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WormBase Tree Display for Gene: WBGene00010882

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Name Class

WBGene00010882SMapS_parentSequenceCHROMOSOME_IV
IdentityVersion4
NameCGC_nameatg-7Paper_evidenceWBPaper00028973
Person_evidenceWBPerson649
Sequence_nameM7.5
Molecular_nameM7.5
M7.5.1
CE18887
Other_nameatgr-7
CELE_M7.5Accession_evidenceNDBBX284604
Public_nameatg-7
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
227 Apr 2006 11:26:11WBPerson2970Name_changeCGC_nameatgr-7
315 Mar 2007 08:29:05WBPerson2970Name_changeOther_nameatg-7
429 Feb 2008 11:29:00WBPerson2970Name_changeCGC_nameatg-7
Other_nameatgr-7
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classatg
Allele (45)
StrainWBStrain00008599
WBStrain00051662
WBStrain00051664
RNASeq_FPKM (74)
GO_annotation (22)
Contained_in_operonCEOP4404
Ortholog (39)
ParalogWBGene00000142Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004341Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006699Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006700Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006735Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00020184Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00018357Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionatg-7 encodes an E1 ubiquitin-activating-like enzyme orthologous to the autophagic budding yeast protein Apg7p; ATG-7 is required for normal dauer morphogenesis and autophagy in daf-2 mutant animals.Paper_evidenceWBPaper00006070
WBPaper00028912
WBPaper00031504
Curator_confirmedWBPerson1843
WBPerson324
WBPerson567
Date_last_updated16 Mar 2008 00:00:00
Automated_descriptionPredicted to enable Atg12 activating enzyme activity and Atg8 activating enzyme activity. Involved in several processes, including dauer larval development; determination of adult lifespan; and positive regulation of autophagosome assembly. Predicted to be located in phagophore assembly site. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 31. Is an ortholog of human ATG7 (autophagy related 7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070412Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16935)
Molecular_infoCorresponding_CDSM7.5
Corresponding_transcriptM7.5.1
Other_sequence (35)
Associated_featureWBsf652185
WBsf981819
WBsf997759
WBsf230816
Experimental_infoRNAi_result (35)
Expr_patternExpr1021948
Expr1034772
Expr1154760
Expr2009495
Expr2027732
Drives_constructWBCnstr00037850
Construct_productWBCnstr00006221
WBCnstr00006228
WBCnstr00037850
Microarray_results (20)
Expression_cluster (92)
Interaction (82)
WBProcessWBbiopr:00000003
Map_infoMapIVPosition4.82542Error0.000636
PositivePositive_cloneM7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (47)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene