WormBase Tree Display for Gene: WBGene00009051

WBGene00009051 SMap: S_parent: Sequence: F22D6
  Identity: Version: 3
    Name: CGC_name: nduf-6
      Sequence_name: F22D6.4
      Molecular_name: F22D6.4
        F22D6.4.1
        CE05685
      Other_name: ndus-6 Person_evidence: WBPerson555
        CELE_F22D6.4 Accession_evidence: NDB BX284601
      Public_name: nduf-6
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 26 Feb 2008 13:57:13 WBPerson2970 Name_change: CGC_name: nduf-6
        3 16 Jan 2023 18:37:21 WBPerson51134 Name_change: Other_name: ndus-6
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nduf
    Allele: WBVar02154164
      WBVar01499786
      WBVar01499054
      WBVar00297993
      WBVar00647630
      WBVar00647631
      WBVar00337546
      WBVar01498959
    Strain: WBStrain00049344
    RNASeq_FPKM (73)
    GO_annotation (12)
    Ortholog (36)
    Structured_description: Concise_description: F22D6.4 encodes an NDUFS6/13 kDa subunit of the mitochondrial NADH dehydrogenase (ubiquinone) complex (complex I); F22D6.4 is required for oxidative phosphorylation and for resistance to volatile anesthetics. Paper_evidence: WBPaper00005928
            WBPaper00028429
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 13 Dec 2006 00:00:00
      Automated_description: Involved in mitochondrial electron transport, NADH to ubiquinone and response to xenobiotic stimulus. Located in mitochondrion. Human ortholog(s) of this gene implicated in cervical cancer and nuclear type mitochondrial complex I deficiency 9. Is an ortholog of human NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0112073 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7713)
      DOID:4362 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7713)
  Molecular_info: Corresponding_CDS: F22D6.4
    Corresponding_transcript: F22D6.4.1
    Other_sequence (40)
    Associated_feature: WBsf643423
      WBsf981038
      WBsf217941
      WBsf217942
  Experimental_info: RNAi_result (17)
    Expr_pattern: Expr1018697
      Expr1033947
      Expr1149241
      Expr2013934
      Expr2032173
    Drives_construct: WBCnstr00032497
    Construct_product: WBCnstr00032497
    Microarray_results (20)
    Expression_cluster: WBPaper00028451:Low_abundance_spermatogenesis_enriched
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037086:biotin_regulated
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038118:aak-2(gt33)_downregulated
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040965:lipid-droplet_associated_protein
      WBPaper00044128:daf-2(e1370)_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051039:germline_enriched
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055827:pfd-6(gk493446)_upregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_protein
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059763:neuron_expressed
      WBPaper00059987:Wounding_upregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061527:C47G2.3-C47B2.9
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_downregulated_protein
      WBPaper00064992:Capsaicin_downregulated
      WBPaper00065258:anchor-cell_enriched
      cgc4386_cluster_3_5
      cgc4489_group_3
      WBPaper00025032:cluster_152
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00035504:daf-2(e1370)_upregulated
      WBPaper00036286:Pattern_G
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00049538:atfs-1(et18)_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(186_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(23_min)
      [cgc5767]:expression_class_ME
    Interaction (81)
  Map_info: Map: I Position: 1.72178 Error: 0.00283
    Positive: Positive_clone: F22D6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005928
    WBPaper00028429
    WBPaper00038491
    WBPaper00055090
    WBPaper00062388
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene