WormBase Tree Display for Gene: WBGene00014215
expand all nodes | collapse all nodes | view schema
| WBGene00014215 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | obr-3 | Person_evidence | WBPerson1105 | |||||
| Sequence_name | ZK1086.1 | ||||||||
| Molecular_name | ZK1086.1a | ||||||||
| ZK1086.1a.1 | |||||||||
| CE31672 | |||||||||
| ZK1086.1b | |||||||||
| CE31673 | |||||||||
| ZK1086.1b.1 | |||||||||
| Other_name | CELE_ZK1086.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | obr-3 | ||||||||
| DB_info | Database | AceView | gene | XO418 | |||||
| WormQTL | gene | WBGene00014215 | |||||||
| WormFlux | gene | WBGene00014215 | |||||||
| NDB | locus_tag | CELE_ZK1086.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00014215|UniProtKB=Q8MPR9 | |||||||
| family | PTHR10972 | ||||||||
| NCBI | gene | 181495 | |||||||
| RefSeq | protein | NM_001392877.1 | |||||||
| NM_171794.7 | |||||||||
| TREEFAM | TREEFAM_ID | TF312807 | |||||||
| TrEMBL | UniProtAcc | Q8MPR9 | |||||||
| G5EC19 | |||||||||
| UniProt_GCRP | UniProtAcc | Q8MPR9 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 02 Jul 2004 16:55:45 | WBPerson1971 | Name_change | CGC_name | obr-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | obr | ||||||||
| Allele (217) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00008832 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00012930 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00016331 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | obr-3 encodes two isoforms of a protein with an N-terminal pleckstrin domain and a C-terminal oxysterol-binding domain; OBR-3 has orthologs in Drosophila (CG5077) and humans (OSBPL8; OMIM:606736); OBR-3 binds the BMP receptor-associated molecule (BRAM) proteins BRA-1 and BRA-2; obr-3 is expressed in pharyngeal muscle, hypodermis, and several neurons; obr-3 is required for normally large body size, and the small body phenotype of obr-3(RNAi) animals is consistent with OBR-3 participating in TGF-beta signalling. | Paper_evidence | WBPaper00004823 | |||||
| WBPaper00012885 | |||||||||
| WBPaper00012937 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 08 Nov 2010 00:00:00 | ||||||||
| Automated_description | Predicted to enable cholesterol binding activity and sterol transporter activity. Involved in regulation of growth and transforming growth factor beta receptor signaling pathway. Predicted to be located in cytosol; intracellular membrane-bounded organelle; and membrane. Expressed in hypodermis; neurons; and pharyngeal muscle cell. Is an ortholog of human OSBPL5 (oxysterol binding protein like 5) and OSBPL8 (oxysterol binding protein like 8). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK1086.1a | |||||||
| ZK1086.1b | |||||||||
| Corresponding_CDS_history | ZK1086.1:wp83 | ||||||||
| Corresponding_transcript | ZK1086.1a.1 | ||||||||
| ZK1086.1b.1 | |||||||||
| Other_sequence (19) | |||||||||
| Associated_feature (15) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00021799 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00059099 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00038141 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00091933 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1629 | ||||||||
| Expr1026177 | |||||||||
| Expr1036370 | |||||||||
| Expr1162528 | |||||||||
| Expr2014593 | |||||||||
| Expr2032826 | |||||||||
| Drives_construct | WBCnstr00010358 | ||||||||
| WBCnstr00029219 | |||||||||
| Construct_product | WBCnstr00010358 | ||||||||
| WBCnstr00029219 | |||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (123) | |||||||||
| Interaction | WBInteraction000111256 | ||||||||
| WBInteraction000222018 | |||||||||
| WBInteraction000385708 | |||||||||
| WBInteraction000403215 | |||||||||
| WBInteraction000446791 | |||||||||
| WBInteraction000449697 | |||||||||
| WBInteraction000466421 | |||||||||
| WBInteraction000541283 | |||||||||
| WBInteraction000548958 | |||||||||
| Map_info | Map | X | Position | 14.9473 | Error | 0.029025 | |||
| Positive | Positive_clone | ZK1086 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4859 | |||||||
| 4827 | |||||||||
| 4961 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00010145 | ||||||||
| WBPaper00030935 | |||||||||
| WBPaper00031972 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00053705 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060493 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
