WormBase Tree Display for Gene: WBGene00019108

WBGene00019108 SMap: S_parent: Sequence: F59D6
  Identity: Version: 2
    Name: CGC_name: chpf-2 Person_evidence: WBPerson2233
      Sequence_name: F59D6.7
      Molecular_name: F59D6.7a
        F59D6.7a.1
        CE45471
        F59D6.7b
      Other_name: CELE_F59D6.7 Accession_evidence: NDB BX284605
      Public_name: chpf-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:01 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 14 Apr 2015 09:52:28 WBPerson2970 Name_change: CGC_name: chpf-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: chpf
    Allele (40)
    Strain: WBStrain00032856
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (43)
    Paralog: WBGene00003941 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00014109 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00000554 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00009260 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00020192 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable calcium ion binding activity. Predicted to be located in plasma membrane. Expressed in ray and in male. Human ortholog(s) of this gene implicated in spastic ataxia. Is an ortholog of human CHP1 (calcineurin like EF-hand protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0050952 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:17433)
  Molecular_info: Corresponding_CDS: F59D6.7a
    Corresponding_CDS_history: F59D6.7:wp220
    Corresponding_transcript: F59D6.7b
      F59D6.7a.1
    Other_sequence: EX547409.1
      PPC09890_1
      SC00980
      GR979084.1
      Tcir_isotig07859
      Acan_isotig17513
    Associated_feature: WBsf652522
      WBsf668647
      WBsf233455
  Experimental_info: RNAi_result: WBRNAi00016100 Inferred_automatically: RNAi_primary
      WBRNAi00080519 Inferred_automatically: RNAi_primary
      WBRNAi00049180 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr12598
      Expr1024518
      Expr1038248
      Expr1152926
      Expr2009998
      Expr2028239
    Drives_construct: WBCnstr00022364
      WBCnstr00026059
    Construct_product: WBCnstr00026059
    Microarray_results (16)
    Expression_cluster: WBPaper00031040:Cluster_3
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037946:MAB-5_interacting
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:excretory-cell_larva_enriched
      WBPaper00037950:excretory-cell_larva_SelectivelyEnriched
      WBPaper00037950:GABAergic-motor-neurons_larva_SelectivelyEnriched
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045140:aging_dynamic_regulation
      WBPaper00045390:ubc-9(RNAi)_downregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00046121:ecdoderm_unique
      WBPaper00046805:csr-1(RNAi)_upregulated_Set1
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048988:neuron_expressed
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050743:elli-1(sam-3)_downregulated
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_upregulated_ClassI
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053664:ins-11(tm1053)_downregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059754:C.neoformans_H99_upregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060526:plp-1(ok2155)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:microgravity_downregulated
      WBPaper00061340:Excretory_cell
      WBPaper00061340:Excretory_duct_and_pore
      WBPaper00061340:hyp7_C_lineage
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061527:R07G3.8_9125-ric-4_17408
      WBPaper00061651:Excretory_cell_enriched
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_downregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065841:71_0
      WBPaper00065841:79_1
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00032948:StarveUp1
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00036123:Atrazine_regulated
      WBPaper00037695:WC_5-day
      WBPaper00039866:ClassComp_daf-19_downregulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040821:Au-NP_regulated
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
    Interaction: WBInteraction000117439
      WBInteraction000117442
      WBInteraction000165373
      WBInteraction000209483
  Map_info: Map: V Position: -12.7957
    Positive: Positive_clone: F59D6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00035228
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene