WormBase Tree Display for Gene: WBGene00003732

WBGene00003732 SMap: S_parent: Sequence: F14B8
  Identity: Version: 1
    Name: CGC_name: nhx-4
      Sequence_name: F14B8.1
      Molecular_name: F14B8.1a
        F14B8.1a.1
        CE30951
        F14B8.1b
        CE02644
        F14B8.1b.1
      Other_name: CELE_F14B8.1 Accession_evidence: NDB BX284606
      Public_name: nhx-4
    DB_info: Database: AceView gene XH539
        WormQTL gene WBGene00003732
        WormFlux gene WBGene00003732
        NDB locus_tag CELE_F14B8.1
        Panther gene CAEEL|WormBase=WBGene00003732|UniProtKB=G5EDU2
          family PTHR10110
        NCBI gene 180964
        RefSeq protein NM_001029391.5
            NM_001381015.2
        TREEFAM TREEFAM_ID TF317212
        TrEMBL UniProtAcc G5ECB7
            G5EDU2
        UniProt_GCRP UniProtAcc G5EDU2
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:32 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nhx
    Allele: WBVar01498964
      WBVar01882364
      WBVar00507228
      WBVar01882365
      WBVar01882366
      WBVar01882367
      WBVar01882368
      WBVar01882369
      WBVar01882370
      WBVar01882371
      WBVar01882372
      WBVar01882373
      WBVar01882374
      WBVar01882375
      WBVar01882376
      WBVar01882377
      WBVar01882378
      WBVar01882379
      WBVar01882380
      WBVar01882381
      WBVar01882382
      WBVar01882383
      WBVar01882384
      WBVar00303752
      WBVar01882385
      WBVar00303753
      WBVar01882386
      WBVar01882387
      WBVar01882388
      WBVar01882389
      WBVar01882390
      WBVar01882391
      WBVar01882392
      WBVar01882393
      WBVar01882394
      WBVar01882395
      WBVar01882396
      WBVar01882397
      WBVar01882398
      WBVar01882399
      WBVar01882400
      WBVar01882401
      WBVar01882402
      WBVar01882403
      WBVar01882404
      WBVar01882405
      WBVar01882406
      WBVar01882407
      WBVar02064512
      WBVar01882408
      WBVar01882409
      WBVar02064513
      WBVar02064514
      WBVar01882410
      WBVar02064515
      WBVar01882411
      WBVar01882412
      WBVar02064516
      WBVar02064517
      WBVar01882413
      WBVar01882414
      WBVar02064518
      WBVar01882415
      WBVar02064519
      WBVar02050634
      WBVar02064520
      WBVar01882416
      WBVar01882417
      WBVar02064521
      WBVar02064522
      WBVar01882418
      WBVar01882419
      WBVar02064523
      WBVar01882420
      WBVar02064524
      WBVar02064525
      WBVar01882421
      WBVar01882422
      WBVar01882423
      WBVar01882424
      WBVar01882425
      WBVar00080156
      WBVar01882426
      WBVar00080157
      WBVar00080158
      WBVar00080161
      WBVar00080163
      WBVar00080164
      WBVar02032737
      WBVar01897637
      WBVar01469536
      WBVar00317105
      WBVar02116457
      WBVar02139510
      WBVar01469538
      WBVar02116458
      WBVar01469539
      WBVar02116459
      WBVar01469540
      WBVar01469543
      WBVar02116460
      WBVar01469544
      WBVar02116461
      WBVar01469545
      WBVar02116462
      WBVar01469546
      WBVar02116463
      WBVar01820169
      WBVar00035311
      WBVar01927073
      WBVar00142364
      WBVar01927074
      WBVar01927075
      WBVar01157407
      WBVar00035316
      WBVar01927076
      WBVar01157408
      WBVar01157409
      WBVar00035321
      WBVar01157410
      WBVar01157411
      WBVar01157412
      WBVar01157413
      WBVar00035326
      WBVar01157414
      WBVar01157415
      WBVar00035331
      WBVar01157416
      WBVar01157417
      WBVar01157418
      WBVar00035336
      WBVar01157419
      WBVar01157420
      WBVar01157421
      WBVar01157422
      WBVar01157423
      WBVar01157424
      WBVar00236103
      WBVar01157425
      WBVar01901562
      WBVar01157426
      WBVar00236104
      WBVar01157427
      WBVar01157428
      WBVar01157429
      WBVar01157430
      WBVar01157431
      WBVar01157432
      WBVar01157433
      WBVar01157434
      WBVar01157435
      WBVar01497455
      WBVar01157436
      WBVar01157437
      WBVar01157438
      WBVar01157439
      WBVar01157440
      WBVar01157441
      WBVar01157442
      WBVar01157443
      WBVar01157444
      WBVar01157445
      WBVar01157446
      WBVar01157447
      WBVar01157448
      WBVar01157449
      WBVar00091952
      WBVar01157450
      WBVar01157451
      WBVar01157452
      WBVar01848973
      WBVar01157453
      WBVar01848974
      WBVar01157454
      WBVar01848975
      WBVar01848976
      WBVar01157455
      WBVar01157456
      WBVar01848977
      WBVar01157457
      WBVar00507220
      WBVar00507221
      WBVar00507222
      WBVar00507223
      WBVar00507224
      WBVar00507225
      WBVar01882361
      WBVar00507226
      WBVar01882362
      WBVar01500067
      WBVar01882363
      WBVar00507227
    Strain: WBStrain00031554
    RNASeq_FPKM (74)
    GO_annotation (18)
    Ortholog (49)
    Paralog: WBGene00003729 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003730 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003731 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003736 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003733 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003735 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003734 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003943 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: nhx-4 encodes two isoforms of a sodium/proton exchanger expressed in the plasma membrane of nearly all cells and cell types; in polarized epithelial cells, NHX-4::GFP appears specifically located in the basolateral membrane, like human SLC9A1 ('NHE1'; OMIM:107310); nhx-4 has no reported mutant or RNAi phenotype, but, given its ubiquitous expression, may represent a housekeeping exchanger generally required for cellular viability; transgenic NHX-4A, when expressed in cell culture, mediates Na[+]-dependent pH recovery after intracellular acidification, independently of extracellular Cl[-]. Paper_evidence (2)
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to be located in plasma membrane. Expressed widely. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F14B8.1a
      F14B8.1b
    Corresponding_transcript: F14B8.1a.1
      F14B8.1b.1
    Other_sequence: Oden_isotig18970
      CBC14254_1
      Dviv_isotig16028
      Dviv_isotig16027
      Acan_isotig07819
    Associated_feature: WBsf662927
      WBsf718617
      WBsf1005679
      WBsf1005680
      WBsf1005681
      WBsf235886
      WBsf235887
      WBsf235888
  Experimental_info: RNAi_result: WBRNAi00086171 Inferred_automatically: RNAi_primary
      WBRNAi00086174 Inferred_automatically: RNAi_primary
      WBRNAi00044576 Inferred_automatically: RNAi_primary
      WBRNAi00030927 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2244
      Expr1021689
      Expr1031743
      Expr1148533
      Expr2014256
      Expr2032496
    Drives_construct: WBCnstr00010724
      WBCnstr00035909
    Construct_product: WBCnstr00010724
      WBCnstr00035909
    Microarray_results (26)
    Expression_cluster (98)
    Interaction: WBInteraction000134079
      WBInteraction000441533
  Map_info: Map: X Position: -2.00918 Error: 0.028616
    Positive: Positive_clone: F14B8 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4441
        4531
    Pseudo_map_position
  Reference: WBPaper00005421
    WBPaper00038491
    WBPaper00055090
  Remark: Sequence connection from [Nehrke K, Melvin J]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    nxh-2 nxh-3 nxh-4 nxh-5 nxh-6 nxh-7 nxh-8 nxh-9 published in cgc5421 actually refer to nhx genes CGC_data_submission
  Method: Gene