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WormBase Tree Display for WBProcess: WBbiopr:00000003

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Name Class

WBbiopr:00000003Public_nameAutophagy
SummaryAutophagy is the degradation of cytoplasmic components through an autophagolysosome (autolysosome). Of the many types of autophagy in nature, macroautophagy, which involves the sequestration of cellular material by a double-membrane autophagosome, has been observed in C. elegans. The steps in this degradation process include nucleation of vesicle formation, expansion of the membrane with concomitant capture of cellular components (vesicle elongation), autophagolysosome or autolysosome, formation (autophagosome fusion with lysosome), and completion (vesicle breakdown and the lysis of the captured cytoplasmic material).
Related_topicSpecialisation_ofWBbiopr:00000052
Involved_entityGeneWBGene00018294Paper_evidenceWBPaper00006070
WBGene00006786Paper_evidenceWBPaper00031045
WBPaper00006070
WBGene00003954Paper_evidenceWBPaper00032500
WBPaper00028951
WBGene00006921Paper_evidenceWBPaper00031045
WBGene00006911Paper_evidenceWBPaper00031045
WBGene00002980Paper_evidenceWBPaper00031045
WBPaper00006070
WBPaper00041209
WBGene00010882Paper_evidenceWBPaper00006070
Interaction (37)
MoleculeWBMol:00003513Paper_evidenceWBPaper00041209
Associated_withPhenotypeWBPhenotype:0000736
GO_termGO:0006914
Reference (33)