WormBase Tree Display for Gene: WBGene00014058

WBGene00014058 SMap: S_parent: Sequence: ZK673
  Identity: Version: 1
    Name: Sequence_name: ZK673.2
      Molecular_name: ZK673.2
        ZK673.2.1
        CE01714
      Other_name: CELE_ZK673.2 Accession_evidence: NDB BX284602
      Public_name: ZK673.2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (36)
    Strain: WBStrain00037810
      WBStrain00037811
    RNASeq_FPKM (74)
    GO_annotation (23)
    Contained_in_operon: CEOP2488
    Ortholog (40)
    Paralog: WBGene00002879 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00007812 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00008746 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009531 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009543 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009575 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable adenylate kinase activity and nucleoside triphosphate adenylate kinase activity. Predicted to be involved in AMP metabolic process and nucleoside triphosphate biosynthetic process. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in chronic lymphocytic leukemia and hepatocellular carcinoma. Is an ortholog of human AK3 (adenylate kinase 3) and AK4 (adenylate kinase 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:1040 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:17376)
      DOID:684 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:17376)
  Molecular_info: Corresponding_CDS: ZK673.2
    Corresponding_transcript: ZK673.2.1
    Other_sequence (26)
    Associated_feature: WBsf981264
      WBsf989352
      WBsf222015
  Experimental_info: RNAi_result: WBRNAi00059643 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1024209
      Expr1036290
      Expr1163053
      Expr2008927
      Expr2027163
    Drives_construct: WBCnstr00029344
    Construct_product: WBCnstr00029344
    Microarray_results (22)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00034761:hlh-30_downregulated
      WBPaper00035073:mitochondria_protein
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00038289:oocyte_protein
      WBPaper00040209:B.thuringiensis_upregulated_MY15
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040446:insoluble_protein
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00048988:neuron_expressed
      WBPaper00049495:starvation-refeeding_regulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051558:fog-2(q71)_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_downregulated_L1_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056165:MINA-1_interacting_mRNA
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059328:mrps-5(RNAi)_upregulated_protein
      WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
      WBPaper00059471:EGL-43_interacting
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060084:cco-1(RNAi)_upregulated_N2
      WBPaper00060871:M.humicola-infection_48h_regulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061274:microgravity_downregulated
      WBPaper00061409:neuronal-fzo-1(RNAi)_upregulated
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:cdc-42_17192-rab-5_18073
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064494:postdauer_upregulated_AWA
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_transcript
      cgc4489_group_12
      WBPaper00025032:cluster_11
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00032948:StarveUp2
      WBPaper00034739:N2moreDR1350
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_H
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040963:Q50_down
      WBPaper00040985:AIN-2_asynchronous_intestine
      WBPaper00040985:AIN-2_asynchronous_muscle
      WBPaper00040985:AIN-2_L4_intestine
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00047070:DAF-16-dependent_UV_response
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:cluster_1
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(53_min)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
    Interaction (81)
  Map_info: Positive: Positive_clone: ZK673 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: II 2.57285
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00062385
  Method: Gene