WormBase Tree Display for Gene: WBGene00000221
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| WBGene00000221 | SMap | S_parent | Sequence | T04C10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name (5) | |||||||||
| DB_info | Database | AceView | gene | XP428 | |||||
| WormQTL | gene | WBGene00000221 | |||||||
| WormFlux | gene | WBGene00000221 | |||||||
| NDB | locus_tag | CELE_T04C10.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000221|UniProtKB=Q22156 | |||||||
| family | PTHR13044 | ||||||||
| NCBI | gene | 181576 | |||||||
| RefSeq | protein | NM_001420580.1 | |||||||
| SwissProt | UniProtAcc | Q22156 | |||||||
| TREEFAM | TREEFAM_ID | TF318507 | |||||||
| UniProt_GCRP | UniProtAcc | Q22156 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 02 Mar 2018 11:09:16 | WBPerson4025 | Event | Split_into | WBGene00303075 | ||||
| 3 | 15 Jul 2019 14:29:07 | WBPerson1983 | Name_change | CGC_name | atf-4 | ||||
| Other_name | atf-5 | ||||||||
| Split_into | WBGene00303075 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | atf | ||||||||
| Allele | WBVar00091862 | Inferred_automatically | From strain object: RB790 | ||||||
| WBVar01210736 | |||||||||
| WBVar01210737 | |||||||||
| WBVar01210738 | |||||||||
| WBVar01499887 | |||||||||
| WBVar01499519 | |||||||||
| WBVar01210739 | |||||||||
| WBVar01210740 | |||||||||
| WBVar01499888 | |||||||||
| WBVar01210741 | |||||||||
| WBVar01210742 | |||||||||
| WBVar01210743 | |||||||||
| WBVar01210744 | |||||||||
| WBVar01210745 | |||||||||
| WBVar01499710 | |||||||||
| WBVar01553141 | |||||||||
| WBVar01210746 | |||||||||
| WBVar01210747 | |||||||||
| WBVar01210748 | |||||||||
| WBVar01210749 | |||||||||
| WBVar01210750 | |||||||||
| WBVar01760464 | |||||||||
| WBVar01788201 | |||||||||
| WBVar01545032 | |||||||||
| WBVar02140602 | |||||||||
| WBVar01573149 | |||||||||
| WBVar00252729 | |||||||||
| WBVar00525159 | |||||||||
| WBVar00525160 | |||||||||
| WBVar00525161 | |||||||||
| WBVar00525162 | |||||||||
| WBVar00525163 | |||||||||
| WBVar00313699 | |||||||||
| WBVar00313700 | |||||||||
| WBVar00313701 | |||||||||
| WBVar01704351 | |||||||||
| WBVar00085643 | |||||||||
| WBVar00085644 | |||||||||
| WBVar00296295 | |||||||||
| WBVar00085645 | |||||||||
| WBVar00085646 | |||||||||
| WBVar00085647 | |||||||||
| WBVar00085648 | |||||||||
| WBVar00085649 | |||||||||
| WBVar01981714 | |||||||||
| WBVar01602525 | |||||||||
| WBVar01602526 | |||||||||
| WBVar01602527 | |||||||||
| WBVar01498960 | |||||||||
| WBVar01210732 | |||||||||
| WBVar01210733 | |||||||||
| WBVar01210734 | |||||||||
| WBVar01500067 | |||||||||
| WBVar01210735 | |||||||||
| Strain | WBStrain00031503 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (24) | |||||||||
| Paralog | WBGene00012330 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00007932 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00013878 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00077761 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | atf-5 encodes a homolog of the mammalian bZIP transcription factors ATF4and ATF5, analogous to GCN4 in S. cerevisiae; like like ATF4 and GCN4,atf-5 has an extensive 5' UTR with one 37-residue uORF; ATF4 is poorlytranslated in unstressed cells but well-translated during ER stress, aminoacid starvation, or arsenite treatment; possibly atf-5 is alsotranslationally regulated in a way similar to ATF4. | Curator_confirmed | WBPerson567 | |||||
| Date_last_updated | 09 Aug 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in hydrogen sulfide biosynthetic process and positive regulation of gene expression. Located in nucleus. Human ortholog(s) of this gene implicated in prostate carcinoma. Is an ortholog of human ATF4 (activating transcription factor 4) and ATF5 (activating transcription factor 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10286 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:786) | ||||
| Molecular_info | Corresponding_CDS | T04C10.4 | |||||||
| Corresponding_CDS_history | T04C10.4a:wp264 | ||||||||
| T04C10.4b:wp264 | |||||||||
| Corresponding_transcript | T04C10.4.1 | ||||||||
| Other_sequence (24) | |||||||||
| Associated_feature | WBsf654606 | ||||||||
| WBsf978443 | |||||||||
| WBsf982291 | |||||||||
| WBsf1008012 | |||||||||
| WBsf1024465 | |||||||||
| WBsf238254 | |||||||||
| Transcription_factor | WBTranscriptionFactor000146 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00018131 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00035130 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000621 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00052365 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092892 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr11023 | ||||||||
| Expr1020406 | |||||||||
| Expr1030138 | |||||||||
| Expr1155993 | |||||||||
| Expr2009480 | |||||||||
| Expr2027717 | |||||||||
| Drives_construct (2) | |||||||||
| Construct_product | WBCnstr00017860 | ||||||||
| WBCnstr00037651 | |||||||||
| Regulate_expr_cluster | WBPaper00062518:atf-4_regulated | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (175) | |||||||||
| Interaction (27) | |||||||||
| Map_info | Map | X | Position | 21.3687 | Error | 0.007883 | |||
| Positive | Positive_clone | T04C10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4483 | |||||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
