Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Molecule: WBMol:00004565

expand all nodes | collapse all nodes | view schema

Name Class

WBMol:00004565Public_nameTunicamycin
SMILES[H][C@@](O)(C[C@H]1O[C@@H](OC2O[C@H]([*]O)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC([*])=O)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O
Synonymtunicamycin
DB_infoDatabaseNLM_MeSHUIDD014415
CTDChemicalIDD014415
ChEBICHEBI_ID29699
ChemIDplusRN11089-65-9
KEGG COMPOUNDAccession_numberC12063
WBProcessWBbiopr:00000046
WBbiopr:00000076
WBbiopr:00000079
Regulate_expr_clusterWBPaper00045390:tunicamycin_downregulated
WBPaper00045390:tunicamycin_upregulated
WBPaper00045971:tunicamycin_upregulated_control
WBPaper00045971:tunicamycin_upregulated_RtcB(null)
WBPaper00055482:Tunicamycin_downregulated
WBPaper00055482:Tunicamycin_upregulated
WBPaper00061853:tunicamycin_downregulated_N2
WBPaper00061853:tunicamycin_downregulated_osm-3(dh441)
WBPaper00061853:tunicamycin_upregulated_N2
WBPaper00061853:tunicamycin_upregulated_osm-3(dh441)
Affects_phenotype_ofVariation (20)
StrainWBStrain00034065WBPhenotype:0001834Paper_evidenceWBPaper00053292
Curator_confirmedWBPerson712
WBPhenotype:0000083Paper_evidenceWBPaper00053292
Curator_confirmedWBPerson712
WBPhenotype:0000757Paper_evidenceWBPaper00053292
Curator_confirmedWBPerson712
TransgeneWBTransgene00023641WBPhenotype:0002422Paper_evidenceWBPaper00042524
Curator_confirmedWBPerson2987
WBTransgene00023643WBPhenotype:0002422Paper_evidenceWBPaper00042524
Curator_confirmedWBPerson2987
WBTransgene00024958WBPhenotype:0002422Paper_evidenceWBPaper00048848
Curator_confirmedWBPerson17144
RNAi (249)
Disease_infoInduces_diseaseDOID:14330
Disease_model_inducerWBDOannot00000144
Interaction (40)
Molecule_useinhibits protein glycosylation/secretory pathway | induces ER-stress | inhibits asparagine-linked glycosylation | a natural compound that leads to the accumulation of unfolded proteins in the ER due to its inhibitory effect on N-linked protein glycosylation
ReferenceWBPaper00040397
WBPaper00040984
WBPaper00005044
WBPaper00026830
WBPaper00026929
WBPaper00031456
WBPaper00032192
WBPaper00032255
WBPaper00033126
WBPaper00041295