WormBase Tree Display for Gene: WBGene00009628

WBGene00009628 SMap: S_parent: Sequence: F42D1
  Identity: Version: 2
    Name: CGC_name: tatn-1 Person_evidence: WBPerson2977
      Sequence_name: F42D1.2
      Molecular_name: F42D1.2
        F42D1.2.1
        CE10298
      Other_name: CELE_F42D1.2 Accession_evidence: NDB BX284606
      Public_name: tatn-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:50 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 26 Nov 2009 11:16:28 WBPerson9133 Name_change: CGC_name: tatn-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tatn
    Allele (54)
    Strain: WBStrain00000172
      WBStrain00037460
    Component_of_genotype: WBGenotype00000122
      WBGenotype00000127
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (40)
    Paralog: WBGene00009232 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00010984 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00011436 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00016333 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: tatn-1 encodes a putative tyrosine aminotransferase, orthologous to human TAT (OMIM:276600, mutated in type II tyrosinemia); tatn-1 is expressed in larval and adult pharynx, hypodermis, body wall muscle, and intestine, and in adult vulval muscle and reproductive system; tatn-1 is required for the tyrosinemic phenotype of fah-1(RNAi) animals. Paper_evidence: WBPaper00006525
            WBPaper00031006
            WBPaper00031468
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 14 Dec 2009 00:00:00
      Automated_description: Predicted to enable L-tyrosine:2-oxoglutarate aminotransferase activity. Involved in dauer entry. Human ortholog(s) of this gene implicated in tyrosinemia type II. Is an ortholog of human TAT (tyrosine aminotransferase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0050725 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11573)
      DOID:9275 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11573)
  Molecular_info: Corresponding_CDS: F42D1.2
    Corresponding_transcript: F42D1.2.1
    Other_sequence (141)
    Associated_feature (11)
  Experimental_info: RNAi_result: WBRNAi00113315 Inferred_automatically: RNAi_primary
      WBRNAi00113142 Inferred_automatically: RNAi_primary
      WBRNAi00117421 Inferred_automatically: RNAi_primary
      WBRNAi00117425 Inferred_automatically: RNAi_primary
      WBRNAi00032137 Inferred_automatically: RNAi_primary
      WBRNAi00113086 Inferred_automatically: RNAi_primary
      WBRNAi00047093 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr6041
      Expr7955
      Expr11472
      Expr1016315
      Expr1034206
      Expr1150957
      Expr2017305
      Expr2035440
    Drives_construct: WBCnstr00002453
      WBCnstr00018685
      WBCnstr00032042
    Construct_product: WBCnstr00018685
      WBCnstr00020586
      WBCnstr00032042
    Regulate_expr_cluster: WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044656:tatn-1(qd182)_upregulated
    Microarray_results (17)
    Expression_cluster (221)
    Interaction: WBInteraction000029728
      WBInteraction000030333
      WBInteraction000032109
      WBInteraction000032130
      WBInteraction000122629
      WBInteraction000123199
      WBInteraction000123200
      WBInteraction000123201
      WBInteraction000123202
      WBInteraction000123203
      WBInteraction000123204
      WBInteraction000123205
      WBInteraction000123206
      WBInteraction000123207
      WBInteraction000141861
      WBInteraction000146300
      WBInteraction000155530
      WBInteraction000155531
      WBInteraction000163105
      WBInteraction000164881
      WBInteraction000170864
      WBInteraction000191542
      WBInteraction000233522
      WBInteraction000251119
      WBInteraction000251120
      WBInteraction000294860
      WBInteraction000304003
      WBInteraction000329327
      WBInteraction000334369
      WBInteraction000359863
      WBInteraction000378842
      WBInteraction000384106
      WBInteraction000384485
      WBInteraction000388463
      WBInteraction000420213
      WBInteraction000451635
      WBInteraction000460171
      WBInteraction000473571
      WBInteraction000505939
      WBInteraction000505940
      WBInteraction000506003
      WBInteraction000506004
      WBInteraction000506005
      WBInteraction000506006
      WBInteraction000506009
      WBInteraction000506010
      WBInteraction000506196
      WBInteraction000506197
      WBInteraction000506202
      WBInteraction000506203
      WBInteraction000506204
      WBInteraction000506208
      WBInteraction000506209
      WBInteraction000506210
      WBInteraction000506211
      WBInteraction000520299
      WBInteraction000520301
      WBInteraction000520303
      WBInteraction000520333
      WBInteraction000520335
      WBInteraction000521008
      WBInteraction000521009
      WBInteraction000548044
      WBInteraction000586252
      WBInteraction000586255
      WBInteraction000586258
  Map_info: Map: X Position: 21.333 Error: 0.00501
    Positive: Positive_clone: F42D1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene