponding_CDS: C50H11.1
    Corresponding_transcript: C50H11.1.1
    Other_sequence: Tcol_isotig16126
      FC817579.1
      Oden_isotig23555
      SR02202
      FC811977.1
      SRC02513_1
    Associated_feature: WBsf231547
  Experimental_info: RNAi_result: WBRNAi00012247 Inferred_automatically: RNAi_primary
      WBRNAi00042960 Inferred_automatically: RNAi_primary
      WBRNAi00030057 Inferred_automatically: RNAi_primary
    Expr_pattern (5)
    Drives_construct: WBCnstr00027755
    Construct_product: WBCnstr00027755
    Microarray_results (23)
    Expression_cluster: WBPaper00031040:Cluster_4
      WBPaper00032425:down_in_rde-4
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00040560:hpl-2_L3_downregulated
      WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044578:reduced-humidity_upregulated_microarray
      WBPaper00044638:daf-2(e1370)rsks-1(ok1255)_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Oogenic
      WBPaper00045774:clk-1_upregulated
      WBPaper00048690:hermaphrodite-Z1-Z4_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049368:daf-2(e1370)_upregulated
      WBPaper00049736:15deg-then-25deg(12hr)_upregulated_N2
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:intestine_expressed
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053810:sod-2(ok1030)_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060278:atp-2(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060909:atfs-1(et18)_upregulated
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061527:nhr-107_19485-nhr-109_3743
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:daf-16(RNAi)_downregulated
      WBPaper00062456:doxycycline_upregulated_CB4856_protein
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_7
      WBPaper00032948:StarveUp2
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_B
      WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_prime
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045263:ProLongevity-mtROS_upregulated
      WBPaper00049538:atfs-1(et18)_upregulated
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction (33)
  Map_info: Map: V Position: -12.757 Error: 0.003186
    Positive: Positive_clone: C50H11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00042257
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene