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WormBase Tree Display for WBProcess: WBbiopr:00000003

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Name Class

WBbiopr:00000003Public_nameAutophagy
SummaryAutophagy is the degradation of cytoplasmic components through an autophagolysosome (autolysosome). Of the many types of autophagy in nature, macroautophagy, which involves the sequestration of cellular material by a double-membrane autophagosome, has been observed in C. elegans. The steps in this degradation process include nucleation of vesicle formation, expansion of the membrane with concomitant capture of cellular components (vesicle elongation), autophagolysosome or autolysosome, formation (autophagosome fusion with lysosome), and completion (vesicle breakdown and the lysis of the captured cytoplasmic material).
Related_topicSpecialisation_ofWBbiopr:00000052
Involved_entityGene (7)
Interaction (37)
MoleculeWBMol:00003513Paper_evidenceWBPaper00041209
Associated_withPhenotypeWBPhenotype:0000736
GO_termGO:0006914
Reference (33)