WormBase Tree Display for Gene: WBGene00015337

WBGene00015337 SMap: S_parent: Sequence: C02D5
  Identity: Version: 3
    Name: CGC_name: gsto-2 Paper_evidence: WBPaper00031042
      Sequence_name: C02D5.3
      Molecular_name: C02D5.3
        C02D5.3.1
        CE39555
      Other_name: CELE_C02D5.3 Accession_evidence: NDB BX284603
      Public_name: gsto-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 30 Oct 2007 09:48:36 WBPerson2970 Name_change: CGC_name: gsto-2
        3 29 Apr 2010 11:32:38 WBPerson1867 Event: Split_into: WBGene00043097
      Split_into: WBGene00043097
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gsto
    Allele (21)
    In_cluster: conserved_RDE-1_cluster
    RNASeq_FPKM (74)
    GO_annotation (17)
    Ortholog: WBGene00037589 Caenorhabditis briggsae From_analysis: OrthoMCL
            Inparanoid_8
      WBGene00151112 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00061809 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00207330 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
      WBGene00179684 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00104982 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00095142 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00231118 Brugia malayi From_analysis: WormBase-Compara
      WBGene00268528 Brugia malayi From_analysis: WormBase-Compara
      CSP29.g20039 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP32.g12029 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP39.g15870 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g03470 Oscheius tipulae From_analysis: WormBase-Compara
      WBGene00245342 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00245344 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00245474 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00249045 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00249046 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00249047 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00272214 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00273146 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00289439 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0035904 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0086348 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0035906 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0035907 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-040718-365 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-041114-67 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:13312 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:23064 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1342273 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1915464 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:70952 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1310764 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00001792 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00016204 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00043097 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00019636 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00001365 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001371 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001790 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001791 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00008920 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00021817 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: C02D5.3 is predicted to encode, by alternative splicing and an internal promoter, three partially non-overlapping putative omega-class glutathione transferases (GST; EC 2.5.1.18) which, like their paralog GSTO-1, might have thiol oxidoreductase and dehydroascorbate reductase activity; other C02D5.3 paralogs include GST-44 and K10F12.4; C02D5.3 has no obvious function in mass RNAi assays. Paper_evidence: WBPaper00031042
            WBPaper00031083
          Curator_confirmed: WBPerson567
          Date_last_updated: 16 Oct 2007 00:00:00
      Automated_description: Predicted to enable glutathione dehydrogenase (ascorbate) activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in cytoplasm. Expressed in head; intestine; and tail. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and asthma. Is an ortholog of human GSTO1 (glutathione S-transferase omega 1) and GSTO2 (glutathione S-transferase omega 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13312,HGNC:23064)
      DOID:2841 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:23064)
      DOID:14330 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13312,HGNC:23064)
  Molecular_info: Corresponding_CDS: C02D5.3
    Corresponding_CDS_history: C02D5.3:wp92
      C02D5.3:wp102
      C02D5.3:wp150
      C02D5.3a:wp214
    Corresponding_transcript: C02D5.3.1
    Other_sequence: CBC03728_1
    Associated_feature: WBsf993393
      WBsf225438
  Experimental_info: RNAi_result: WBRNAi00005474 Inferred_automatically: RNAi_primary
      WBRNAi00009988 Inferred_automatically: RNAi_primary
      WBRNAi00039415 Inferred_automatically: RNAi_primary
      WBRNAi00115491 Inferred_automatically: RNAi_primary
      WBRNAi00005901 Inferred_automatically: RNAi_primary
      WBRNAi00028343 Inferred_automatically: RNAi_primary
      WBRNAi00115553 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr8013
      Expr1027147
      Expr1143530
      Expr2012337
      Expr2030574
    Drives_construct: WBCnstr00000768
      WBCnstr00007146
      WBCnstr00028922
    Construct_product: WBCnstr00028922
    Microarray_results (21)
    Expression_cluster (87)
    Interaction: WBInteraction000155859
      WBInteraction000207450
      WBInteraction000436163
      WBInteraction000473816
      WBInteraction000524297
      WBInteraction000550278
  Map_info: Map: III Position: -0.250997 Error: 0.001097
    Positive: Positive_clone: C02D5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00031184
    WBPaper00038491
    WBPaper00055090
    WBPaper00062515
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene