WormBase Tree Display for Gene: WBGene00008040

WBGene00008040 SMap: S_parent: Sequence: C40H1
  Identity: Version: 2
    Name: CGC_name: ttr-5
      Sequence_name: C40H1.5
      Molecular_name: C40H1.5
        C40H1.5.1
        CE00113
      Other_name: CELE_C40H1.5 Accession_evidence: NDB BX284603
      Public_name: ttr-5
    DB_info: Database: AceView gene 3K419
        WormQTL gene WBGene00008040
        WormFlux gene WBGene00008040
        NDB locus_tag CELE_C40H1.5
        Panther gene CAEEL|WormBase=WBGene00008040|UniProtKB=Q03575
          family PTHR21700
        NCBI gene 176312
        RefSeq protein NM_066653.4
        SwissProt UniProtAcc Q03575
        TREEFAM TREEFAM_ID TF315773
        UniProt_GCRP UniProtAcc Q03575
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 20 Sep 2007 11:48:01 WBPerson2970 Name_change: CGC_name: ttr-5
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ttr
    Allele: WBVar01500260
      WBVar01499774
      WBVar00849884
      WBVar00849885
      WBVar00849886
    RNASeq_FPKM (74)
    GO_annotation: 00052370
      00052371
      00052372
      00052373
      00115998
    Ortholog (37)
    Paralog (62)
    Structured_description: Concise_description: C40H1.5 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of C40H1.5 belongs to a family of apparently nematode-specific proteins whose function is not yet known. Paper_evidence: WBPaper00002969
          Curator_confirmed: WBPerson1843
          Date_last_updated: 04 Sep 2007 00:00:00
      Automated_description: Predicted to be located in cell surface and extracellular region. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C40H1.5
    Corresponding_transcript: C40H1.5.1
    Other_sequence (118)
    Associated_feature: WBsf225550
  Experimental_info: RNAi_result: WBRNAi00029711 Inferred_automatically: RNAi_primary
      WBRNAi00011820 Inferred_automatically: RNAi_primary
      WBRNAi00006140 Inferred_automatically: RNAi_primary
      WBRNAi00078581 Inferred_automatically: RNAi_primary
      WBRNAi00042261 Inferred_automatically: RNAi_primary
      WBRNAi00078622 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1026349
      Expr1033494
      Expr1146252
      Expr2017624
      Expr2035764
    Drives_construct: WBCnstr00033283
    Construct_product: WBCnstr00033283
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:Cluster_5
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:dopaminergic-neurons_larva_SelectivelyEnriched
      WBPaper00038289:oocyte_protein
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_downregulated_RNAseq
      WBPaper00040285:H2S_24hr_upregulated
      WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
      WBPaper00044005:DAF-16_upregulated
      WBPaper00044426:rotenone_5day_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045420:fertilization_upregulated_transcript
      WBPaper00045521:Spermatogenic
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00045861:ash-2(tm1095)_downregulated
      WBPaper00045861:wdr-5(ok1417)_downregulated
      WBPaper00046337:monosomal_N2_vs_daf-2_downregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_upregulated_protein
      WBPaper00046795:starvation_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048690:gonad-male-biased
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00048988:neuron_expressed
      WBPaper00049217:DAF-16_upregulated
      WBPaper00049368:daf-2(e1370)_upregulated
      WBPaper00049495:starvation-refeeding_regulated
      WBPaper00049498:npr-1(ur89)_regulated_1
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00049905:Age_variant_expression
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050053:muscle_enriched_Day12
      WBPaper00050163:let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050448:KGB-1-induced
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051404:alg-5(ram2)_upregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00052987:UV_upregulated_xpc-1;csb-1
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055827:pfd-6(gk493446)_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056218:daf-16(mu86)_upregulated_Day3
      WBPaper00056218:daf-16(mu86)_upregulated_Day5
      WBPaper00056218:daf-16(mu86)_upregulated_Day7
      WBPaper00056284:ints-6(t1903)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:spc-1(cas971)_downregulated
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060278:atp-2(RNAi)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060634:unc-120(st364)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061340:ASH
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061466:nath-10(icb102)_upregulated
      WBPaper00061527:ccg-1_12351-ZC410.5
      WBPaper00061651:ASH_enriched
      WBPaper00061699:daf-18(ok480)_downregulated
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00061952:daf-18(nr2037)_downregulated
      WBPaper00061952:daf-18(yh1)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:daf-16(RNAi)_downregulated
      WBPaper00062293:isp-1(qm150)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00064005:starvation_downregulated_N2_protein
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064788:ketamine_upregulated
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00064871:PA14_upregulated_AWA
      WBPaper00064952:Day5_vs_L4_upregulated_25C
      WBPaper00064952:Day10_vs_Day1_upregulated_25C
      WBPaper00064952:Day10_vs_Day5_upregulated_25C
      WBPaper00064952:Day10_vs_L4_upregulated_25C
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065841:4_1
      WBPaper00065841:18_0
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_3_2
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00030985:Enterococcus_faecalis_upregulated
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00032948:StarveUp2
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_D
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
      WBPaper00040426:CYE-1_CDK-2AF_downregulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040876:mir-35_downregulated
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00041207:CE_dauer_up
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041960:daf-16_fasting_upregulated
      WBPaper00041960:jun-1_fasting_upregulated
      WBPaper00041960:N2_fasting_upregulated
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042178:hlh-29(tm284)_upregulated
      WBPaper00042234:xpa-1_upregulated
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048567:dnj-14_upregulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_upregulated_AdultDay2
      WBPaper00055899:nitroguanidine_regulated
      [cgc5976]:class_1
    Interaction (177)
  Map_info: Map: III Position: 0.412782 Error: 0.003006
    Positive: Positive_clone: C40H1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00002969
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene