WormBase Tree Display for Expression_cluster: WBPaper00048567:dnj-14_downregulated
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| WBPaper00048567:dnj-14_downregulated | Description | Genes that significantly decreased expression in dnj-14(ok237) and dnj-14(tm3223) when comparing to either N2 or CZ1200 juIs76 [unc-25p::GFP; lin-15(+)] | |
|---|---|---|---|
| Species | Caenorhabditis elegans | ||
| Algorithm | The significance test of the estimated logFC (log2 Fold Change) for each contrast was performed by the empirical Bayes function packed in limma and p-values were adjusted using the Benjamini and Hochberg FDR control approach to deal with the effect of multiple tests. Both 5% and 1% false discovery rate (FDR) datasets were analysed in order to ensure the highest confidence in the observed enriched genes and pathways whist ensuring there was no loss of representation of DEGs at higher stringency levels. At 5% FDR, 3569 DEGs were revealed compared to N2 (Bristol) and 506 DEGs compared to CZ1200. Further analysis of these data identified 50 Up-regulated and 240 down-regulated DEGs which were common to both control strain datasets. | ||
| Reference | WBPaper00048567 | ||
| Microarray_results (240) | |||
| Gene (231) | |||
| Attribute_of | Microarray_experiment | ||
| Regulation | Regulated_by_gene | WBGene00001032 | |
| Associated_with | Life_stage | WBls:0000065 |
