WormBase Tree Display for Gene: WBGene00019636

WBGene00019636 SMap: S_parent: Sequence: K10F12
  Identity: Version: 2
    Name: CGC_name: gsto-3
      Sequence_name: K10F12.4
      Molecular_name: K10F12.4a
        K10F12.4a.1
        CE12092
        K10F12.4b
        CE31038
        K10F12.4b.1
      Other_name: CELE_K10F12.4 Accession_evidence: NDB BX284603
      Public_name: gsto-3
    DB_info: Database: AceView gene 3A986
        WormQTL gene WBGene00019636
        WormFlux gene WBGene00019636
        NDB locus_tag CELE_K10F12.4
        Panther gene CAEEL|WormBase=WBGene00019636|UniProtKB=O17234
          family PTHR43968
        NCBI gene 175196
        RefSeq protein NM_001393255.1
            NM_171061.1
        TREEFAM TREEFAM_ID TF105325
        TrEMBL UniProtAcc O17234
            Q8IA74
        UniProt_GCRP UniProtAcc O17234
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 30 Oct 2007 09:50:31 WBPerson2970 Name_change: CGC_name: gsto-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gsto
    Allele (64)
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (38)
    Paralog: WBGene00001792 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00015337 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00016204 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00043097 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00001365 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001371 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001790 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001791 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00008920 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00021817 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: K10F12.4 encodes, by alternative splicing, one isoform of a putative omega-class glutathione transferase (GST; EC 2.5.1.18) which, like its paralog GSTO-1, might have thiol oxidoreductase and dehydroascorbate reductase activity; other K10F12.4 paralogs include GST-44 and C02D5.3; K10F12.4 has no obvious function in mass RNAi assays. Paper_evidence: WBPaper00031042
            WBPaper00031083
          Curator_confirmed: WBPerson567
          Date_last_updated: 16 Oct 2007 00:00:00
      Automated_description: Predicted to enable glutathione dehydrogenase (ascorbate) activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and asthma. Is an ortholog of human GSTO1 (glutathione S-transferase omega 1) and GSTO2 (glutathione S-transferase omega 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13312,HGNC:23064)
      DOID:2841 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:23064)
      DOID:14330 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13312,HGNC:23064)
  Molecular_info: Corresponding_CDS: K10F12.4a
      K10F12.4b
    Corresponding_transcript: K10F12.4a.1
      K10F12.4b.1
    Other_sequence (28)
    Associated_feature: WBsf666518
      WBsf226098
  Experimental_info: RNAi_result: WBRNAi00050549 Inferred_automatically: RNAi_primary
      WBRNAi00006697 Inferred_automatically: RNAi_primary
      WBRNAi00016984 Inferred_automatically: RNAi_primary
      WBRNAi00034265 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1028100
      Expr1038480
      Expr1154252
      Expr2012338
      Expr2030575
    Microarray_results (22)
    Expression_cluster (128)
    Interaction (55)
  Map_info: Map: III Position: -26.8824 Error: 0.003615
    Positive: Positive_clone: K10F12 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene