WormBase Tree Display for Gene: WBGene00020347
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| WBGene00020347 | SMap | S_parent | Sequence | CHROMOSOME_I | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | ech-1.2 | Person_evidence | WBPerson2819 | |||||
| Sequence_name | T08B2.7 | ||||||||
| Molecular_name | T08B2.7a | ||||||||
| T08B2.7a.1 | |||||||||
| CE13431 | |||||||||
| T08B2.7b | |||||||||
| CE26950 | |||||||||
| T08B2.7b.1 | |||||||||
| T08B2.7b.2 | |||||||||
| T08B2.7b.3 | |||||||||
| Other_name | CELE_T08B2.7 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | ech-1.2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:03 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 25 Sep 2014 10:29:23 | WBPerson2970 | Name_change | CGC_name | ech-1.2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ech | ||||||||
| Allele (44) | |||||||||
| Strain | WBStrain00003519 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Contained_in_operon | CEOP1312 | ||||||||
| Ortholog (43) | |||||||||
| Paralog | WBGene00001150 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001157 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001158 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00007129 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00010035 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00019978 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00022130 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | ech-1.2 encodes one of two C. elegans enoyl-CoA hydratases/long-chain 3-hydroxyacyl-CoA dehydrogenases [EC:4.2.1.17 1.1.1.211] orthologous to human HADHA (hydroxyacyl-coenzyme A dehydrogenase/3-ketoacyl-coenzyme A thiolase/enoyl-coenzyme a hydratase (trifunctional protein), alpha subunit OMIM:600890), which when mutated leads to disease. | Curator_confirmed | WBPerson1843 | |||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 12 Nov 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable enoyl-CoA hydratase activity and long-chain-3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial fatty acid beta-oxidation multienzyme complex. Expressed in tail. Human ortholog(s) of this gene implicated in Alzheimer's disease; fatty liver disease; and mitochondrial trifunctional protein deficiency. Is an ortholog of human HADHA (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4801) | ||||
| DOID:9452 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4801) | ||||||
| DOID:0111277 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4801) | ||||||
| Molecular_info | Corresponding_CDS | T08B2.7a | |||||||
| T08B2.7b | |||||||||
| Corresponding_CDS_history | T08B2.7c:wp274 | ||||||||
| Corresponding_transcript | T08B2.7a.1 | ||||||||
| T08B2.7b.1 | |||||||||
| T08B2.7b.2 | |||||||||
| T08B2.7b.3 | |||||||||
| Other_sequence (113) | |||||||||
| Associated_feature | WBsf655275 | ||||||||
| WBsf664328 | |||||||||
| WBsf983864 | |||||||||
| WBsf219554 | |||||||||
| WBsf219555 | |||||||||
| WBsf219556 | |||||||||
| WBsf219557 | |||||||||
| WBsf219558 | |||||||||
| Experimental_info | RNAi_result (17) | ||||||||
| Expr_pattern | Expr6639 | ||||||||
| Expr1023592 | |||||||||
| Expr1038864 | |||||||||
| Expr1156447 | |||||||||
| Expr2011165 | |||||||||
| Expr2029401 | |||||||||
| Drives_construct | WBCnstr00003977 | ||||||||
| WBCnstr00025203 | |||||||||
| Construct_product | WBCnstr00025203 | ||||||||
| Microarray_results (36) | |||||||||
| Expression_cluster (124) | |||||||||
| Interaction (147) | |||||||||
| Map_info | Map | I | Position | 0.878928 | |||||
| Positive | Positive_clone | T08B2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00026800 | ||||||||
| WBPaper00031865 | |||||||||
| WBPaper00033136 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041771 | |||||||||
| WBPaper00042257 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00065140 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
