WormBase Tree Display for Gene: WBGene00015608

WBGene00015608 SMap: S_parent: Sequence: CHROMOSOME_II
  Identity: Version: 2
    Name: CGC_name: math-3 Person_evidence: WBPerson655
      Sequence_name: C08F1.4
      Molecular_name: C08F1.4a
        C08F1.4a.1
        CE27059
        C08F1.4b
        CE31771
        C08F1.4a.2
        C08F1.4a.3
        C08F1.4b.1
      Other_name: CELE_C08F1.4 Accession_evidence: NDB BX284602
      Public_name: math-3
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:56 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 12 Dec 2005 17:54:47 WBPerson2970 Name_change: CGC_name: math-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: math
    Allele (288)
    RNASeq_FPKM (74)
    Ortholog (20)
    Paralog (85)
    Structured_description: Concise_description: The C08F1.4 gene encodes a protein closely similar to F36H5.2, which has a meprin-associated Traf homology (MATH) domain and may be involved in apoptosis. Paper_evidence: WBPaper00004589
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enriched in head mesodermal cell; intestine; mechanosensory neurons; and pharyngeal muscle cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Ethanol; rotenone; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C08F1.4a
      C08F1.4b
    Corresponding_transcript: C08F1.4a.1
      C08F1.4a.2
      C08F1.4a.3
      C08F1.4b.1
    Associated_feature: WBsf220876
  Experimental_info: RNAi_result: WBRNAi00040107 Inferred_automatically: RNAi_primary
      WBRNAi00001135 Inferred_automatically: RNAi_primary
      WBRNAi00028678 Inferred_automatically: RNAi_primary
      WBRNAi00010460 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1020625
      Expr1144181
      Expr2013412
      Expr2031646
    Drives_construct: WBCnstr00028716
    Construct_product: WBCnstr00028716
    Microarray_results (32)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:pharyngeal-muscle_embryo_enriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00041954:ethanol_upregulated
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00048988:neuron_expressed
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051257:Levamisole_upregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:stavudine_72h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053664:ins-11(tm1053)_downregulated
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053909:N2_vs_CB4856_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056073:R24_upregulated_nhr-86_dependent
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056284:ints-4(RNAi)_downregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057068:ints-4(RNAi)_downregulated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061340:PLM
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061466:nath-10(icb99)_upregulated
      WBPaper00061527:nhr-107_19485-nhr-109_3743
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062440:crh-1(syb385)_downregulated
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:N2_N.ausubeli_regulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065623:28
      WBPaper00065623:51
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      cgc4489_group_7
      WBPaper00025099:NI_specific
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00029437:rde-4_upregulated
      WBPaper00031832:slr-2_regulated
      WBPaper00032948:StarveUp2
      WBPaper00034739:N2moreDR1350
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036286:Pattern_I
      WBPaper00039851:HK_C_albicans_vs_HK_OP50
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041211:RPW-24_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-exposed_3h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00053688:E.faecalis_upregulated
      WBPaper00053688:E.faecium_upregulated
      [cgc6390]:Cluster_A
      [cgc6390]:Cluster_B
      [cgc6390]:herm_soma-enriched
    SAGE_tag: SAGE:ttaaaatttt Strand: Sense
        Unambiguously_mapped
      SAGE:aacatttgat Strand: Antisense
      SAGE:gttgaagaat Strand: Sense
        Unambiguously_mapped
      SAGE:aaaattttaa Strand: Antisense
      SAGE:aagccagtat Strand: Sense
        Unambiguously_mapped
      SAGE:gaggatttcc Strand: Sense
        Unambiguously_mapped
      SAGE:gaatgtcgtaccattct Strand: Antisense
      SAGE:gaggatagag Strand: Sense
        Unambiguously_mapped
      SAGE:tcgttccatt Strand: Antisense
      SAGE:gagcatcaca Strand: Antisense
    Interaction: WBInteraction000103376
      WBInteraction000111941
      WBInteraction000194290
      WBInteraction000304440
      WBInteraction000307054
      WBInteraction000308208
      WBInteraction000365293
      WBInteraction000379544
      WBInteraction000387005
      WBInteraction000387576
      WBInteraction000396687
      WBInteraction000407608
      WBInteraction000428595
      WBInteraction000431203
      WBInteraction000462499
      WBInteraction000585445
  Map_info: Map: II Position: -14.4399 Error: 0.005013
    Positive: Positive_clone: C08F1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene