WormBase Tree Display for Gene: WBGene00008167

WBGene00008167 SMap: S_parent: Sequence: C48B4
  Identity: Version: 3
    Name: CGC_name: acox-1.5 Person_evidence: WBPerson6498
      Sequence_name: C48B4.1
      Molecular_name (3)
      Other_name: drd-51 Paper_evidence: WBPaper00044557
          Person_evidence: WBPerson10050
        acox-5 Person_evidence: WBPerson6498
        CELE_C48B4.1 Accession_evidence: NDB BX284603
      Public_name: acox-1.5
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 29 Apr 2015 12:32:17 WBPerson2970 Name_change: CGC_name: acox-5
                Other_name: drd-51
        3 05 Jan 2017 11:44:00 WBPerson2970 Name_change: CGC_name: acox-1.5
                Other_name: acox-5
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: acox
    Allele (62)
    Strain: WBStrain00032669
    RNASeq_FPKM (74)
    GO_annotation (24)
    Ortholog (39)
    Paralog (22)
    Structured_description: Automated_description: Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Involved in pheromone biosynthetic process. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0070516 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:119)
      DOID:0050797 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:119)
  Molecular_info: Corresponding_CDS: C48B4.1
    Corresponding_transcript: C48B4.1.1
    Other_sequence: BXC04384_1
      CGC01413_1
    Associated_feature: WBsf651385
      WBsf651386
      WBsf667298
      WBsf667299
      WBsf667300
      WBsf993728
      WBsf1015632
      WBsf227326
      WBsf227327
  Experimental_info: RNAi_result: WBRNAi00102608 Inferred_automatically: RNAi_primary
      WBRNAi00092601 Inferred_automatically: RNAi_primary
      WBRNAi00012089 Inferred_automatically: RNAi_primary
      WBRNAi00042707 Inferred_automatically: RNAi_primary
      WBRNAi00006132 Inferred_automatically: RNAi_primary
      WBRNAi00029928 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1024378
      Expr1033547
      Expr1146699
      Expr2009169
      Expr2027407
    Drives_construct: WBCnstr00033186
    Construct_product: WBCnstr00033186
    Microarray_results (18)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00036738:500uM_Heme_upregulated
      WBPaper00037086:biotin_regulated
      WBPaper00037624:ets-4(ok165)_downregulated
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_embryo_SelectivelyEnriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_larva_SelectivelyEnriched
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00041954:ethanol_upregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00044030:nhr-8(hd117)_upregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044557:DietaryRestriction_downregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044746:aging_downregulated_Day5
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045401:N.parisii_64h_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046509:htz-1(ok3099)_downregulated
      WBPaper00046509:lin-35(n745)_downregulated
      WBPaper00046805:P-granule-RNAi_downregulated_Set1
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00047132:glp-1(ts)-25C_upregulated_skn-1-dependent
      WBPaper00047132:skn-1(RNAi)_downregulated_glp-1(ts)-dependent
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049134:hpk-1(pk1393)_downregulated
      WBPaper00049217:TCER-1_downregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049498:npr-1(ur89)_regulated_5
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049736:15deg-then-25deg(12hr)_downregulated_N2
      WBPaper00049905:Age_variant_expression
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050080:rbr-2(tm3141)_downregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
      WBPaper00050332:daf-16(RNAi)_downregulated
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050468:hlh-30-dependent_Cry5B_regulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050928:male-mating_downregulated
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00051558:aging_regulated
      WBPaper00052868:ALA_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00052987:UV_downregulated_xpc-1;csb-1
      WBPaper00053020:sid-3(ok973)_upregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot267)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053657:N2_M.humicola-infection_12hr
      WBPaper00053664:ins-11(tm1053)_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053792:Ochrobactrum_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053814:15C_upregulated_OP50
      WBPaper00053814:OP50_vs_PY79_downregulated_PY79
      WBPaper00054758:alg-1(gk204)_downregulated
      WBPaper00054872:egl-9(sa307)_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055137:S.maltophilia_downregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055482:Tunicamycin_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056039:efa-6(tm3124)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:hpx-2(dg047)_downregulated_E.Coli
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056169:rrf-3(pk1426)_downregulated_L2
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
      WBPaper00056284:ints-2(RNAi)_downregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057265:metaformin_upregulated_OP50
      WBPaper00057347:nhr-14(tm1473)_upreglated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058665:graphene-oxide_upregulated_mRNA
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059194:klf-1(RNAi)_regulated
      WBPaper00059471:EGL-43_interacting
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059739:hira-1(gk835598)_upregulated_L4
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060764:swsn-9(ok1354)_upregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00060911:prx-5(RNAi)_upregulated_protein
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:M.braciatum_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:ASK_parent
      WBPaper00061340:BAG
      WBPaper00061340:DVC
      WBPaper00061340:Neuroblast_ADE_ADA
      WBPaper00061340:PVR
      WBPaper00061340:URX
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061466:nath-10(icb99)_downregulated
      WBPaper00061478:pie-1(ne4433)_upregulated
      WBPaper00061527:asah-1-asm-2
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061613:human-alpha-Synuclein(A53T)_downregulated
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_downregulated
      WBPaper00061853:osm-3(dh441)_upregulated
      WBPaper00061853:tunicamycin_downregulated_osm-3(dh441)
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062184:PA14_upregulated
      WBPaper00062193:daf-16(RNAi)_upregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062456:doxycycline_upregulated_CB4856_protein
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062590:Aging_upregulated_intestine
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_upregulated_protein
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064473:ets-4(rrr16)_downregulated
      WBPaper00064494:postdauer_downregulated_AWA
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00064952:Day10_vs_L4_downregulated_25C
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065392:Lb.delbrueckii_downregulated
      WBPaper00065392:Lb.gasseri_downregulated
      WBPaper00065392:Lb.reuteri_downregulated
      WBPaper00065392:P.pentosaceus_downregulated
      WBPaper00065581:hpk-1(pk1393)_downregulated
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065835:mtH2S-AP39-L1-treatment_upregulated_Day11
      WBPaper00065841:6_1
      WBPaper00065841:89_0
      WBPaper00065841:109_0
      WBPaper00065841:139_0
      WBPaper00065877:rege-1(imm070)_upregulated_OP50
      WBPaper00065877:rege-1(imm070)_upregulated_PA14
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066118:cyclobutrifluram_downregulated
      cgc4489_group_4
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00028789:PA14_vs_OP50_upregulated_4hr
      WBPaper00030985:Erwinia_carotovora_upregulated
      WBPaper00030985:Photorhabdus_luminescens_upregulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00031703:heme_responsive_7
      WBPaper00032062:age_regulated_genes
      WBPaper00032165:differentially_expressed_with_age_medoid_6
      WBPaper00032948:FedUp
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-11_regulated
      WBPaper00035873:osmotically_regulated
      WBPaper00035891:zip-2(RNAi)_downregulated
      WBPaper00036286:Pattern_G
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00037695:WC_5-day
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00038231:Cry5B_2-fold_upregulated
      WBPaper00039851:HK_C_albicans_vs_HK_OP50
      WBPaper00039851:Live_C_albicans_vs_HK_OP50
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040963:Q100_down
      WBPaper00040963:TA100_up
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.aureus_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00044535:male_downregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00045960:L1-L4-lethargus_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00046083:oga-1(ok1207)_OP50_downregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00050515:nipi-3(fr4)_upregulated
      WBPaper00055899:2,4-Dinitroanisole_regulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc6390]:Cluster_C
      [cgc6390]:herm_soma-enriched
    Interaction (29)
  Map_info: Map: III Position: 0.694396
    Positive: Positive_clone: C48B4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (14)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene