WormBase Tree Display for Gene: WBGene00008476

WBGene00008476 SMap: S_parent: Sequence: E03H4
  Identity: Version: 1
    Name: Sequence_name: E03H4.8
      Molecular_name: E03H4.8
        E03H4.8.1
        CE09135
        E03H4.8.2
      Other_name: CELE_E03H4.8 Accession_evidence: NDB BX284601
      Public_name: E03H4.8
    DB_info: Database: AceView gene 1N14
        WormQTL gene WBGene00008476
        WormFlux gene WBGene00008476
        NDB locus_tag CELE_E03H4.8
        NCBI gene 184023
        RefSeq protein NM_060750.6
        TREEFAM TREEFAM_ID TF300688
        TrEMBL UniProtAcc O17742
        UniProt_GCRP UniProtAcc O17742
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (52)
    Strain: WBStrain00033060
    RNASeq_FPKM (74)
    GO_annotation: 00116370
      00116371
      00116372
      00116373
    Ortholog (36)
    Paralog: WBGene00009542 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00022119 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00270321 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: E03H4.8 encodes one of two C. elegans proteins with similarity to the beta' coat protein of the COPI vesicular coat; by homology, E03H4.8 is required for retrograde trafficking from the cis-Golgi to the endoplasmic reticulum and trafficking within the Golgi stack; in C. elegans, RNAi experiments indicate that E03H4.8 is required for proper germ cell development and reproduction; about 10% to 20% of E03H4.8 transcripts are RNA edited to change A to G resulting in a change to residue 331 from an S to a G. Paper_evidence: WBPaper00045975
            WBPaper00041129
            WBPaper00038381
          Curator_confirmed: WBPerson1843
            WBPerson4025
          Date_last_updated: 28 Dec 2014 00:00:00
      Automated_description: Predicted to enable structural molecule activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be part of membrane coat. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: E03H4.8
    Corresponding_transcript: E03H4.8.1
      E03H4.8.2
    Other_sequence: CJC14185_1
    Associated_feature: WBsf649662
      WBsf716957
      WBsf220428
  Experimental_info: RNAi_result (12)
    Expr_pattern: Expr1027574
      Expr1033687
      Expr1147644
      Expr2002153
      Expr2020373
    Drives_construct: WBCnstr00032941
    Construct_product: WBCnstr00032941
    Microarray_results (15)
    Expression_cluster: WBPaper00037946:LIN-39_interacting
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00040560:hpl-2_embryo_upregulated
      WBPaper00040560:hpl-2_L3_downregulated
      WBPaper00041954:ethanol_upregulated
      WBPaper00044316:CH3HgCl_2.0uM_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044786:lem-2(tm1582)_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045918:96h_infection_recovery_upregulated
      WBPaper00045974:NSM_enriched_DSN-treated_RNAseq
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00046509:htz-1(ok3099)_upregulated
      WBPaper00047132:skn-1(RNAi)_downregulated_glp-1(ts)-dependent
      WBPaper00048923:Aging_regulated
      WBPaper00048988:daf-16(mu86)_upregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049217:DAF-16_downregulated
      WBPaper00049489:AMsh-glia_enriched
      WBPaper00049498:npr-1(ur89)_regulated_5
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050096:P.aeruginosa_upregulated
      WBPaper00050182:lmn-1(L535P)_upregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_adult_25C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050496:unc-39(hp701)_regulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053318:mir-71(n4115)_upregulated_mRNA
      WBPaper00053402:his-3(RNAi)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053771:up_at_3h-NaCl
      WBPaper00053771:up_at_24h-NaCl
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055827:pfd-6(gk493446)_upregulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056039:hda-6(ok3203)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_L4
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00056868:P.aeruginosa_upregulated_smallRNA
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_downregulated
      WBPaper00057154:HeatShock_downregulated_mRNA
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059175:hlh-17p-XBP-1_upregulated
      WBPaper00059231:alh-6(lax105)_L4_downregulated
      WBPaper00059253:sucrose_downregulated
      WBPaper00059253:sucrose_stearic-acid_downregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060526:plp-1(ok2155)_downregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060703:nas-38(ok3407)_upregulated
      WBPaper00060909:atfs-1(et18)_upregulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061340:RMED
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061390:daf-22(ok693)_ascarosides_upregulated
      WBPaper00061527:fbxa-35-Y39A3A.3
      WBPaper00061853:tunicamycin_downregulated_N2
      WBPaper00062056:lin-35(n745)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062184:PA14_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062354:H.zoospora_12h_regulated
      WBPaper00062456:doxycycline_upregulated_CB4856_transcript
      WBPaper00062456:doxycycline_upregulated_N2_transcript
      WBPaper00062497:xpf-1(tm2842)_upregulated
      WBPaper00062520:qui-1(db104)_downregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064201:SNA-3_interacting
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064762:freezing-thaw_regulated
      WBPaper00064871:PA14_upregulated_AWA
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065749:Heat-Shock-With-Recovery_upregulated_N2
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_downregulated_Day11
      WBPaper00065841:13_0
      WBPaper00065841:13_1
      WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00028789:PA14_vs_gacA_upregulated_8hr
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035891:PA_induced_zip-2_dependent
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00036286:Pattern_F
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00044091:Bpseudomallei_induced_2h
      WBPaper00044091:Bpseudomallei_induced_4h
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00044091:Bpseudomallei_induced_12h
      WBPaper00045673:colistin_upregulated
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00047070:DAF-16-dependent_UV_response
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      WBPaper00050520:lagr-1(gk327);hyl-1(ok976)_upregulated
      WBPaper00051448:P.aeruginosa_Liquid-Killing_upregulated
    Interaction: WBInteraction000519797
      WBInteraction000580597
  Map_info: Positive: Positive_clone: E03H4 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: I 13.197
  Reference (3)
  Method: Gene