WormBase Tree Display for Gene: WBGene00018353

WBGene00018353 SMap: S_parent: Sequence: F42G2
  Identity: Version: 2
    Name: CGC_name: fbxa-182 Person_evidence: WBPerson655
      Sequence_name: F42G2.4
      Molecular_name: F42G2.4
        F42G2.4.1
        CE53955
      Other_name: CELE_F42G2.4 Accession_evidence: NDB BX284602
      Public_name: fbxa-182
    DB_info: Database: WormQTL gene WBGene00018353
        WormFlux gene WBGene00018353
        NDB locus_tag CELE_F42G2.4
        NCBI gene 173594
        RefSeq protein NM_001377723.1
        TREEFAM TREEFAM_ID TF322500
        TrEMBL UniProtAcc Q6HAE7
        UniProt_GCRP UniProtAcc Q6HAE7
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:00 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 01 Mar 2007 11:55:19 WBPerson2970 Name_change: CGC_name: fbxa-182
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fbxa
    Allele (159)
    Strain: WBStrain00047576
    RNASeq_FPKM (74)
    Ortholog (29)
    Paralog (219)
    Structured_description: Concise_description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction. Paper_evidence: WBPaper00012854
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enriched in RICL; RICR; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including 1-methylnicotinamide; methylmercuric chloride; and D-glucopyranose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and F-box A protein FB224. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F42G2.4
    Corresponding_CDS_history: F42G2.4:wp274
      F42G2.4a:wp125
      F42G2.4a:wp151
      F42G2.4b:wp125
      F42G2.4b:wp151
    Corresponding_transcript: F42G2.4.1
    Associated_feature: WBsf665396
      WBsf222764
  Experimental_info: RNAi_result: WBRNAi00014834 Inferred_automatically: RNAi_primary
      WBRNAi00047113 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1021429
      Expr1150980
      Expr2011502
      Expr2029739
    Drives_construct: WBCnstr00026587
    Construct_product: WBCnstr00026587
    Microarray_results (15)
    Expression_cluster: WBPaper00031040:Cluster_5
      WBPaper00032425:up_in_lin-35
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:intestine_CoreEnriched
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_larva_enriched
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038168:lin-35_upregulated
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00040560:hpl-2_L3_upregulated
      WBPaper00042194:nhr-114(RNAi)_downregulated
      WBPaper00042477:prp-8(RNAi)_upregulated_RNAseq
      WBPaper00042477:rsr-2(RNAi)_upregulated_RNAseq
      WBPaper00044037:eat-2_upregulated
      WBPaper00044260:nicotic-acid_downregulated
      WBPaper00044316:CH3HgCl_2.0uM_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045257:bar-1(ga80)_upregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045401:N.parisii_8h_upregulated
      WBPaper00045401:N.parisii_30h_upregulated
      WBPaper00045401:N.parisii_64h_upregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00046509:lin-35(n745)_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048952:glucose_repressed
      WBPaper00048988:neuron_expressed
      WBPaper00049098:heat-induced_hrde-1(tm1200)
      WBPaper00049098:heat-induced_N2
      WBPaper00049484:elt-2(RNAi)_upregulated_L4
      WBPaper00049498:npr-1(ur89)_regulated_2
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00049954:BPA_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051137:N.parisii-virus_upregulated_N2
      WBPaper00051137:Orsay-virus_upregulated_N2
      WBPaper00051137:Orsay-virus_upregulated_rde-1(ne219)
      WBPaper00051371:Orsay-virus-infection_upregulated_rde-1(ne219)
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:OrsayVirus-infection_upregulated
      WBPaper00053020:OrsayVirus-infection_upregulated_microarray
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00053814:25C_upregulated_OP50
      WBPaper00053888:drh-3(rrr2)_upregulated
      WBPaper00053909:N2_vs_CB4856_downregulated
      WBPaper00054410:set-9(rw5)_upregulated
      WBPaper00054410:set-26(tm2467)_upregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:atfs-1(gk3094)_upregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056073:R24_upregulated_nhr-86_dependent
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_adult
      WBPaper00056169:rrf-3(pk1426)_upregulated_L4
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:flcn-1(ok975)_upregulated
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00058665:graphene-oxide_upregulated_mRNA
      WBPaper00058711:paraquat_downregulated
      WBPaper00058711:wdr-5(ok1417)_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059191:hsp-16.2p-LIN-29_downregulated
      WBPaper00059253:stearic-acid_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059373:stt-3(RNAi)_upregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059739:hira-1(gk835598)_upregulated_L4
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00060084:cco-1(RNAi)_upregulated_N2
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:CoCl2_6hr_upregulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060871:M.humicola-extract_4h_regulated
      WBPaper00060909:atfs-1(et18)_upregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061319:pnp-1(jy90)_upregulated
      WBPaper00061319:pnp-1(jy121)_upregulated
      WBPaper00061340:RIC
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061527:C17H1.6-C17H1.13
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061952:daf-18(nr2037)_downregulated
      WBPaper00061952:daf-18(yh1)_downregulated
      WBPaper00062056:lin-15B(n744)_upregulated
      WBPaper00062056:lin-15B(we23)_upregulated
      WBPaper00062056:lin-35(n745)_upregulated
      WBPaper00062056:lin-37(n758)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062184:PA14_upregulated
      WBPaper00062193:daf-16(RNAi)_downregulated
      WBPaper00062305:P.brevicompactum_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062345:bortezomib_30min_upregulated_N2
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062587:lsl-1(ljm1)_downregulated
      WBPaper00062587:lsl-1(tm4769)_downregulated
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064532:pals-22(jy3)_upregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064871:hypoxia_upregulated_F2
      WBPaper00065029:cadmium_upregulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:JU1400_N.ironsii_regulated
      WBPaper00065086:JU1400_N.parisii_regulated
      WBPaper00065086:N2_N.ausubeli_regulated
      WBPaper00065086:N2_N.ferruginous_regulated
      WBPaper00065086:N2_N.ironsii_regulated
      WBPaper00065086:N2_N.parisii_regulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day1_20C
      WBPaper00065288:mdt-15(tm2182)_upregulated
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065835:Day5_vs_Day1_upregulated
      WBPaper00065841:120_0
      WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00065995:M.humicola-extract_downregulated_N2
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4489_group_21
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026980:intestine_enriched
      WBPaper00029437:rde-4_upregulated
      WBPaper00031850:mdt-15(RNAi)_upregulated
      WBPaper00032062:age_regulated_genes
      WBPaper00035227:heat_shock_regulated
      WBPaper00037695:LD_3-day
      WBPaper00037695:WC_5-day
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045401:N.parisii_34h_upregulated_N2
      WBPaper00045673:colistin_upregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00050515:nipi-3(fr4)_upregulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
    Interaction (27)
  Map_info: Map: II Position: -13.8292 Error: 0.00069
    Positive: Positive_clone: F42G2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00012854
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene