WormBase Tree Display for Gene: WBGene00003026

WBGene00003026 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: C12C8
  Identity: Version: 2
    Name: CGC_name: lin-41 Person_evidence: WBPerson261
      Sequence_name: C12C8.3
      Molecular_name: C12C8.3a
        C12C8.3a.1
        CE27062
        C12C8.3b
        CE27063
        C12C8.3a.2
        C12C8.3b.1
        C12C8.3b.2
      Other_name: lin-41A Accession_evidence: EMBL AF195610
        lin-41B Accession_evidence: EMBL AF195611
        lep-1 Person_evidence: WBPerson178
        CELE_C12C8.3 Accession_evidence: NDB BX284601
      Public_name: lin-41
    DB_info: Database: AceView gene 1J912
        WormQTL gene WBGene00003026
        WormFlux gene WBGene00003026
        NDB locus_tag CELE_C12C8.3
        Panther gene CAEEL|WormBase=WBGene00003026|UniProtKB=Q9U489
          family PTHR24104
        NCBI gene 172760
        RefSeq protein NM_001025828.7
            NM_001025827.6
        SwissProt UniProtAcc Q9U489
        UniProt_GCRP UniProtAcc Q9U489
        OMIM gene 618570
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:30 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 24 Aug 2005 11:43:48 WBPerson2970 Event: Acquires_merge: WBGene00002277
              Name_change: Other_name: lep-1
      Acquires_merge: WBGene00002277
    Status: Live
  Gene_info (12)
  Disease_info: Potential_model: DOID:10908 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:32669)
  Molecular_info: Corresponding_CDS: C12C8.3a
      C12C8.3b
    Corresponding_CDS_history: C12C8.3:wp47
    Corresponding_transcript: C12C8.3a.1
      C12C8.3a.2
      C12C8.3b.1
      C12C8.3b.2
    Other_sequence: AF195610
      AF195611
      Dviv_isotig12438
      JI165183.1
      Acan_isotig20235
      Acan_isotig08095
      CRC06076_1
      Oden_isotig18608
    Associated_feature (11)
    Transcription_factor: WBTranscriptionFactor000740
  Experimental_info: RNAi_result (64)
    Expr_pattern (13)
    Drives_construct (11)
    Construct_product: WBCnstr00005481
      WBCnstr00005483
      WBCnstr00008154
      WBCnstr00017544
      WBCnstr00017545
      WBCnstr00018650
      WBCnstr00019726
      WBCnstr00019727
      WBCnstr00036277
    Regulate_expr_cluster: WBPaper00050717:let-7(n2853)_lin-41(xe11)_downregulated
      WBPaper00050717:let-7(n2853)_lin-41(xe11)_upregulated
      WBPaper00051310:LIN-41_interacting
    Antibody: WBAntibody00002538
      WBAntibody00002566
      WBAntibody00002567
      WBAntibody00002954
    Microarray_results (26)
    Expression_cluster: WBPaper00027057:DCR-1_interacting_adult
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032425:up_in_zfp-1
      WBPaper00036291:ung-1_regulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00041071:spe-44_upregulated
      WBPaper00042165:let-7_upregulated
      WBPaper00044037:eat-2_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00044786:emr-1(gk119)_downregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045257:bar-1(ga80)_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Oogenic
      WBPaper00045618:fbf-1_downregulated
      WBPaper00045618:puf-8_downregulated
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00046012:tdp-1(ok803)_downregulated
      WBPaper00046338:intestine_unique
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046509:htz-1(ok3099)_downregulated
      WBPaper00048971:daf-16(mgDf50)_upregulated_L1
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049626:UNC-75_target
      WBPaper00049920:Glucose-Diet_downregulated_N2
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00049954:BPS_downregulated
      WBPaper00050225:flp-6(RNAi)_upregulated
      WBPaper00050412:cco-1(RNAi)_upregulated_N2
      WBPaper00050468:hlh-30-dependent_Cry5B_regulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050717:let-7(n2853)_lin-41(xe11)_upregulated
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051265:F1_morc-1(tm6048)_downregulated
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00051310:LIN-41_interacting
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(icb38)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053321:embryo-to-L1_upregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
      WBPaper00053814:25C_downregulated_PY79
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Metformin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055364:uaf-1(n4588)_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055804:FBF-1-FBF-2-associated_oogenic-enriched
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056284:ints-5(RNAi)_downregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056293:rpl-5(0)-rpl-33(0)_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00057154:HeatShock_downregulated_mRNA
      WBPaper00057154:HeatShock_upregulated_miRNA-target
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00058948:PA14_upregulated
      WBPaper00058969:RIS_enriched
      WBPaper00059027:neuron-synapses_enriched
      WBPaper00059254:CSR-1_interacting
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059471:EGL-43_interacting
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00059728:5ug_cholesterol_downregulated
      WBPaper00059728:20ug_cholesterol_downregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_L4
      WBPaper00059754:C.neoformans_H99_upregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00060100:SiNP_upregulated_mRNA
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:HB101_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061045:Y56A3A.22(cck200)_downregulated
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061466:nath-10(icb102)_downregulated
      WBPaper00061527:dld-1-skn-1_16701
      WBPaper00061527:tars-1-AFFX-r2-3026-5_at
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062118:neural-HSF-1_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062440:crh-1(n3315)_upregulated
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064122:vulva_transcriptome
      WBPaper00064163:ZNFX-1_interacting_young-adult
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064502:spe-44(fx110)_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064871:hypoxia_upregulated_F2
      WBPaper00065074:glna(-)_upregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_20C
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:Doxorubicin_downregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066118:cyclobutrifluram_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_12
      WBPaper00027111:rrf-2(ok210)_upregulated
      WBPaper00029437:dcr-1_downregulated
      WBPaper00031832:slr-2_regulated
      WBPaper00034661:AgNPs_downregulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00040821:Au-NP_regulated
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045263:ProLongevity-mtROS_upregulated
      WBPaper00045673:colistin_downregulated
      WBPaper00046083:pmk-1(km25)_OP50_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00056330:mrps-5(RNAi)_downregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc6390]:Cluster_E
      [cgc6390]:oogenesis-enriched
    Interaction: WBInteraction000001056
      WBInteraction000001057
      WBInteraction000001392
      WBInteraction000001408
      WBInteraction000001447
      WBInteraction000001461
      WBInteraction000001576
      WBInteraction000001578
      WBInteraction000002109
      WBInteraction000002112
      WBInteraction000002113
      WBInteraction000002118
      WBInteraction000002119
      WBInteraction000002140
      WBInteraction000002218
      WBInteraction000002556
      WBInteraction000002617
      WBInteraction000002772
      WBInteraction000002919
      WBInteraction000002920
      WBInteraction000002977
      WBInteraction000003295
      WBInteraction000003311
      WBInteraction000003314
      WBInteraction000003328
      WBInteraction000003337
      WBInteraction000003364
      WBInteraction000003448
      WBInteraction000003451
      WBInteraction000003469
      WBInteraction000003731
      WBInteraction000003737
      WBInteraction000003756
      WBInteraction000003779
      WBInteraction000003826
      WBInteraction000003977
      WBInteraction000003999
      WBInteraction000004000
      WBInteraction000004065
      WBInteraction000004074
      WBInteraction000004076
      WBInteraction000004109
      WBInteraction000004945
      WBInteraction000004981
      WBInteraction000005083
      WBInteraction000005371
      WBInteraction000005487
      WBInteraction000005699
      WBInteraction000005700
      WBInteraction000008489
      WBInteraction000009111
      WBInteraction000028360
      WBInteraction000028421
      WBInteraction000029202
      WBInteraction000029284
      WBInteraction000029780
      WBInteraction000050613
      WBInteraction000051441
      WBInteraction000051442
      WBInteraction000052093
      WBInteraction000052094
      WBInteraction000052687
      WBInteraction000052710
      WBInteraction000052868
      WBInteraction000149285
      WBInteraction000165138
      WBInteraction000166011
      WBInteraction000166012
      WBInteraction000227764
      WBInteraction000248036
      WBInteraction000249630
      WBInteraction000258292
      WBInteraction000306855
      WBInteraction000352705
      WBInteraction000362021
      WBInteraction000394928
      WBInteraction000500120
      WBInteraction000500121
      WBInteraction000500122
      WBInteraction000500896
      WBInteraction000500918
      WBInteraction000501097
      WBInteraction000501099
      WBInteraction000501101
      WBInteraction000501103
      WBInteraction000501105
      WBInteraction000501107
      WBInteraction000501109
      WBInteraction000501111
      WBInteraction000501113
      WBInteraction000501115
      WBInteraction000501117
      WBInteraction000501119
      WBInteraction000501121
      WBInteraction000501123
      WBInteraction000501125
      WBInteraction000501127
      WBInteraction000501129
      WBInteraction000501131
      WBInteraction000501133
      WBInteraction000501135
      WBInteraction000501137
      WBInteraction000501139
      WBInteraction000501141
      WBInteraction000501143
      WBInteraction000501145
      WBInteraction000501147
      WBInteraction000501149
      WBInteraction000501151
      WBInteraction000501153
      WBInteraction000501155
      WBInteraction000501157
      WBInteraction000501159
      WBInteraction000501161
      WBInteraction000501163
      WBInteraction000501165
      WBInteraction000501167
      WBInteraction000501169
      WBInteraction000501171
      WBInteraction000501173
      WBInteraction000501175
      WBInteraction000501177
      WBInteraction000501179
      WBInteraction000501181
      WBInteraction000501183
      WBInteraction000502201
      WBInteraction000503481
      WBInteraction000503485
      WBInteraction000503677
      WBInteraction000517887
      WBInteraction000517888
      WBInteraction000517889
      WBInteraction000518177
      WBInteraction000520005
      WBInteraction000520014
      WBInteraction000520060
      WBInteraction000521366
      WBInteraction000521367
      WBInteraction000521372
      WBInteraction000521398
      WBInteraction000521399
      WBInteraction000521975
      WBInteraction000522943
      WBInteraction000522969
      WBInteraction000523008
      WBInteraction000523052
      WBInteraction000523088
      WBInteraction000523291
      WBInteraction000523428
      WBInteraction000523458
      WBInteraction000523478
      WBInteraction000523483
      WBInteraction000524231
      WBInteraction000524232
      WBInteraction000524233
      WBInteraction000524234
      WBInteraction000524402
      WBInteraction000524403
      WBInteraction000524495
      WBInteraction000524496
      WBInteraction000524497
      WBInteraction000525098
      WBInteraction000525099
      WBInteraction000525100
      WBInteraction000525212
      WBInteraction000540544
      WBInteraction000540557
      WBInteraction000540558
      WBInteraction000540559
      WBInteraction000540560
      WBInteraction000540561
      WBInteraction000540562
      WBInteraction000540563
      WBInteraction000540564
      WBInteraction000540565
      WBInteraction000540566
      WBInteraction000540567
      WBInteraction000540568
      WBInteraction000540569
      WBInteraction000540570
      WBInteraction000540571
      WBInteraction000540572
      WBInteraction000540573
      WBInteraction000540574
      WBInteraction000540575
      WBInteraction000540576
      WBInteraction000540577
      WBInteraction000540578
      WBInteraction000540579
      WBInteraction000540580
      WBInteraction000540581
      WBInteraction000540582
      WBInteraction000540583
      WBInteraction000540584
      WBInteraction000540585
      WBInteraction000540586
      WBInteraction000540587
      WBInteraction000540588
      WBInteraction000540589
      WBInteraction000540590
      WBInteraction000540591
      WBInteraction000540592
      WBInteraction000540593
      WBInteraction000540594
      WBInteraction000540595
      WBInteraction000540596
      WBInteraction000540597
      WBInteraction000540598
      WBInteraction000540599
      WBInteraction000540600
      WBInteraction000540601
      WBInteraction000540602
      WBInteraction000540603
      WBInteraction000540604
      WBInteraction000540605
      WBInteraction000540687
      WBInteraction000541130
      WBInteraction000541133
      WBInteraction000541746
      WBInteraction000543406
      WBInteraction000543798
      WBInteraction000543822
      WBInteraction000548999
      WBInteraction000550241
      WBInteraction000550336
      WBInteraction000550337
      WBInteraction000550338
      WBInteraction000550339
      WBInteraction000550340
      WBInteraction000550341
      WBInteraction000550342
      WBInteraction000550343
      WBInteraction000550344
      WBInteraction000550345
      WBInteraction000550346
      WBInteraction000550347
      WBInteraction000550348
      WBInteraction000550349
      WBInteraction000550350
      WBInteraction000550351
      WBInteraction000550352
      WBInteraction000550353
      WBInteraction000550354
      WBInteraction000550355
      WBInteraction000550356
      WBInteraction000550357
      WBInteraction000550358
      WBInteraction000550359
      WBInteraction000550360
      WBInteraction000550361
      WBInteraction000550362
      WBInteraction000550363
      WBInteraction000550364
      WBInteraction000550365
      WBInteraction000550366
      WBInteraction000550367
      WBInteraction000550368
      WBInteraction000550369
      WBInteraction000555183
      WBInteraction000558195
      WBInteraction000558196
      WBInteraction000558197
      WBInteraction000558198
      WBInteraction000560065
      WBInteraction000565988
      WBInteraction000569758
      WBInteraction000570296
      WBInteraction000570673
      WBInteraction000586711
    WBProcess: WBbiopr:00000020
      WBbiopr:00000057
      WBbiopr:00000083
  Map_info: Map: I Position: 3.75248 Error: 0.000711
    Well_ordered
    Positive: Positive_clone: C12C8 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 3934
      Multi_point: 1445
        5072
        5602
        3193
        3194
        3195
        3196
        3197
        3198
        3199
      Pos_neg_data: 3935
        8519
        8520
        8521
        8522
        8523
        8524
        8525
  Reference (217)
  Remark: inx-20 and lep-1 has been merged in WS89 and unmerged in WS104 due to SNP mapping evidence. Unmerging also unlinks its other_name opu-20 which is an other_name of inx-20 Person_evidence: WBPerson178
  Method: Gene