WormBase Tree Display for Gene: WBGene00014200

WBGene00014200 SMap: S_parent: Sequence: ZK1053
  Identity: Version: 3
    Name: CGC_name: scrm-2 Paper_evidence: WBPaper00029228
          Person_evidence: WBPerson1606
      Sequence_name: ZK1053.5
      Molecular_name: ZK1053.5
        ZK1053.5.1
        CE15523
      Other_name: plsc-3 Person_evidence: WBPerson1626
        CELE_ZK1053.5 Accession_evidence: NDB BX284601
      Public_name: scrm-2
    DB_info: Database: AceView gene 1N827
        WormQTL gene WBGene00014200
        WormFlux gene WBGene00014200
        NDB locus_tag CELE_ZK1053.5
        Panther gene CAEEL|WormBase=WBGene00014200|UniProtKB=G5EEQ3
          family PTHR23248
        NCBI gene 191509
        RefSeq protein NM_060920.2
        TREEFAM TREEFAM_ID TF314939
        TrEMBL UniProtAcc G5EEQ3
        UniProt_GCRP UniProtAcc G5EEQ3
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 16 Oct 2006 17:00:28 WBPerson2970 Name_change: CGC_name: plsc-3
        3 03 May 2007 10:33:07 WBPerson2970 Name_change: CGC_name: scrm-2
                Other_name: plsc-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: scrm
    Allele (21)
    Strain: WBStrain00031949
    RNASeq_FPKM (74)
    GO_annotation: 00016737
      00016738
      00016739
      00120911
      00120912
    Ortholog (38)
    Paralog: WBGene00008681 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00009753 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00011935 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00013052 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00077549 Caenorhabditis elegans From_analysis: modENCODE_Pseudogenes
      WBGene00015437 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00019531 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00019530 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00235369 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: scrm-2 encodes a putative phospholipid scramblase homologous to humanPLSCR1-5, and paralogous to other C. elegans SCRMs (e.g., SCRM-1); inapoptotic germline cells, SCRM-2 is fully dispensable for normally rapidengulfment and largely dispensable for phosphatidylserine exposure;SCRM-2 does not bind WAH-1 in vitro, and scrm-2(tm650) mutants have noobvious phenotype. Paper_evidence: WBPaper00004911
            WBPaper00012809
            WBPaper00013208
            WBPaper00013590
            WBPaper00029228
          Curator_confirmed: WBPerson567
          Date_last_updated: 16 May 2007 00:00:00
      Automated_description: Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be located in plasma membrane. Is an ortholog of several human genes including PLSCR2 (phospholipid scramblase 2); PLSCR3 (phospholipid scramblase 3); and PLSCR4 (phospholipid scramblase 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK1053.5
    Corresponding_transcript: ZK1053.5.1
    Other_sequence: Name_isotig02118
    Associated_feature: WBsf218697
      WBsf218698
      WBsf218699
  Experimental_info: RNAi_result: WBRNAi00059072 Inferred_automatically: RNAi_primary
      WBRNAi00038126 Inferred_automatically: RNAi_primary
      WBRNAi00113950 Inferred_automatically: RNAi_primary
      WBRNAi00004909 Inferred_automatically: RNAi_primary
      WBRNAi00097541 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1022312
      Expr1162502
      Expr2015651
      Expr2033883
    Drives_construct: WBCnstr00029231
    Construct_product: WBCnstr00029231
    Microarray_results (15)
    Expression_cluster (77)
    Interaction (77)
  Map_info: Map: I Position: 17.3101 Error: 0.012695
    Positive: Positive_clone: ZK1053 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Pos_neg_data: 10777
    Pseudo_map_position
  Reference: WBPaper00029228
    WBPaper00030738
    WBPaper00030766
    WBPaper00038491
    WBPaper00042257
    WBPaper00055090
    WBPaper00063045
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene