WormBase Tree Display for Gene: WBGene00003941
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| WBGene00003941 | SMap | S_parent | Sequence | Y71H2AL | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | pbo-1 | Person_evidence | WBPerson655 | |||||
| Sequence_name | Y71H2AL.1 | ||||||||
| Molecular_name | Y71H2AL.1 | ||||||||
| Y71H2AL.1.1 | |||||||||
| CE27032 | |||||||||
| Other_name | Y71H2AL.b | Curator_confirmed | WBPerson1983 | ||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| Y71H2AL.c | Curator_confirmed | WBPerson1983 | |||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| Y71H2AL.g | Curator_confirmed | WBPerson1983 | |||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_Y71H2AL.1 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | pbo-1 | ||||||||
| DB_info | Database | WormFlux | gene | WBGene00003941 | |||||
| NDB | locus_tag | CELE_Y71H2AL.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003941|UniProtKB=Q9N2Y1 | |||||||
| family | PTHR46002 | ||||||||
| NCBI | gene | 175385 | |||||||
| RefSeq | protein | NM_065200.5 | |||||||
| TREEFAM | TREEFAM_ID | TF354284 | |||||||
| TrEMBL | UniProtAcc | Q9N2Y1 | |||||||
| UniProt_GCRP | UniProtAcc | Q9N2Y1 | |||||||
| OMIM | gene | 606988 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 06 Sep 2011 16:47:56 | WBPerson2970 | Event | Acquires_merge | WBGene00022164 | ||||
| Name_change | Sequence_name | Y71H2AL.1 | |||||||
| Acquires_merge | WBGene00022164 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pbo | ||||||||
| Allele (122) | |||||||||
| Legacy_information | [C.elegansII] sa7 : posterior body contraction during defecation very weak or absent; aBoc and Exp steps, and cycle period, normal; constipated; very slow growing. NA1. [Thomas 1990; JT] | ||||||||
| Strain | WBStrain00022771 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (32) | |||||||||
| Paralog | WBGene00014109 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00019108 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000554 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00009260 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00020192 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | pbo-1 encodes a calcium binding protein with homology to calcineurin; pbo-1 was identified in screens for mutations that disrupt the normal defecation cycle; a pbo-1 mutation results in weak or absent posterior body contractions, the first step in the defecation cycle; pbo-1 mutant animals are also slow growing and constipated. | Paper_evidence | WBPaper00001256 | |||||
| WBPaper00040129 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 14 Sep 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable calcium ion binding activity. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in spastic ataxia. Is an ortholog of human CHP1 (calcineurin like EF-hand protein 1) and CHP2 (calcineurin like EF-hand protein 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0050952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17433) | ||||
| Molecular_info | Corresponding_CDS | Y71H2AL.1 | |||||||
| Corresponding_transcript | Y71H2AL.1.1 | ||||||||
| Other_sequence (30) | |||||||||
| Associated_feature | WBsf666599 | ||||||||
| WBsf991583 | |||||||||
| WBsf991584 | |||||||||
| WBsf1014446 | |||||||||
| WBsf226290 | |||||||||
| Experimental_info | RNAi_result (30) | ||||||||
| Expr_pattern | Expr3641 | ||||||||
| Expr9662 | |||||||||
| Expr1031871 | |||||||||
| Expr1161648 | |||||||||
| Expr2014760 | |||||||||
| Expr2032994 | |||||||||
| Drives_construct | WBCnstr00014209 | ||||||||
| Construct_product | WBCnstr00011566 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (200) | |||||||||
| Interaction | WBInteraction000564123 | ||||||||
| WBInteraction000580226 | |||||||||
| WBProcess | WBbiopr:00000010 | ||||||||
| Map_info | Map | III | Position | -10.8281 | Error | 0.011837 | |||
| Positive | Positive_clone | Y71H2AL | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 1510 | |||||||
| 1669 | |||||||||
| 2304 | |||||||||
| Pos_neg_data | 6856 | ||||||||
| Reference (15) | |||||||||
| Method | Gene |
