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WormBase Tree Display for Gene: WBGene00015337

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Name Class

WBGene00015337SMapS_parentSequenceC02D5
IdentityVersion3
NameCGC_namegsto-2Paper_evidenceWBPaper00031042
Sequence_nameC02D5.3
Molecular_nameC02D5.3
C02D5.3.1
CE39555
Other_nameCELE_C02D5.3Accession_evidenceNDBBX284603
Public_namegsto-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:55WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
230 Oct 2007 09:48:36WBPerson2970Name_changeCGC_namegsto-2
329 Apr 2010 11:32:38WBPerson1867EventSplit_intoWBGene00043097
Split_intoWBGene00043097
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgsto
Allele (21)
In_clusterconserved_RDE-1_cluster
RNASeq_FPKM (74)
GO_annotation00041253
00041254
00041255
00041256
00041257
00041258
00041259
00041260
00041261
00041262
00041263
00041264
00041265
00041266
00041267
00121257
00121258
Ortholog (34)
ParalogWBGene00001792Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00016204Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00043097Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00019636Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00001365Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001371Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001790Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001791Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00008920Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00021817Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionC02D5.3 is predicted to encode, by alternative splicing and an internal promoter, three partially non-overlapping putative omega-class glutathione transferases (GST; EC 2.5.1.18) which, like their paralog GSTO-1, might have thiol oxidoreductase and dehydroascorbate reductase activity; other C02D5.3 paralogs include GST-44 and K10F12.4; C02D5.3 has no obvious function in mass RNAi assays.Paper_evidenceWBPaper00031042
WBPaper00031083
Curator_confirmedWBPerson567
Date_last_updated16 Oct 2007 00:00:00
Automated_descriptionPredicted to enable glutathione dehydrogenase (ascorbate) activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in cytoplasm. Expressed in head; intestine; and tail. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and asthma. Is an ortholog of human GSTO1 (glutathione S-transferase omega 1) and GSTO2 (glutathione S-transferase omega 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:13312,HGNC:23064)
DOID:2841Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:23064)
DOID:14330Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:13312,HGNC:23064)
Molecular_infoCorresponding_CDSC02D5.3
Corresponding_CDS_historyC02D5.3:wp92
C02D5.3:wp102
C02D5.3:wp150
C02D5.3a:wp214
Corresponding_transcriptC02D5.3.1
Other_sequenceCBC03728_1
Associated_featureWBsf993393
WBsf225438
Experimental_infoRNAi_resultWBRNAi00005474Inferred_automaticallyRNAi_primary
WBRNAi00009988Inferred_automaticallyRNAi_primary
WBRNAi00039415Inferred_automaticallyRNAi_primary
WBRNAi00115491Inferred_automaticallyRNAi_primary
WBRNAi00005901Inferred_automaticallyRNAi_primary
WBRNAi00028343Inferred_automaticallyRNAi_primary
WBRNAi00115553Inferred_automaticallyRNAi_primary
Expr_patternExpr8013
Expr1027147
Expr1143530
Expr2012337
Expr2030574
Drives_constructWBCnstr00000768
WBCnstr00007146
WBCnstr00028922
Construct_productWBCnstr00028922
Microarray_results (21)
Expression_clusterWBPaper00024505:pharyngeal_enriched
WBPaper00038168:lin-15B(n744)_upregulated
WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
WBPaper00041075:hcf-1(-)_skn-1(+)_upregulated
WBPaper00042194:nhr-114(RNAi)_downregulated
WBPaper00042215:wdr-23(tm1817)_upregulated
WBPaper00044316:CH3HgCl_7.5uM_upregulated
WBPaper00044316:HgCl2_20uM_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00044743:wdr-23_neuron_upregulated
WBPaper00045417:128Q-huntingtin_upreglated
WBPaper00045918:120h_infection_recovery_upregulated
WBPaper00049377:MWCNT_downregulated
WBPaper00050332:skn-1(RNAi)_downregulated
WBPaper00050370:dpy-21(e428)_L3_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00051558:aging_regulated
WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
WBPaper00053402:cco-1(RNAi)_upregulated
WBPaper00053402:his-3(RNAi)_downregulated
WBPaper00053798:nhr-49(nr2041)_tBOOH_upregulated
WBPaper00053810:daf-2(e1370)_upregulated
WBPaper00053810:isp-1(qm150)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055013:hmg-3(bar24)_upregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055354:Rifampicin_upregulated
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00055944:C.butyricum_vs_OP50_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00057041:spc-1(cas971)_downregulated
WBPaper00057068:Cadmium_upregulated
WBPaper00058711:skn-1(lax188)_upregulated
WBPaper00059231:alh-6(lax105)_D3Adult_upregulated
WBPaper00059253:stearic-acid_upregulated
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059754:E.faecalis_OG1RF_upregulated
WBPaper00060399:CoCl2_6hr_upregulated_N2
WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
WBPaper00060445:ikb-1(nr2027)_downregulated_L4
WBPaper00060445:nfki-1(cer1)_downregulated_L4
WBPaper00060661:sensory-neuron_enriched
WBPaper00061081:E.faecalis_upregulated_N2
WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
WBPaper00061340:hmc_and_homolog
WBPaper00061341:28C_48h_upregulated
WBPaper00061527:F55G11.8-dod-17
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062345:bortezomib_4h_upregulated_N2
WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
WBPaper00064005:starvation_upregulated_N2_mRNA
WBPaper00064130:Beta-Amyloid_24h_downregulated_mRNA
WBPaper00064509:static-magnetic-field_downregulated
WBPaper00064532:pals-25(icb98)_downregulated
WBPaper00064637:cox-5B(RNAi)_upregulated
WBPaper00064716:paraquat_downregulated
WBPaper00064788:ketamine_upregulated
WBPaper00065029:cadmium_upregulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065841:38_0
WBPaper00065841:38_1
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066062:xrep-4(lax137)_upregulated
cgc4489_group_24
WBPaper00031003:24hr_muscle_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00031184:acrylamide_upregulated
WBPaper00034757:up_by_oxidative_stress
WBPaper00045015:acs-3(ft5)_downregulated
WBPaper00045015:nhr-25(RNAi)_downregulated
WBPaper00047070:N2_starvation_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
WBPaper00055899:2,4-Dinitroanisole_regulated
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
InteractionWBInteraction000155859
WBInteraction000207450
WBInteraction000436163
WBInteraction000473816
WBInteraction000524297
WBInteraction000550278
Map_infoMapIIIPosition-0.250997Error0.001097
PositivePositive_cloneC02D5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00031184
WBPaper00038491
WBPaper00055090
WBPaper00062515
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene