| WBGene00015646 | SMap | S_parent | Sequence | C09E8 |
|---|
| Identity | Version | 2 |
| | Name | CGC_name | mlt-10 | Person_evidence | WBPerson545 |
| | | | | | WBPerson3379 |
| | | Sequence_name | C09E8.3 |
| | | Molecular_name | C09E8.3 |
| | | | C09E8.3.1 |
| | | | CE19349 |
| | | Other_name | C09E8.a | Curator_confirmed | WBPerson1983 |
| | | | | Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs |
| | | | CELE_C09E8.3 | Accession_evidence | NDB | BX284602 |
| | | Public_name | mlt-10 |
| | DB_info | Database | AceView | gene | 2A841 |
| | | | WormQTL | gene | WBGene00015646 |
| | | | WormFlux | gene | WBGene00015646 |
| | | | NDB | locus_tag | CELE_C09E8.3 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00015646|UniProtKB=O76555 |
| | | | | family | PTHR21523 |
| | | | NCBI | gene | 173445 |
| | | | RefSeq | protein | NM_061354.5 |
| | | | TREEFAM | TREEFAM_ID | TF315329 |
| | | | TrEMBL | UniProtAcc | O76555 |
| | | | UniProt_GCRP | UniProtAcc | O76555 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 28 May 2004 13:30:56 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 |
| | | | 2 | 28 Jul 2005 14:21:20 | WBPerson2970 | Name_change | CGC_name | mlt-10 |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | mlt |
| | Allele (107) |
| | Strain | WBStrain00007913 |
| | | WBStrain00007925 |
| | | WBStrain00007926 |
| | | WBStrain00007927 |
| | | WBStrain00032646 |
| | RNASeq_FPKM (74) |
| | GO_annotation | 00038482 |
| | | 00038483 |
| | | 00038484 |
| | | 00038485 |
| | Ortholog (39) |
| | Paralog (13) |
| | Structured_description | Concise_description | mlt-10 encodes a nematode-specific protein that contains a domain of unknown function, DUF644, and tandem proline- and hydroxy amino acid-rich repeats; mlt-10 is required for proper execution of the molting cycle, as well as a number of other processes including normal body shape, locomotion, and reproduction; MLT-10 is expressed transiently with each molting cycle in the hypodermis, except for the lateral seam cells, and in the pharyngeal myoepithelium; MLT-10 is secreted into the surrounding matrix and fluids during molting and also found in strands near the animal surface; mlt-10 expression in the hypodermis depends upon the nuclear hormone receptors NHR-23 and NHR-25; MLT-10 contains thirteen paralogs in the C. elegans genome that, along with MLT-10, are all members of a large family of conserved nematode proteins. | Paper_evidence | WBPaper00036066 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 26 Mar 2010 00:00:00 |
| | | Automated_description | Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and epidermis development. Located in extracellular space. Expressed in hypodermal cell and pharyngeal epithelial cell. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | C09E8.3 |
| | Corresponding_transcript | C09E8.3.1 |
| | Other_sequence | EX547584.1 |
| | | ACC41112_1 |
| | | SSC03996_1 |
| | | CBC13394_1 |
| | | JI468824.1 |
| | | BXC01140_1 |
| | Associated_feature | WBsf643913 |
| | | WBsf717623 |
| | | WBsf717624 |
| | | WBsf986435 |
| | | WBsf220766 |
| | | WBsf220767 |
| Experimental_info | RNAi_result | WBRNAi00010520 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00040201 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00028724 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00098168 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Chronogram1648 |
| | | Expr3696 |
| | | Expr9014 |
| | | Expr9015 |
| | | Expr1022256 |
| | | Expr1036700 |
| | | Expr1144271 |
| | | Expr2013604 |
| | | Expr2031837 |
| | Drives_construct | WBCnstr00000978 |
| | | WBCnstr00006118 |
| | | WBCnstr00006119 |
| | | WBCnstr00006887 |
| | | WBCnstr00011607 |
| | | WBCnstr00013673 |
| | | WBCnstr00028689 |
| | Construct_product (5) |
| | Microarray_results (22) |
| | Expression_cluster | WBPaper00024375:Up_N2_vs_vhl-1 |
| | | WBPaper00033065:cyc-1(RNAi)_downregulated |
| | | WBPaper00037950:A-class-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:AVE-neuron_L1-larva_expressed |
| | | WBPaper00037950:bodywall-muscle_L1-larva_expressed |
| | | WBPaper00037950:coelomocytes_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L1-larva_expressed |
| | | WBPaper00037950:germline-precursors_blastula-embryo_expressed |
| | | WBPaper00037950:germline-precursors_embryo_enriched |
| | | WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched |
| | | WBPaper00037950:hypodermis_embryo_enriched |
| | | WBPaper00037950:hypodermis_embryo_SelectivelyEnriched |
| | | WBPaper00037950:hypodermis_L1-larva_expressed |
| | | WBPaper00037950:hypodermis_L3-L4-larva_expressed |
| | | WBPaper00037950:pharyngeal-muscle_L1-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq |
| | | WBPaper00038438:Harposporium_24hr_downregulated_RNAseq |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray |
| | | WBPaper00040134:nhr-49(RNAi)_regulated_protein |
| | | WBPaper00042034:NO_upregulated_hsf-1(sy441) |
| | | WBPaper00042194:nhr-114(RNAi)_downregulated |
| | | WBPaper00043945:MeHg_upregulated |
| | | WBPaper00044260:1-methylnicotinamide_upregulated |
| | | WBPaper00044578:reduced-humidity_downregulated_microarray |
| | | WBPaper00044736:oscillating_dev_expression |
| | | WBPaper00044760:somatic_specific |
| | | WBPaper00044857:BAR-1_upregulated |
| | | WBPaper00045257:bar-1(ga80)_downregulated |
| | | WBPaper00045417:128Q-huntingtin_upreglated |
| | | WBPaper00045521:Oogenic |
| | | WBPaper00045729:gld-2(RNAi)_downregulated |
| | | WBPaper00045934:wrn-1(gk99)_upregulated |
| | | WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h |
| | | WBPaper00046497:B.thuringiensis_downregulated_protein |
| | | WBPaper00046805:csr-1(RNAi)_downregulated_Set1 |
| | | WBPaper00046805:csr-1(RNAi)_downregulated_Set2 |
| | | WBPaper00048971:daf-16(mgDf50)_upregulated_L1 |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049018:swsn-2.2(RNAi)_downregulated |
| | | WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated |
| | | WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031) |
| | | WBPaper00050370:dpy-21(e428)_L3_downregulated |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C |
| | | WBPaper00050726:OsmoticStress_regulated_Food |
| | | WBPaper00050726:OsmoticStress_regulated_NoFood |
| | | WBPaper00050801:DAF-12_dauer_regulome |
| | | WBPaper00050801:DAF-16_dauer_regulome |
| | | WBPaper00050801:DPY-21_dauer_regulome |
| | | WBPaper00050801:SET-4_dauer_regulome |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050990:hypodermis_enriched |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00051021:4-bromodiphenyl-ether_downregulated |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051404:alg-1(gk214)_downregulated |
| | | WBPaper00051404:alg-2(ok304)_downregulated |
| | | WBPaper00052884:emb-4(hc60)_upregulated |
| | | WBPaper00053020:sid-3(ok973)_upregulated |
| | | WBPaper00053020:sta-1(ok587)_upregulated |
| | | WBPaper00053184:sma-2(rax5)_upregulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053295:lin-22(ot269)_upregulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053321:PGCs_depleted_NuGen |
| | | WBPaper00053388:dauer_regulated_Cluster6 |
| | | WBPaper00053402:cco-1(RNAi)_downregulated |
| | | WBPaper00053599:female_vs_male_upregulated |
| | | WBPaper00053599:oocyte_vs_mitosis_downregulated |
| | | WBPaper00053810:nuo-6(qm200)_downregulated |
| | | WBPaper00054410:set-9(rw5)_downregulated |
| | | WBPaper00054410:set-26(tm2467)_downregulated |
| | | WBPaper00054493:hpl-2(tm1489)_upregulated |
| | | WBPaper00054872:egl-9(sa307)_upregulated |
| | | WBPaper00055013:hmg-3(bar24)_downregulated |
| | | WBPaper00055013:hmg-4(RNAi)_downregulated |
| | | WBPaper00055013:spt-16(RNAi)_downregulated |
| | | WBPaper00055049:S.gordonii_upregulated |
| | | WBPaper00055354:eat-2(ad1116)_upregulated |
| | | WBPaper00055354:Rapamycin-Metformin_upregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated |
| | | WBPaper00055941:nuo-6(qm200)_downregulated |
| | | WBPaper00056039:ptrn-1(tm5597)_downregulated |
| | | WBPaper00056139:soil-microbiota_upregulated |
| | | WBPaper00056169:rrf-3(pk1426)_downregulated_L4 |
| | | WBPaper00056169:rrf-3(pk1426)_upregulated_L2 |
| | | WBPaper00056290:hsp-6(mg585)_upregulated |
| | | WBPaper00056290:mdt-15(mg584)_upregulated |
| | | WBPaper00056293:rpl-5(0)-rpl-33(0)_downregulated |
| | | WBPaper00056330:glycine_downregulated |
| | | WBPaper00056443:DietaryRestriction_upregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated |
| | | WBPaper00056471:S.aureus-4h_downregulated_N2 |
| | | WBPaper00057041:spc-1(cas971)_upregulated |
| | | WBPaper00057041:unc-70(cas983)_upregulated |
| | | WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium |
| | | WBPaper00057068:numr-1(RNAi)_downregulated |
| | | WBPaper00057154:HeatShock_upregulated_mRNA |
| | | WBPaper00057347:nhr-14(tm1473)_downreglated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058711:paraquat_upregulated |
| | | WBPaper00058927:high-redox-state_upregulated |
| | | WBPaper00058948:npr-8(ok1439)_downregulated_PA14 |
| | | WBPaper00058948:PA14_downregulated |
| | | WBPaper00058958:100mGy-irradiation-72h_upregulated |
| | | WBPaper00058969:RIS_depleted |
| | | WBPaper00059117:B.subtilis_upregulated |
| | | WBPaper00059231:alh-6(lax105)_L4_upregulated |
| | | WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA |
| | | WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated |
| | | WBPaper00059421:daf-3(mgDf90)_downregulated |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00059728:5ug_cholesterol_upregulated |
| | | WBPaper00059728:20ug_cholesterol_upregulated |
| | | WBPaper00059739:hira-1(gk835598)_downregulated_L4 |
| | | WBPaper00059739:hira-1(gk835598)_upregulated_adult |
| | | WBPaper00060014:set-2(tm1630)_downregulated |
| | | WBPaper00060084:cco-1(RNAi)_downregulated_N2 |
| | | WBPaper00060273:isp-1(qm150)_upregulated |
| | | WBPaper00060273:vrk-1(RNAi)_downregulated |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_N2 |
| | | WBPaper00060445:nfki-1(cer1)_downregulated_L4 |
| | | WBPaper00060459:bcat-1(RNAi)_downregulated |
| | | WBPaper00060661:sensory-neuron_depleted |
| | | WBPaper00060683:hlh-11(ko1)_upregulated |
| | | WBPaper00060764:swsn-1(os22ts)_downregulated |
| | | WBPaper00060811:L1_vs_adult_downregulated_neural |
| | | WBPaper00060871:M.humicola-infection_12h_regulated |
| | | WBPaper00060909:atfs-1(et18)_downregulated |
| | | WBPaper00061007:HB101_upregulated |
| | | WBPaper00061007:HB115_upregulated |
| | | WBPaper00061007:M.braciatum_upregulated |
| | | WBPaper00061007:S.aquatilis_upregulated |
| | | WBPaper00061007:X.citri_upregulated |
| | | WBPaper00061106:endu-2(tm4977)_upregulated |
| | | WBPaper00061203:let-418(n3536)_upregulated |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061274:hypergravity_10xg_upregulated |
| | | WBPaper00061274:hypergravity_15xg_upregulated |
| | | WBPaper00061340:Hypodermis |
| | | WBPaper00061424:Diet_MYb120_upregulated |
| | | WBPaper00061439:unc-30(ok613)_upregulated |
| | | WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection |
| | | WBPaper00061527:dos-2-grd-2 |
| | | WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated |
| | | WBPaper00061699:daf-18(ok480)_upregulated |
| | | WBPaper00061853:osm-3(dh441)_downregulated_tunicamycin |
| | | WBPaper00062056:lin-15B(we23)_downregulated |
| | | WBPaper00062156:jmjd-1.2(zr1010)_upregulated |
| | | WBPaper00062156:jmjd-5(zr1234)_upregulated |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062193:skn-1(RNAi)_downregulated |
| | | WBPaper00062446:nhr-8(hd117)_upregulated |
| | | WBPaper00062534:fat-P-80_downregulated |
| | | WBPaper00062534:fat-P-80_downregulated_ech-6(RNAi) |
| | | WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium |
| | | WBPaper00062669:extracellular-vesicle_protein |
| | | WBPaper00062715:blmp-1(s71)_upregulated |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064107:lin-35(n745)_downregulated |
| | | WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated |
| | | WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs |
| | | WBPaper00064532:pals-25(icb98)_downregulated |
| | | WBPaper00064539:nhr-114(gk849)_downregulated |
| | | WBPaper00064716:paraquat_upregulated |
| | | WBPaper00064727:daf-2(e1370)_upregulated |
| | | WBPaper00064728:cpl-1(W32AY35A)_upregulated |
| | | WBPaper00064769:him-17(me24)_downregulated |
| | | WBPaper00064933:bcf-1(ylf1)_upregulated_transcript |
| | | WBPaper00065096:25C_vs_20C_downregulated |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065120:body-muscle-transcriptome |
| | | WBPaper00065373:Cisplatin_downregulated_WT |
| | | WBPaper00065373:sek-1(km4)_downregulated_Ref |
| | | WBPaper00065581:hpk-1(pk1393)_upregulated |
| | | WBPaper00065746:eat-2(ad1113)_downregulated |
| | | WBPaper00065835:Day11_vs_Day1_upregulated |
| | | WBPaper00065835:mtH2S-AP39-D0-treatment_downregulated_Day11 |
| | | WBPaper00065841:33_1 |
| | | WBPaper00065841:40_0 |
| | | WBPaper00065841:82_0 |
| | | WBPaper00065841:129_0 |
| | | WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein |
| | | WBPaper00065945:epidermis-rpoa-2(-)_downregulated_transcript |
| | | WBPaper00065945:global-rpoa-2(-)_downregulated_transcript |
| | | WBPaper00065975:P-body_vs_oocyte_enriched |
| | | WBPaper00065975:P-body_vs_WholeAnimal_enriched |
| | | WBPaper00065984:pals-17(syb3980)_downregulated |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | WBPaper00066004:tdp-1(csb38)_upregulated |
| | | WBPaper00066110:tetraploid_vs_diploid_upregulated |
| | | WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14 |
| | | cgc4386_cluster_4_6 |
| | | cgc4489_group_8 |
| | | WBPaper00005475:Aging-regulated |
| | | WBPaper00024393:strongly_regulated_dauer_genes |
| | | WBPaper00026929:Resveratrol_regulated_daf-16 |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00026952:class_E |
| | | WBPaper00026980:intestine_enriched |
| | | WBPaper00031252:AIN-1_IP_enriched |
| | | WBPaper00031252:AIN-2_IP_enriched |
| | | WBPaper00032165:differentially_expressed_with_age_medoid_2 |
| | | WBPaper00032948:FedUp |
| | | WBPaper00032948:MoltOssilate |
| | | WBPaper00033101:spr-5_regulated |
| | | WBPaper00034661:AgNPs_downregulated |
| | | WBPaper00035084:embryo_enriched_AIN-2_IP |
| | | WBPaper00035873:dpy-9_regulated |
| | | WBPaper00035873:dpy-10_regulated |
| | | WBPaper00035873:osm-8_regulated |
| | | WBPaper00036130:mir-243_up_regulated |
| | | WBPaper00036286:Pattern_G |
| | | WBPaper00038172:crh-1null_down_regulated |
| | | WBPaper00038172:tax-6null_down_regulated |
| | | WBPaper00038304:octr-1_regulated |
| | | WBPaper00038427:lin-54_embryo_changed |
| | | WBPaper00039866:ClassComp_daf-19_downregulated |
| | | WBPaper00040116:pRJ-FR.5_down_regulated |
| | | WBPaper00040185:nhr-23(RNAi)_downregulated |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2 |
| | | WBPaper00040821:Au-NP_regulated |
| | | WBPaper00040876:mir-35_downregulated |
| | | WBPaper00040963:Q50_up |
| | | WBPaper00041207:CE_dauer_down |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00041939:control_vs_EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00042128:gei-8(ok1671)_downregulated |
| | | WBPaper00042274:tbx-2(bx59)_downregulated |
| | | WBPaper00042331:a-SWCNTs_downregulated |
| | | WBPaper00042548:miRISC_enriched |
| | | WBPaper00044091:Bpseudomallei_repressed_12h |
| | | WBPaper00045673:colistin_upregulated |
| | | WBPaper00046083:oga-1(ok1207)_OP50_downregulated |
| | | WBPaper00046083:ogt-1(ok1474)_OP50_downregulated |
| | | WBPaper00046083:pmk-1(km25)_OP50_downregulated |
| | | WBPaper00046548:dafachronic-acid_upregulated |
| | | WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated |
| | | WBPaper00047070:N2_starvation_downregulated |
| | | WBPaper00047070:N2_UV_downregulated |
| | | WBPaper00047070:xpa-1_UV_downregulated |
| | | WBPaper00048989:N2_rapamycin_upregulated |
| | | WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo |
| | | WBPaper00056330:mrps-5(RNAi)_upregulated |
| | | [cgc6390]:Cluster_B |
| | Interaction (36) |
| Map_info | Map | II | Position | -15.5955 | Error | 0.000175 |
| | Positive | Positive_clone | C09E8 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference (13) |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
