WormBase Tree Display for Molecule: WBMol:00004565
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WBMol:00004565 | Public_name | Tunicamycin | ||||
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SMILES | [H][C@@](O)(C[C@H]1O[C@@H](OC2O[C@H]([*]O)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC([*])=O)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O | |||||
Synonym | tunicamycin | |||||
DB_info | Database | NLM_MeSH | UID | D014415 | ||
CTD | ChemicalID | D014415 | ||||
ChEBI | CHEBI_ID | 29699 | ||||
ChemIDplus | RN | 11089-65-9 | ||||
KEGG COMPOUND | Accession_number | C12063 | ||||
WBProcess | WBbiopr:00000046 | |||||
WBbiopr:00000076 | ||||||
WBbiopr:00000079 | ||||||
Regulate_expr_cluster (10) | ||||||
Affects_phenotype_of | Variation (20) | |||||
Strain | WBStrain00034065 | WBPhenotype:0001834 | Paper_evidence | WBPaper00053292 | ||
Curator_confirmed | WBPerson712 | |||||
WBPhenotype:0000083 | Paper_evidence | WBPaper00053292 | ||||
Curator_confirmed | WBPerson712 | |||||
WBPhenotype:0000757 | Paper_evidence | WBPaper00053292 | ||||
Curator_confirmed | WBPerson712 | |||||
Transgene | WBTransgene00023641 | WBPhenotype:0002422 | Paper_evidence | WBPaper00042524 | ||
Curator_confirmed | WBPerson2987 | |||||
WBTransgene00023643 | WBPhenotype:0002422 | Paper_evidence | WBPaper00042524 | |||
Curator_confirmed | WBPerson2987 | |||||
WBTransgene00024958 | WBPhenotype:0002422 | Paper_evidence | WBPaper00048848 | |||
Curator_confirmed | WBPerson17144 | |||||
RNAi (249) | ||||||
Disease_info | Induces_disease | DOID:14330 | ||||
Disease_model_inducer | WBDOannot00000144 | |||||
Interaction (40) | ||||||
Molecule_use | inhibits protein glycosylation/secretory pathway | induces ER-stress | inhibits asparagine-linked glycosylation | a natural compound that leads to the accumulation of unfolded proteins in the ER due to its inhibitory effect on N-linked protein glycosylation | |||||
Reference | WBPaper00040397 | |||||
WBPaper00040984 | ||||||
WBPaper00005044 | ||||||
WBPaper00026830 | ||||||
WBPaper00026929 | ||||||
WBPaper00031456 | ||||||
WBPaper00032192 | ||||||
WBPaper00032255 | ||||||
WBPaper00033126 | ||||||
WBPaper00041295 |