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WormBase Tree Display for Gene: WBGene00007848

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Name Class

WBGene00007848SMapS_parentSequenceC31E10
IdentityVersion2
NameCGC_namecytb-5.1Person_evidenceWBPerson681
Sequence_nameC31E10.7
Molecular_nameC31E10.7
C31E10.7.1
CE37487
Other_namecytochrome b5Paper_evidenceWBPaper00040883
CELE_C31E10.7Accession_evidenceNDBBX284606
Public_namecytb-5.1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:48WBPerson1971EventImportedInitial conversion from CDS class of WS125
230 Sep 2011 16:40:15WBPerson2970Name_changeCGC_namecytb-5.1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcytb
Allele (24)
RNASeq_FPKM (74)
GO_annotation00085658
00085659
00085660
00085661
00085662
00085663
00085664
00085665
Ortholog (48)
ParalogWBGene00010235Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00014300Caenorhabditis elegansFrom_analysisPanther
WBGene00020931Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptioncytb-5.1 encodes a protein orthologous to cytochrome b5; a CYTB-5.1 reporter fusion protein, when expressed in the distal tip cell, exhibits perinuclear localization, consistent with localization to the endoplasmic reticulum.Paper_evidenceWBPaper00040883
Curator_confirmedWBPerson1843
WBPerson1823
WBPerson567
Date_last_updated16 Mar 2012 00:00:00
Automated_descriptionPredicted to enable heme binding activity. Located in perinuclear region of cytoplasm. Used to study hematopoietic system disease. Human ortholog(s) of this gene implicated in methemoglobinemia; methemoglobinemia and ambiguous genitalia; and stomatitis. Is an ortholog of human CYB5A (cytochrome b5 type A) and CYB5B (cytochrome b5 type B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:74Homo sapiensPaper_evidenceWBPaper00053474
Curator_confirmedWBPerson324
Date_last_updated09 May 2023 00:00:00
Potential_modelDOID:0112316Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2570)
DOID:10783Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2570)
DOID:9637Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2570)
Models_disease_in_annotationWBDOannot00000049
Molecular_infoCorresponding_CDSC31E10.7
Corresponding_CDS_historyC31E10.7:wp132
Corresponding_transcriptC31E10.7.1
Other_sequence (80)
Associated_featureWBsf648705
WBsf655229
WBsf663528
WBsf1007797
WBsf1024340
WBsf236630
WBsf236631
WBsf236632
Experimental_infoRNAi_resultWBRNAi00033345Inferred_automaticallyRNAi_primary
WBRNAi00024689Inferred_automaticallyRNAi_primary
WBRNAi00071638Inferred_automaticallyRNAi_primary
WBRNAi00111894Inferred_automaticallyRNAi_primary
WBRNAi00008470Inferred_automaticallyRNAi_primary
WBRNAi00105933Inferred_automaticallyRNAi_primary
WBRNAi00071637Inferred_automaticallyRNAi_primary
WBRNAi00041615Inferred_automaticallyRNAi_primary
WBRNAi00088736Inferred_automaticallyRNAi_primary
WBRNAi00088629Inferred_automaticallyRNAi_primary
Expr_pattern (6)
Drives_constructWBCnstr00033436
Construct_productWBCnstr00000237
WBCnstr00033436
WBCnstr00040361
Microarray_results (20)
Expression_clusterWBPaper00005700:transmembrane_protein
WBPaper00028451:Low_abundance_spermatogenesis_enriched
WBPaper00031040:Cluster_5
WBPaper00031040:TGF-beta_adult_upregulated
WBPaper00032528:L3_enriched
WBPaper00032976:non_compensated_genes
WBPaper00033444:BacteriaDiet_regulated
WBPaper00035269:cde-1_regulated
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
WBPaper00040221:DAF-12_target_ALF4
WBPaper00040965:lipid-droplet_associated_protein
WBPaper00044128:daf-2(e1370)_upregulated
WBPaper00044260:1-methylnicotinamide_upregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:flat_dev_expression
WBPaper00045316:prg-1_downregulated_L2
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_upregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
WBPaper00046509:htz-1(ok3099)_downregulated
WBPaper00046509:lin-35(n745)_downregulated
WBPaper00048923:Aging_regulated
WBPaper00048926:miaserin_upregulated_adult-day3
WBPaper00048926:miaserin_upregulated_adult-day5
WBPaper00048926:miaserin_upregulated_adult-day10
WBPaper00048971:daf-16(mgDf50)_downregulated_L1
WBPaper00048988:neuron_expressed
WBPaper00049018:SWSN-2.2_interacting
WBPaper00049134:hpk-1(pk1393)_downregulated
WBPaper00049217:TCER-1_upregulated
WBPaper00049334:CE_intestine_enriched
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00050344:ASER-neuron_enriched
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051021:4-bromodiphenyl-ether_upregulated
WBPaper00051039:intestine_enriched
WBPaper00051245:cytoplasm_specific
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051404:alg-2(ok304)_downregulated
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(ot269)_downregulated
WBPaper00053302:stavudine_72h_regulated
WBPaper00053321:mes-2(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:mes-4(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053388:dauer_regulated_Cluster3
WBPaper00053599:female_vs_male_upregulated
WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
WBPaper00053810:isp-1(qm150)_downregulated
WBPaper00053814:OP50_vs_PY79_downregulated_PY79
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00055482:Tunicamycin_downregulated
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00055971:nhl-2(ok818)_20C_downregulated
WBPaper00056073:NHR-86_interacting_promoter
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_downregulated_N2
WBPaper00056290:mdt-15(mg584)_upregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056501:P.aeruginosa_upregulated_mitochondria-protein
WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059471:EGL-43_interacting
WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
WBPaper00059604:fluvastatin_downregulated_N2
WBPaper00060084:cco-1(RNAi)_downregulated_N2
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060661:sensory-neuron_enriched
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00060703:nas-38(ok3407)_downregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061274:microgravity_downregulated
WBPaper00061340:Parent_of_tail_spike_and_hyp10
WBPaper00061340:Y
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061527:vem-1-ugt-58
WBPaper00061530:nhr-49(e2144)_downregulated
WBPaper00061590:CGP37157_upregulated
WBPaper00061651:AMso_enriched
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062193:skn-1(RNAi)_upregulated
WBPaper00062345:bortezomib_4h_downregulated_N2
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00062456:doxycycline_upregulated_CB4856_protein
WBPaper00062590:Aging_upregulated_neuron
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064315:mes-3(bn199)_upregulated_EGCs
WBPaper00064315:mes-3(bn199)_upregulated_PGCs
WBPaper00064315:mes-4(bn73)_upregulated_EGCs
WBPaper00064315:mes-4(bn73)_upregulated_PGCs
WBPaper00064539:nhr-114(gk849)_upregulated
WBPaper00064716:paraquat_downregulated
WBPaper00064727:daf-2(e1370)_upregulated
WBPaper00064871:hypoxia_downregulated_F2
WBPaper00064992:Eugenol_downregulated
WBPaper00064992:heat-shock_upregulated
WBPaper00065086:JU1400_N.ausubeli_regulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065258:anchor-cell_enriched
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065849:ursolic-acid_regulated
WBPaper00065975:P-body_vs_oocyte_depleted
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
cgc4386_cluster_3_4
cgc4489_group_7
WBPaper00006465:II_ethanol_late_induction
WBPaper00025032:cluster_2
WBPaper00025141:N2_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00030985:Photorhabdus_luminescens_upregulated
WBPaper00031003:0hr_muscle_depleted
WBPaper00031003:24hr_muscle_depleted
WBPaper00031003:total_muscle_depleted
WBPaper00031850:mdt-15(RNAi)_downregulated
WBPaper00035479:daf-16(RNAi)_downregulated
WBPaper00036286:Pattern_C
WBPaper00037113:CPF_16C_up-regulated
WBPaper00038231:Cry5B_1.5-fold_downregulated
WBPaper00038231:Cry5B_2-fold_downregulated
WBPaper00038427:lin-54_germline_changed
WBPaper00039851:HK_C_albicans_vs_HK_OP50
WBPaper00039851:Live_C_albicans_vs_HK_OP50
WBPaper00040210:Chlorpyrifos_24C_regulated
WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
WBPaper00040426:CYD-1_CDK-4_downregulated
WBPaper00040823:alg-1(gk214)_upregulated
WBPaper00041002:HF_3d_0.2mM_Up
WBPaper00041002:HF_3d_2.0mM_Up
WBPaper00041002:HQ_3d_2.0mM_Up
WBPaper00041211:RPW-24_Up
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041960:N2_fasting_upregulated_9hto12h
WBPaper00041960:N2_fasting_upregulated_anytime
WBPaper00045673:colistin_upregulated
WBPaper00048567:dnj-14_downregulated
WBPaper00053236:daf-16(mgDF50)_regulated_Starved
WBPaper00053236:Starvation_regulated_GR1307
[cgc5767]:cluster_2
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(41_min)
[cgc5767]:expression_class_E_pi(53_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_ME
Interaction (55)
Map_infoMapXPosition15.9609
PositivePositive_cloneC31E10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00034497
WBPaper00034498
WBPaper00038491
WBPaper00040883
WBPaper00053474
WBPaper00055090
WBPaper00060223
WBPaper00061328
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene