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WormBase Tree Display for Gene: WBGene00015479

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Name Class

WBGene00015479SMapS_parentSequenceC05D10
IdentityVersion2
NameCGC_namewht-1Person_evidenceWBPerson253
Sequence_nameC05D10.3
Molecular_nameC05D10.3a
C05D10.3a.1
CE52537
C05D10.3b
CE52612
C05D10.3b.1
Other_nameCELE_C05D10.3Accession_evidenceNDBBX284603
Public_namewht-1
DB_infoDatabaseAceViewgene3H174
WormQTLgeneWBGene00015479
WormFluxgeneWBGene00015479
NDBlocus_tagCELE_C05D10.3
PanthergeneCAEEL|WormBase=WBGene00015479|UniProtKB=Q11180
familyPTHR48041
NCBIgene175859
RefSeqproteinNM_001361720.3
NM_001361719.2
SwissProtUniProtAccQ11180
UniProt_GCRPUniProtAccQ11180
OMIMgene603756
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
204 Jun 2007 15:54:19WBPerson2970Name_changeCGC_namewht-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classwht
Allele (36)
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (47)
ParalogWBGene00006522Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00007060Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00007513Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00007631Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00008950Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00012925Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00017179Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00021535Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00016973Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionC05D10.3 encodes an ATP-binding cassette (ABC) transporter; C05D10.3 activity is required for efficient RNA interference (RNAi) of a germline-expressed target, pop-1.Paper_evidenceWBPaper00027644
Curator_confirmedWBPerson1843
Date_last_updated09 Mar 2007 00:00:00
Automated_descriptionPredicted to enable ATPase-coupled transmembrane transporter activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including gout; hematologic cancer (multiple); and toxic encephalopathy. Is an ortholog of human ABCG2 (ATP binding cassette subfamily G member 2 (JR blood group)).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:8552Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:74)
DOID:3602Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:74)
DOID:3459Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:74)
DOID:707Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:74)
DOID:4450Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:74)
DOID:9952Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:74)
DOID:8761Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:74)
DOID:13189Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:74)
DOID:9538Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:74)
DOID:9119Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:74)
Molecular_infoCorresponding_CDSC05D10.3a
C05D10.3b
Corresponding_CDS_historyC05D10.3:wp263
Corresponding_transcriptC05D10.3a.1
C05D10.3b.1
Other_sequenceJO472040.1
BUC01992_1
JI168809.1
MAC00309_1
HC08928
HCC12092_1
MA00856
CBC06624_1
Associated_featureWBsf666955
WBsf717914
WBsf992631
WBsf226758
WBsf226759
WBsf226760
Experimental_infoRNAi_resultWBRNAi00010194Inferred_automaticallyRNAi_primary
WBRNAi00039722Inferred_automaticallyRNAi_primary
WBRNAi00005372Inferred_automaticallyRNAi_primary
WBRNAi00028489Inferred_automaticallyRNAi_primary
Expr_patternChronogram2001
Expr5165
Expr1015874
Expr1036619
Expr1143819
Expr2018062
Expr2036199
Drives_constructWBCnstr00002025
WBCnstr00028814
Construct_productWBCnstr00028814
Microarray_results (21)
Expression_cluster (167)
InteractionWBInteraction000114198
WBInteraction000114199
WBInteraction000114200
WBInteraction000114201
WBInteraction000123461
WBInteraction000235719
WBInteraction000333604
Map_infoMapIIIPosition-1.42088Error0.0006
PositivePositive_cloneC05D10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027155
WBPaper00027644
WBPaper00031484
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene