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WormBase Tree Display for Gene: WBGene00015332

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Name Class

WBGene00015332SMapS_parentSequenceC02C2
IdentityVersion2
NameCGC_nametyr-1Person_evidenceWBPerson69
Sequence_nameC02C2.1
Molecular_nameC02C2.1
C02C2.1.1
CE06754
Other_nameCELE_C02C2.1Accession_evidenceNDBBX284603
Public_nametyr-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:55WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
211 Feb 2005 11:34:52WBPerson2970Name_changeCGC_nametyr-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtyr
Allele (34)
StrainWBStrain00032008
RNASeq_FPKM (74)
GO_annotation00041196
00041197
00041198
00041199
00121250
Ortholog (44)
ParalogWBGene00009001Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00010060Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00010661Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00021553Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00016419Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00022231Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00017483Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionC02C2.1 encodes a tyrosinase homolog with a glutamine/asparagine-rich domain.Paper_evidenceWBPaper00005068
WBPaper00012788
WBPaper00012830
WBPaper00012882
WBPaper00012897
WBPaper00013003
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable metal ion binding activity and monooxygenase activity. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human DCT (dopachrome tautomerase) and TYR (tyrosinase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050633Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:8465Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:0070097Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12450)
DOID:8923Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:0050632Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442,HGNC:12450,HGNC:2709)
DOID:12306Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:0070095Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:0070094Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:1909Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:10123Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442,HGNC:12450)
Molecular_infoCorresponding_CDSC02C2.1
Corresponding_transcriptC02C2.1.1
Other_sequence (31)
Associated_featureWBsf993180
WBsf993181
WBsf993182
WBsf993183
WBsf1015330
WBsf225291
WBsf225292
WBsf225293
WBsf225294
Experimental_infoRNAi_resultWBRNAi00098213Inferred_automaticallyRNAi_primary
WBRNAi00039406Inferred_automaticallyRNAi_primary
WBRNAi00028334Inferred_automaticallyRNAi_primary
WBRNAi00098217Inferred_automaticallyRNAi_primary
WBRNAi00005452Inferred_automaticallyRNAi_primary
WBRNAi00007421Inferred_automaticallyRNAi_primary
WBRNAi00009978Inferred_automaticallyRNAi_primary
WBRNAi00039403Inferred_automaticallyRNAi_primary
WBRNAi00005197Inferred_automaticallyRNAi_primary
Expr_patternExpr1020752
Expr1143519
Expr2017685
Expr2035823
Drives_constructWBCnstr00028927
Construct_productWBCnstr00028927
Microarray_results (19)
Expression_clusterWBPaper00031040:Cluster_3
WBPaper00031040:TGF-beta_adult_upregulated
WBPaper00032031:DConiospora_upregulated_cDNA_24h
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00040560:hpl-2_L3_downregulated
WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray
WBPaper00044736:oscillating_dev_expression
WBPaper00045017:blmp-1(tm548)_upregulated
WBPaper00045314:S.aureus-induced_hlh-30(tm1978)
WBPaper00045314:S.aureus-induced_N2
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Gender_Neutral
WBPaper00045774:clk-1_upregulated
WBPaper00045934:wrn-1(gk99)_upregulated
WBPaper00046012:tdp-1(ok803)_upregulated
WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00046858:elt-2(RNAi)_downregulated
WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
WBPaper00047131:daf-2(e1370)_upregulated_N2-background
WBPaper00048988:daf-2(e1370)_upregulated_neuron
WBPaper00048988:neuron_expressed
WBPaper00049545:cco-1(RNAi)_upregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
WBPaper00049626:UNC-75_target
WBPaper00049732:blmp-1(tm548);daf-7(e1372ts)_vs_daf-7(e1372ts)_downregulated
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050080:rbr-2(tm3141)_downregulated
WBPaper00050094:mes-6(bn66)_upregulated
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050412:cco-1(RNAi)_upregulated_N2
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050743:elli-1(sam-3)_downregulated
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
WBPaper00050990:hypodermis_enriched
WBPaper00050990:hypodermis_expressed
