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WormBase Tree Display for Gene: WBGene00017578

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Name Class

WBGene00017578SMapS_parentSequenceCHROMOSOME_IV
IdentityVersion2
NameCGC_namedrl-1Paper_evidenceWBPaper00045036
Sequence_nameF18F11.5
Molecular_nameF18F11.5
F18F11.5.1
CE48587
Other_namemekk-3Paper_evidenceWBPaper00045036
CELE_F18F11.5Accession_evidenceNDBBX284604
Public_namedrl-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:59WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
230 May 2014 11:12:36WBPerson2970Name_changeCGC_namedrl-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdrl
Allele (96)
Possibly_affected_byWBVar02153185
WBVar02159007
StrainWBStrain00055667
WBStrain00055641
RNASeq_FPKM (74)
GO_annotation00083355
00083356
00122927
00122928
00122929
Ortholog (18)
Paralog (19)
Structured_descriptionConcise_descriptiondrl-1 encodes a protein kinase similar to the mammalian MEKK3-like kinase; DRL-1 functions in C. elegans to regulate dietary restriction-mediated longevity.Paper_evidenceWBPaper00045036
Curator_confirmedWBPerson1843
Date_last_updated05 Aug 2014 00:00:00
Automated_descriptionPredicted to enable ATP binding activity and protein kinase activity. Predicted to be located in membrane. Expressed in body wall musculature; neurons; seam cell; and vulval muscle.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF18F11.5
Corresponding_transcriptF18F11.5.1
Other_sequenceAcan_isotig15406
FK804347.1
CBC00121_1
Associated_featureWBsf995121
WBsf995122
WBsf1016535
WBsf1016536
WBsf227829
WBsf227830
Experimental_infoRNAi_result (26)
Expr_patternExpr11696
Expr16267
Expr16268
Expr1019421
Expr1037549
Expr1148935
Expr2011090
Expr2029326
Drives_constructWBCnstr00019316
WBCnstr00027192
WBCnstr00042868
Construct_productWBCnstr00027192
WBCnstr00042868
Microarray_results (16)
Expression_clusterWBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:CEP-sheath-cells_adult_enriched
WBPaper00037950:hypodermis_larva_enriched
WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
WBPaper00042561:smg-2(RNAi)_upregulated
WBPaper00044578:reduced-humidity_downregulated_microarray
WBPaper00044736:flat_dev_expression
WBPaper00045521:Gender_Neutral
WBPaper00045861:set-2(ok952)_upregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00047131:daf-2(e1370)_upregulated_N2-background
WBPaper00048690:gonad-male-biased
WBPaper00048690:male-Z1-Z4-daughter_enriched
WBPaper00048988:neuron_expressed
WBPaper00049484:elt-2(RNAi)_downregulated_L4
WBPaper00049545:cco-1(RNAi)_upregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
WBPaper00049942:HeatShock_downregulated_hsf-1(+)
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:intestine_enriched
WBPaper00050990:intestine_expressed
WBPaper00051039:intestine_enriched
WBPaper00051404:alg-2(ok304)_downregulated
WBPaper00053094:adr-2(ok735)_neuron_downregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
WBPaper00053606:N2_vs_elt-2(ca15)_downregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055060:flr-1(RNAi)_upregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00055897:heat-shock_downregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056826:hmc_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057068:ints-4(RNAi)_downregulated
WBPaper00057288:Cold_downregulated_transcript
WBPaper00058691:cfp-1(tm6369)_upregulated
WBPaper00058691:sin-3(tm1276)_upregulated
WBPaper00058948:PA14_downregulated
WBPaper00059191:hsp-16.2p-LIN-29_downregulated
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059895:wounding_downregulated
WBPaper00059987:Wounding_downregulated
WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr
WBPaper00060661:sensory-neuron_depleted
WBPaper00061203:spr-1(ok2144)_downregulated
WBPaper00061340:g1A
WBPaper00061340:hyp3
WBPaper00061439:unc-30(ok613)_downregulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:hsf-1(RNAi)_downregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062345:bortezomib_4h_downregulated_N2
WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064716:paraquat_downregulated
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
cgc4489_group_25
WBPaper00025099:MA_specific
WBPaper00025099:NI_specific
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026952:class_B
WBPaper00026980:intestine_enriched
WBPaper00028948:cep-1(gk138)+UV_upregulated
WBPaper00032062:age_regulated_genes
WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
WBPaper00041174:environmental
WBPaper00041174:genotypic
WBPaper00041174:genotypic_and_environmental
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00055899:nitroguanidine_regulated
[cgc6390]:Cluster_B
[cgc6390]:Cluster_C
[cgc6390]:herm_soma-enriched
InteractionWBInteraction000542596
WBInteraction000542627
WBInteraction000543104
WBInteraction000543105
WBInteraction000543113
Map_infoMapIVPosition-26.493
PositivePositive_cloneF18F11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (14)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene