WormBase Tree Display for Gene: WBGene00018643

WBGene00018643 SMap: S_parent: Sequence: F49F1
  Identity: Version: 2
    Name: CGC_name: drd-50 Person_evidence: WBPerson10050
      Sequence_name: F49F1.1
      Molecular_name: F49F1.1
        F49F1.1.1
        CE17084
      Other_name: CELE_F49F1.1 Accession_evidence: NDB BX284604
      Public_name: drd-50
    DB_info: Database: AceView gene 4E883
        WormQTL gene WBGene00018643
        WormFlux gene WBGene00018643
        NDB locus_tag CELE_F49F1.1
        Panther gene CAEEL|WormBase=WBGene00018643|UniProtKB=Q9GZE5
          family PTHR21724
        NCBI gene 177176
        RefSeq protein NM_068084.5
        TREEFAM TREEFAM_ID TF317956
        TrEMBL UniProtAcc Q9GZE5
        UniProt_GCRP UniProtAcc Q9GZE5
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:00 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 29 Apr 2015 12:07:40 WBPerson2970 Name_change: CGC_name: drd-50
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: drd
    Allele: WBVar01727394
      WBVar00604169
      WBVar02123921
      WBVar02124114
      WBVar01966198
      WBVar02124696
      WBVar02121201
      WBVar01668701
      WBVar02121023
      WBVar01649688
      WBVar02121770
      WBVar00902846
      WBVar02122139
      WBVar02123244
      WBVar00902847
      WBVar00902848
      WBVar00902849
      WBVar00902850
      WBVar00902851
      WBVar00902852
      WBVar00902853
      WBVar00902854
      WBVar00902855
      WBVar00902856
      WBVar00902857
      WBVar00902858
      WBVar00902859
      WBVar01999825
      WBVar02120501
      WBVar02123081
      WBVar01499790
      WBVar02121616
      WBVar02124013
      WBVar02124199
      WBVar00422705
      WBVar01499633
      WBVar00422706
      WBVar00422707
      WBVar02124587
      WBVar01630613
      WBVar02090001
      WBVar02122391
      WBVar02124792
      WBVar02122953
      WBVar02122954
      WBVar01568616
      WBVar00188457
      WBVar02152679
      WBVar02122591
      WBVar02122592
    RNASeq_FPKM (74)
    GO_annotation: 00093042
      00093043
      00093044
    Ortholog (32)
    Paralog (63)
    Structured_description: Automated_description: Involved in defense response to Gram-positive bacterium and innate immune response. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F49F1.1
    Corresponding_transcript: F49F1.1.1
    Other_sequence: NBC01774_1
      NB08687
    Associated_feature: WBsf645906
      WBsf996181
      WBsf228156
      WBsf228157
  Experimental_info: RNAi_result: WBRNAi00078259 Inferred_automatically: RNAi_primary
      WBRNAi00015337 Inferred_automatically: RNAi_primary
      WBRNAi00047876 Inferred_automatically: RNAi_primary
      WBRNAi00032555 Inferred_automatically: RNAi_primary
      WBRNAi00001965 Inferred_automatically: RNAi_primary
      WBRNAi00095432 Inferred_automatically: RNAi_primary
      WBRNAi00095424 Inferred_automatically: RNAi_primary
      WBRNAi00095411 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1022463
      Expr1151705
      Expr2011085
      Expr2029321
    Drives_construct: WBCnstr00026364
    Construct_product: WBCnstr00026364
    Microarray_results (19)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_adult_enriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040285:H2S_12hr_upregulated
      WBPaper00042194:nhr-114(RNAi)_downregulated
      WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00042561:smgl-2(RNAi)_downregulated
      WBPaper00044005:DAF-16_downregulated
      WBPaper00044030:nhr-8(hd117)_upregulated
      WBPaper00044557:DietaryRestriction_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045303:ZK1236.1(tm4178)_upregulated
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045618:fbf-1_downregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046337:monosomal_N2_vs_daf-2_upregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
      WBPaper00046496:Rifampicin_downregulated
      WBPaper00047131:daf-2(e1370)_downregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_downregulated_N2-background
      WBPaper00048988:neuron_expressed
      WBPaper00049018:ham-3(RNAi)_downregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049368:daf-2(e1370)_downregulated
      WBPaper00049377:MWCNT_upregulated
      WBPaper00049484:elt-2(RNAi)_downregulated_L4
      WBPaper00049498:npr-1(ur89)_regulated_5
      WBPaper00049635:dop-1(vs100)_upregulated
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049920:hyl-2(tm2031)_upregulated
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050121:mir-60(n4947)_downregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050193:cec-4(ok3124)_upregulated_L1
      WBPaper00050234:lin-28(RNAi)_downregulated
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_adult_25C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:body-muscle_enriched
      WBPaper00050990:body-muscle_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051137:Orsay-virus_upregulated_rde-1(ne219)
      WBPaper00051388:Glucose-diet_downregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053318:Aging_upregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_upregulated_mRNA
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053402:his-3(RNAi)_upregulated
      WBPaper00053771:up_at_24h-NaCl
      WBPaper00053771:up_at_dpy-7(e88)
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:25C_upregulated_OP50
      WBPaper00053814:25C_upregulated_PY79
      WBPaper00053888:drh-3(rrr2)_upregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00054872:egl-9(sa307)_upregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_downregulated
      WBPaper00055827:daf-2(e1370)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055944:C.butyricum_vs_OP50_downregulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056073:NHR-86_interacting_promoter
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:gut-microbiota_upregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056218:daf-16(mu86)_downregulated_Day7
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_atf-7(qd22qd130)_dependent
      WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00056868:P.aeruginosa_upregulated_smallRNA
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
      WBPaper00057196:raga-1(ok386)_upregulated)
      WBPaper00057347:nhr-14(tm1473)_upreglated
      WBPaper00058665:amino-functionized-graphene-oxide_upregulated_mRNA
      WBPaper00058665:graphene-oxide_upregulated_mRNA
      WBPaper00058948:npr-8(ok1439)_downregulated_PA14
      WBPaper00058948:PA14_downregulated
      WBPaper00058955:heatshock_upregulated_CE
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059191:hsp-16.2p-LIN-29_downregulated
      WBPaper00059253:sucrose_downregulated
      WBPaper00059253:sucrose_stearic-acid_downregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_upregulated
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059421:daf-3(mgDf90)_upregulated
      WBPaper00059426:Ag-nanoparticles_upregulated
      WBPaper00059426:SiO2-nanoparticles_downregulated
      WBPaper00059477:lin-32(RNAi)_regulated
      WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_downregulated_N2
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059735:glucose_downregulated_N2
      WBPaper00059754:P.aeruginosa_PA14_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060273:isp-1(qm150)_downregulated
      WBPaper00060273:vrk-1(RNAi)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060764:swsn-1(os22ts)_upregulated
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061081:skpo-1(ok1640)_upregulated_OG1RF
      WBPaper00061319:pnp-1(jy90)_upregulated
      WBPaper00061319:pnp-1(jy121)_upregulated
      WBPaper00061340:Arcade_cell_anterior_and_posterior
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061390:daf-22(ok693)_ascarosides_downregulated
      WBPaper00061478:pie-1(ne4433)_upregulated
      WBPaper00061527:C17H12.6-swt-6
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061590:CGP37157_upregulated
      WBPaper00061636:atracurium_downregulated
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00061952:daf-18(nr2037)_upregulated
      WBPaper00062078:NMR-HspB1_regulated
      WBPaper00062146:MOG-7-degron_2h_regulated
      WBPaper00062156:jmjd-1.2(zr1010)_downregulated
      WBPaper00062156:jmjd-5(zr1234)_updownregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:daf-16(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062440:crh-1(n3315)_upregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062590:Aging_upregulated_intestine
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064382:auxin_upregulated
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064632:daf-2(e1370)_downregulated_intestine
      WBPaper00064721:fasn-1(g14)_downregulated_starved
      WBPaper00064727:daf-2(e1370)_downregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00064871:hypoxia_upregulated_F3
      WBPaper00065005:sams-3(RNAi)_upregulated
      WBPaper00065005:sams-4(RNAi)_upregulated
      WBPaper00065029:cadmium_upregulated
      WBPaper00065086:N2_N.parisii_regulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065158:25C_vs_15C_upregulated_AFD
      WBPaper00065158:25C_vs_15C_upregulated_WholeAnimal
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065823:pmk-1(km25)_downregulated
      WBPaper00065835:Day5_vs_Day1_upregulated
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:mml-1(RNAi)-neuron_upregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      cgc4489_group_11
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00028482:PA14_upregulated
      WBPaper00029437:rde-4_upregulated
      WBPaper00031060:2-deoxy-D-glucose_upregulated
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032062:age_regulated_genes
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_D
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00037147:heatshock_downregulated
      WBPaper00037704:ABZ_up_regulated
      WBPaper00038462:aging_downregulated
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041211:RPW-24_Up
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00042128:gei-8(ok1671)_upregulated
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00044091:Bpseudomallei_induced_12h
      WBPaper00045401:N.parisii_34h_upregulated_N2
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc5976]:class_2
    Interaction: WBInteraction000236426
      WBInteraction000292066
      WBInteraction000317892
      WBInteraction000402983
      WBInteraction000455812
      WBInteraction000457799
  Map_info: Map: IV Position: -0.675337
    Positive: Positive_clone: F49F1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027722
    WBPaper00028482
    WBPaper00032370
    WBPaper00044557
    WBPaper00058665
    WBPaper00062322
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene