WormBase Tree Display for Gene: WBGene00016877

WBGene00016877 SMap: S_parent: Sequence: C52D10
  Identity: Version: 2
    Name: Sequence_name: C52D10.3
      Molecular_name: C52D10.3a
        C52D10.3a.1
        CE50642
        C52D10.3b
        CE50635
        C52D10.3b.1
      Other_name: CELE_C52D10.3 Accession_evidence: NDB BX284604
      Public_name: C52D10.3
    DB_info: Database: AceView gene 4S131
        WormQTL gene WBGene00016877
        WormFlux gene WBGene00016877
        NDB locus_tag CELE_C52D10.3
        Panther gene CAEEL|EnsemblGenome=WBGene00016877|UniProtKB=A0A0K3AXD0
          family PTHR31005
        NCBI gene 3565402
        RefSeq protein NM_001313023.2
            NM_001313022.2
        TrEMBL UniProtAcc A0A0K3AXD0
            A0A0K3AV18
        UniProt_GCRP UniProtAcc A0A0K3AXD0
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 09 Mar 2015 14:30:37 WBPerson4025 Event: Acquires_merge: WBGene00016875
      Acquires_merge: WBGene00016875
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (210)
    RNASeq_FPKM (74)
    Ortholog (29)
    Paralog (4)
    Structured_description: Automated_description: Enriched in NSM; intestine; and pharyngeal muscle cell based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-five chemicals including methylmercuric chloride; rotenone; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4139; N-terminal domain of unknown function (DUF4140); Domain of unknown function (DUF4139); Domain of unknown function DUF4140; and Conserved hypothetical protein CHP02231. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C52D10.3a
      C52D10.3b
    Corresponding_CDS_history: C52D10.3:wp114
      C52D10.3:wp158
      C52D10.3:wp247
    Corresponding_transcript: C52D10.3a.1
      C52D10.3b.1
    Other_sequence (11)
    Associated_feature (11)
  Experimental_info: RNAi_result (11)
    Expr_pattern: Expr1018708
      Expr1025594
      Expr1037240
      Expr1037241
      Expr1146984
      Expr1146988
      Expr2001862
      Expr2020088
    Drives_construct: WBCnstr00027733
    Construct_product: WBCnstr00027733
    Microarray_results (43)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032425:up_in_alg-1
      WBPaper00032425:up_in_lin-35
      WBPaper00032425:up_in_rde-4
      WBPaper00032425:up_in_zfp-1
      WBPaper00032528:L3_enriched
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_embryo_SelectivelyEnriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_embryo_enriched
      WBPaper00037950:pharyngeal-muscle_embryo_SelectivelyEnriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_downregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040560:hpl-2_L3_upregulated
      WBPaper00040990:PA14_downregulated
      WBPaper00042477:rsr-2(RNAi)_downregulated_RNAseq
      WBPaper00044037:eat-2_downregulated
      WBPaper00044246:pgrn-1_ced-3_ced-1_downregulated
      WBPaper00044316:CH3HgCl_2.0uM_downregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044426:rotenone_5day_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044656:tatn-1(qd182)_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044760:somatic_specific
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045729:gld-2(RNAi)_upregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00045974:NSM_enriched_totalRNA_tiling
      WBPaper00046121:endoderm_unique
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00047132:skn-1(RNAi)_downregulated
      WBPaper00049018:ham-3(RNAi)_upregulated
      WBPaper00049134:hpk-1(pk1393)_downregulated
      WBPaper00049217:DAF-16_upregulated
      WBPaper00049484:elt-2(RNAi)_downregulated_L4
      WBPaper00049495:starvation-refeeding_regulated
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049498:npr-1(ur89)_regulated_8
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00049954:BPA_downregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050096:P.aeruginosa_downregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050193:cec-4(ok3124)_downregulated_L1
      WBPaper00050193:met-2(n4256)set-25(n5021)_downregulated_L1
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050504:hrp-2(RNAi)_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050928:male-mating_downregulated
      WBPaper00051039:intestine_enriched
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_specific
      WBPaper00051257:Levamisole_downregulated
      WBPaper00051265:F4_morc-1(tm6048)_downregulated
      WBPaper00051305:vit-2(ac3)_downregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053154:human-amyloid-beta_tau_regulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(ot267)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053318:Aging_upregulated_mRNA_N2
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053771:up_at_3h-NaCl
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00054758:alg-1(gk204)_downregulated
      WBPaper00054872:egl-9(sa307)_downregulated
      WBPaper00055013:spt-16(RNAi)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055897:heat-shock_upregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056039:efa-6(tm3124)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056169:rrf-3(pk1426)_downregulated_L4
      WBPaper00056284:ints-4(RNAi)_downregulated
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056290:mdt-15(mg584)_upregulated
      WBPaper00056330:glycine_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057068:Cadmium_downregulated
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00057265:metaformin_downregulated_OP50
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058711:paraquat_upregulated
      WBPaper00058711:skn-1(lax188)_downregulated
      WBPaper00058711:wdr-5(ok1417)_upregulated
      WBPaper00058948:PA14_upregulated
      WBPaper00058958:100mGy-irradiation-72h_upregulated
      WBPaper00059117:B.subtilis_downregulated
      WBPaper00059175:hlh-17p-XBP-1_downregulated
      WBPaper00059231:alh-6(lax105)_L4_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059373:stt-3(RNAi)_downregulated
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059739:hira-1(gk835598)_downregulated_adult
      WBPaper00059739:hira-1(gk835598)_downregulated_L1
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060434:pH4.33_vs_pH6.33_downrgulated
      WBPaper00060445:ikb-1(nr2027)_downregulated_L4
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061106:endu-2(tm4977)_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061340:Intestine
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:gst-26-pho-1_10767
      WBPaper00061527:sre-33-ZK1025.1_8337
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00061952:daf-18(nr2037)_downregulated
      WBPaper00061995:mter-4(syb3662syb3403)_upregulated
      WBPaper00062118:neural-HSF-1_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062167:mbl-1(tm1563)_downregulated
      WBPaper00062184:PA14_downregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062354:H.zoospora_12h_regulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062684:pathogen_downregulated_N2
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064156:lipl-4(overexpress)_downregulated
      WBPaper00064473:ets-4(rrr16)_upregulated
      WBPaper00064532:pals-25(icb98)_downregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00064871:hypoxia_upregulated_F3
      WBPaper00064871:PA14_downregulated_AWA
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065005:sams-3(RNAi)_upregulated
      WBPaper00065005:sams-4(RNAi)_upregulated
      WBPaper00065074:glna(-)_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065225:nhr-42(tm1375)_downregulated_S.aureus-infected
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065272:dhgd-1(tm6671)_downregulated
      WBPaper00065315:mating_downregulated_Day2-7
      WBPaper00065315:mating_downregulated_Day6-7
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065392:Lb.delbrueckii_upregulated
      WBPaper00065392:P.pentosaceus_upregulated
      WBPaper00065581:hpk-1(pk1393)_downregulated
      WBPaper00065734:unc-25(e156)_downregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065746:tmc-1(rg1003)_upregulated
      WBPaper00065835:Day5_vs_Day1_upregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065835:mtH2S-AP39-L1-treatment_upregulated_Day11
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_transcript
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00065995:M.humicola-extract_upregulated_N2
      WBPaper00066110:Doxorubicin_downregulated_diploid
      WBPaper00066118:cyclobutrifluram_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_1_4
      cgc4489_group_8
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00028789:PA14_vs_gacA_downregulated_8hr
      WBPaper00028789:PA14_vs_OP50_downregulated_4hr
      WBPaper00028789:PA14_vs_OP50_downregulated_8hr
      WBPaper00029437:dcr-1_upregulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00031662:spaceflight_upregulated
      WBPaper00032948:FedUp
      WBPaper00034739:N2lessDR1350
      WBPaper00035479:daf-16(RNAi)_downregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00036286:Pattern_C
      WBPaper00036383:ash-2_Day8_regulated
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00037695:WC_5-day
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00038304:octr-1_regulated
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00038462:aging_downregulated
      WBPaper00040116:pRJ-FR.5_down_regulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040963:TA200_down
      WBPaper00040963:TA300_down
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
      WBPaper00042236:flcn-1(ok975)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045401:N.parisii_34h_upregulated_N2
      WBPaper00046083:oga-1(ok1207)_OP50_downregulated
      WBPaper00046083:ogt-1(ok1474)_OP50_downregulated
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00046548:dafachronic-acid_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053827:pyoverdine_upregulated
      WBPaper00055899:2,4-Dinitroanisole_regulated
      WBPaper00055899:nitroguanidine_regulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc5976]:class_1
      [cgc6390]:Cluster_B
      [cgc6390]:Cluster_C
      [cgc6390]:male_sex-enriched
    Interaction: WBInteraction000152898
      WBInteraction000338202
      WBInteraction000379116
      WBInteraction000415683
      WBInteraction000503115
      WBInteraction000504125
      WBInteraction000543569
  Map_info: Positive: Positive_clone: C52D10 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: IV 16.2407
  Method: Gene