WBPaper00051265:F4_hrde-1(tm1200)_upregulated
WBPaper00051404:alg-1(gk214)_upregulated
WBPaper00051404:alg-2(ok304)_upregulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00053402:cco-1(RNAi)_upregulated
WBPaper00053402:his-3(RNAi)_upregulated
WBPaper00053664:ins-11(tm1053)_upregulated
WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
WBPaper00053810:clk-1(qm30)_upregulated
WBPaper00053810:daf-2(e1370)_upregulated
WBPaper00053810:isp-1(qm150)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00053810:sod-2(ok1030)_upregulated
WBPaper00053814:15C_downregulated_PY79
WBPaper00054191:H3.3(null)_embryo_upregulated
WBPaper00054493:hpl-2(tm1489)_downregulated
WBPaper00055013:hmg-3(bar24)_upregulated
WBPaper00055013:hmg-4(RNAi)_upregulated
WBPaper00055013:spt-16(RNAi)_upregulated
WBPaper00055060:flr-1(RNAi)_downregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Psora_downregulated
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rapamycin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin-Psora_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
WBPaper00055941:nuo-6(qm200)_upregulated
WBPaper00055971:nhl-2(ok818)_20C_upregulated
WBPaper00056161:male_enriched_siRNA
WBPaper00056275:P.aeruginosa_upregulated
WBPaper00056275:P.aeruginosa_upregulated_atf-7(qd22qd130)_dependent
WBPaper00056443:DietaryRestriction_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056617:adr-1_upregulated_embryo_transcript
WBPaper00056826:SGP_biased
WBPaper00056868:P.aeruginosa_upregulated_smallRNA
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057068:ints-4(RNAi)_upregulated
WBPaper00057068:numr-1(RNAi)_downregulated
WBPaper00057068:numr-1(RNAi)_downregulated_Cadmium
WBPaper00057154:HeatShock_downregulated_mRNA
WBPaper00057154:HeatShock_upregulated_miRNA-target
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00058969:RIS_depleted
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059537:ngn-1(ok2200)_upregulated
WBPaper00059566:wdr-23(mac32)_upregulated
WBPaper00059739:hira-1(gk835598)_upregulated_adult
WBPaper00059739:hira-1(gk835598)_upregulated_L4
WBPaper00059987:Wounding_upregulated
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060100:SiNP_downregulated_mRNA
WBPaper00060273:isp-1(qm150)_upregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00060703:nas-38(ok3407)_upregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061274:microgravity_downregulated
WBPaper00061340:AIB
WBPaper00061340:OLQ_grandparent
WBPaper00061340:OLQ_parent
WBPaper00061340:SIB
WBPaper00061341:28C_24h_upregulated
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061527:col-128-cdh-10_9234
WBPaper00061530:nhr-49(e2144)_upregulated
WBPaper00061823:mex-3(spr9)_downregulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064539:nhr-114(gk849)_upregulated
WBPaper00064716:paraquat_downregulated
WBPaper00064727:daf-2(e1370)_upregulated
WBPaper00065096:25C_vs_20C_upregulated
WBPaper00065096:npr-8(ok1439)_upregulated_Day1_20C
WBPaper00065158:AFD_depleted
WBPaper00065835:Day5_vs_Day1_downregulated
WBPaper00065835:Day11_vs_Day1_downregulated
WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
WBPaper00065841:0_0
WBPaper00065841:33_0
WBPaper00065841:33_1
WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066062:xrep-4(lax137)_upregulated
cgc4489_group_5
WBPaper00025141:N2_Expressed_Genes
WBPaper00028948:cep-1(gk138)_upregulated
WBPaper00034739:N2lessDR1350
WBPaper00035084:embryo_enriched_AIN-2_IP
WBPaper00035873:dpy-10_regulated
WBPaper00035873:osm-7_regulated
WBPaper00036286:Pattern_I
WBPaper00038172:crh-1null_up_regulated
WBPaper00038172:tax-6null_up_regulated
WBPaper00038462:aging_downregulated
WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
WBPaper00040210:Chlorpyrifos_24C_regulated
WBPaper00040963:Q200_up
WBPaper00041002:HQ_3d_2.0mM_Up
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00042274:tbx-2(bx59)_upregulated
WBPaper00044091:Bpseudomallei_induced_8h
WBPaper00044091:Bpseudomallei_induced_12h
WBPaper00045015:acs-3(ft5)_upregulated
WBPaper00045015:nhr-25(RNAi)_upregulated
WBPaper00047070:N2_UV_upregulated
WBPaper00047070:xpa-1_UV_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
WBPaper00048989:N2_rapamycin_upregulated
WBPaper00055899:nitroguanidine_regulated
WBPaper00057098:SiO2-nanoparticles_downregulated
Interaction (17)
Map_infoMapIIIPosition-0.517852Error0.006315
PositivePositive_cloneC02C2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5055
Pseudo_map_position
ReferenceWBPaper00011697
WBPaper00022302
WBPaper00038491
WBPaper00044177
WBPaper00055090
WBPaper00061115
WBPaper00065140
PictureWBPicture0000013093
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene