WormBase Tree Display for Gene: WBGene00007516
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| WBGene00007516 | SMap | S_parent | Sequence | C11E4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | gpx-5 | Person_evidence | WBPerson261 | |||||
| Sequence_name | C11E4.1 | ||||||||
| Molecular_name | C11E4.1 | ||||||||
| C11E4.1.1 | |||||||||
| CE08101 | |||||||||
| Other_name | CELE_C11E4.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | gpx-5 | ||||||||
| DB_info | Database | AceView | gene | XK203 | |||||
| WormQTL | gene | WBGene00007516 | |||||||
| WormFlux | gene | WBGene00007516 | |||||||
| NDB | locus_tag | CELE_C11E4.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00007516|UniProtKB=Q93204 | |||||||
| family | PTHR11592 | ||||||||
| NCBI | gene | 181178 | |||||||
| RefSeq | protein | NM_077214.6 | |||||||
| TREEFAM | TREEFAM_ID | TF105318 | |||||||
| TrEMBL | UniProtAcc | Q93204 | |||||||
| UniProt_GCRP | UniProtAcc | Q93204 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:48 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 20 Jul 2012 14:20:02 | WBPerson2970 | Name_change | CGC_name | gpx-5 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gpx | ||||||||
| Allele (33) | |||||||||
| Strain | WBStrain00002595 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Ortholog (55) | |||||||||
| Paralog | WBGene00009165 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00007517 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00011045 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00020373 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00022377 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00018850 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00019846 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | gpx-5 encodes a glutathione peroxidase; by homology, GPX-5 is predicted to function to reduce lipid hydroperoxides to their corresponding alcohols and reduce hydrogen peroxide to water to protect cells from damage induced by reactive oxygen species. | Curator_confirmed | WBPerson1843 | |||||
| Date_last_updated | 28 May 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable glutathione peroxidase activity. Involved in response to reactive oxygen species. Predicted to be located in extracellular space. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of human GPX3 (glutathione peroxidase 3) and GPX5 (glutathione peroxidase 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (67) | ||||||||
| Molecular_info | Corresponding_CDS | C11E4.1 | |||||||
| Corresponding_CDS_history | C11E4.1:wp83 | ||||||||
| C11E4.1:wp178 | |||||||||
| Corresponding_transcript | C11E4.1.1 | ||||||||
| Other_sequence | FG977161.1 | ||||||||
| FK805134.1 | |||||||||
| FK799871.1 | |||||||||
| MI04155 | |||||||||
| MI01069 | |||||||||
| FF681286.1 | |||||||||
| HG03103 | |||||||||
| HGC06317_1 | |||||||||
| PSC00206 | |||||||||
| GW407819.1 | |||||||||
| HBC02776_1 | |||||||||
| GR881191.1 | |||||||||
| HG06446 | |||||||||
| GR13426 | |||||||||
| MI02671 | |||||||||
| HC05812 | |||||||||
| GRC02860_1 | |||||||||
| Hbac_isotig00956 | |||||||||
| Tcol_isotig09104 | |||||||||
| GRC02612_1 | |||||||||
| FF679653.1 | |||||||||
| Name_isotig00962 | |||||||||
| GR881192.1 | |||||||||
| FK808715.1 | |||||||||
| Hbac_isotig00957 | |||||||||
| FG972476.1 | |||||||||
| FF678131.1 | |||||||||
| HS00483 | |||||||||
| AYC01502_1 | |||||||||
| MIC00259_1 | |||||||||
| MI01070 | |||||||||
| MI02670 | |||||||||
| MCC04103_1 | |||||||||
| FK802604.1 | |||||||||
| FK805808.1 | |||||||||
| Oden_isotig20592 | |||||||||
| MIC01333_1 | |||||||||
| JI225942.1 | |||||||||
| MI01887 | |||||||||
| MIC09159_1 | |||||||||
| FG977162.1 | |||||||||
| GRC00176_1 | |||||||||
| FK809643.1 | |||||||||
| MIC00259_2 | |||||||||
| FK805867.1 | |||||||||
| EX015275.1 | |||||||||
| AE03044 | |||||||||
| MA00328 | |||||||||
| HSC01091_1 | |||||||||
| HBC27149_1 | |||||||||
| CJC02368_1 | |||||||||
| PSC04819_1 | |||||||||
| GRC00590_1 | |||||||||
| GW411329.1 | |||||||||
| AW506464.1 | |||||||||
| ES672841.1 | |||||||||
| SSC00684_1 | |||||||||
| FF679631.1 | |||||||||
| FF679365.1 | |||||||||
| ACC04700_1 | |||||||||
| FK806306.1 | |||||||||
| BXC05096_1 | |||||||||
| GW410977.1 | |||||||||
| FG972428.1 | |||||||||
| CSC01946_1 | |||||||||
| Tcol_isotig09105 | |||||||||
| GW408870.1 | |||||||||
| HSC00795_1 | |||||||||
| FK804853.1 | |||||||||
| AW506553.1 | |||||||||
| MC03456 | |||||||||
| FK804291.1 | |||||||||
| HS00509 | |||||||||
| BM052020.1 | |||||||||
| GW409610.1 | |||||||||
| HSC00086_1 | |||||||||
| SS00590 | |||||||||
| FD516397.1 | |||||||||
| MAC02842_1 | |||||||||
| FK802382.1 | |||||||||
| Associated_feature | WBsf648418 | ||||||||
| WBsf663182 | |||||||||
| WBsf663183 | |||||||||
| WBsf1006478 | |||||||||
| WBsf1006479 | |||||||||
| WBsf1023593 | |||||||||
| WBsf236183 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00040349 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00091322 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00040350 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00010619 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00028806 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00115577 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00115502 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram759 | ||||||||
| Expr5242 | |||||||||
| Expr1028068 | |||||||||
| Expr1033235 | |||||||||
| Expr1144416 | |||||||||
| Expr2012219 | |||||||||
| Expr2030455 | |||||||||
| Drives_construct | WBCnstr00003154 | ||||||||
| WBCnstr00033683 | |||||||||
| Construct_product | WBCnstr00033683 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (260) | |||||||||
| Interaction | WBInteraction000114668 | ||||||||
| WBInteraction000155203 | |||||||||
| WBInteraction000519745 | |||||||||
| WBInteraction000542764 | |||||||||
| WBInteraction000552146 | |||||||||
| Map_info | Map | X | Position | 1.42294 | |||||
| Positive | Positive_clone | C11E4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00032037 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00039791 | |||||||||
| WBPaper00042257 | |||||||||
| WBPaper00042271 | |||||||||
| WBPaper00045706 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061220 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
