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WormBase Tree Display for Gene: WBGene00015337

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Name Class

WBGene00015337SMapS_parentSequenceC02D5
IdentityVersion3
NameCGC_namegsto-2Paper_evidenceWBPaper00031042
Sequence_nameC02D5.3
Molecular_nameC02D5.3
C02D5.3.1
CE39555
Other_nameCELE_C02D5.3Accession_evidenceNDBBX284603
Public_namegsto-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:55WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
230 Oct 2007 09:48:36WBPerson2970Name_changeCGC_namegsto-2
329 Apr 2010 11:32:38WBPerson1867EventSplit_intoWBGene00043097
Split_intoWBGene00043097
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgsto
Allele (21)
In_clusterconserved_RDE-1_cluster
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (34)
ParalogWBGene00001792Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00016204Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00043097Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00019636Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00001365Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001371Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001790Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001791Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00008920Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00021817Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionC02D5.3 is predicted to encode, by alternative splicing and an internal promoter, three partially non-overlapping putative omega-class glutathione transferases (GST; EC 2.5.1.18) which, like their paralog GSTO-1, might have thiol oxidoreductase and dehydroascorbate reductase activity; other C02D5.3 paralogs include GST-44 and K10F12.4; C02D5.3 has no obvious function in mass RNAi assays.Paper_evidenceWBPaper00031042
WBPaper00031083
Curator_confirmedWBPerson567
Date_last_updated16 Oct 2007 00:00:00
Automated_descriptionPredicted to enable glutathione dehydrogenase (ascorbate) activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in cytoplasm. Expressed in head; intestine; and tail. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and asthma. Is an ortholog of human GSTO1 (glutathione S-transferase omega 1) and GSTO2 (glutathione S-transferase omega 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:13312,HGNC:23064)
DOID:2841Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:23064)
DOID:14330Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:13312,HGNC:23064)
Molecular_infoCorresponding_CDSC02D5.3
Corresponding_CDS_historyC02D5.3:wp92
C02D5.3:wp102
C02D5.3:wp150
C02D5.3a:wp214
Corresponding_transcriptC02D5.3.1
Other_sequenceCBC03728_1
Associated_featureWBsf993393
WBsf225438
Experimental_infoRNAi_resultWBRNAi00005474Inferred_automaticallyRNAi_primary
WBRNAi00009988Inferred_automaticallyRNAi_primary
WBRNAi00039415Inferred_automaticallyRNAi_primary
WBRNAi00115491Inferred_automaticallyRNAi_primary
WBRNAi00005901Inferred_automaticallyRNAi_primary
WBRNAi00028343Inferred_automaticallyRNAi_primary
WBRNAi00115553Inferred_automaticallyRNAi_primary
Expr_patternExpr8013
Expr1027147
Expr1143530
Expr2012337
Expr2030574
Drives_constructWBCnstr00000768
WBCnstr00007146
WBCnstr00028922
Construct_productWBCnstr00028922
Microarray_results (21)
Expression_cluster (87)
InteractionWBInteraction000155859
WBInteraction000207450
WBInteraction000436163
WBInteraction000473816
WBInteraction000524297
WBInteraction000550278
Map_infoMapIIIPosition-0.250997Error0.001097
PositivePositive_cloneC02D5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00031184
WBPaper00038491
WBPaper00055090
WBPaper00062515
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene