WormBase Tree Display for Gene: WBGene00006957
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| WBGene00006957 | Evidence | Paper_evidence | WBPaper00005843 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C07G1 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | wsp-1 | Person_evidence | WBPerson633 | |||||
| Sequence_name | C07G1.4 | ||||||||
| Molecular_name | C07G1.4a | ||||||||
| C07G1.4a.1 | |||||||||
| CE32572 | |||||||||
| C07G1.4b | |||||||||
| CE32573 | |||||||||
| C07G1.4b.1 | |||||||||
| Other_name | CELE_C07G1.4 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | wsp-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:44 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | wsp | ||||||||
| Allele (146) | |||||||||
| Strain | WBStrain00002469 | ||||||||
| WBStrain00028743 | |||||||||
| WBStrain00007551 | |||||||||
| WBStrain00007878 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (29) | |||||||||
| Contained_in_operon | CEOP4274 | ||||||||
| Ortholog (19) | |||||||||
| Paralog | WBGene00015100 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WBGene00007840 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WBGene00020094 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00015107 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | wsp-1 encodes the C. elegans WASP ortholog; when mutated, human WASP leads to Wiskott-Aldrich syndrome (OMIM:301000); wsp-1 is required for hypodermal cell migration during morphogenesis (ventral enclosure); in a yeast two-hybrid assay WSP-1 physically interacts with WIP-1, the C. elegans WASP-interacting protein ortholog; WSP-1 and WIP-1 are mutually required for normal protein levels; WSP-1 is found in migrating hypodermal cells during ventral enclosure. | Paper_evidence | WBPaper00004103 | |||||
| WBPaper00005843 | |||||||||
| WBPaper00027006 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 29 May 2013 00:00:00 | ||||||||
| Automated_description | Enables cytoskeletal regulatory protein binding activity and small GTPase binding activity. Involved in several processes, including embryonic morphogenesis; positive regulation of egg-laying behavior; and regulation of cellular component organization. Located in cell leading edge; cortical actin cytoskeleton; and presynaptic periactive zone. Expressed in Q cell; anchor cell; apoptotic cell; epithelial cell; and hypodermis. Is an ortholog of human WASL (WASP like actin nucleation promoting factor). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C07G1.4a | |||||||
| C07G1.4b | |||||||||
| Corresponding_CDS_history | C07G1.4a:wp90 | ||||||||
| C07G1.4b:wp90 | |||||||||
| Corresponding_transcript | C07G1.4a.1 | ||||||||
| C07G1.4b.1 | |||||||||
| Other_sequence (30) | |||||||||
| Associated_feature | WBsf668088 | ||||||||
| WBsf668089 | |||||||||
| WBsf668090 | |||||||||
| WBsf668091 | |||||||||
| WBsf668092 | |||||||||
| WBsf997157 | |||||||||
| WBsf997158 | |||||||||
| WBsf1017812 | |||||||||
| WBsf230394 | |||||||||
| WBsf230395 | |||||||||
| Experimental_info | RNAi_result (17) | ||||||||
| Expr_pattern (13) | |||||||||
| Drives_construct | WBCnstr00004412 | ||||||||
| WBCnstr00022478 | |||||||||
| WBCnstr00034071 | |||||||||
| Construct_product (14) | |||||||||
| Antibody | WBAntibody00000620 | ||||||||
| WBAntibody00000753 | |||||||||
| WBAntibody00000754 | |||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (105) | |||||||||
| Interaction (128) | |||||||||
| Map_info | Map | IV | Position | 3.65746 | Error | 0.002507 | |||
| Positive | Positive_clone | C07G1 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4994 | |||||||
| 5010 | |||||||||
| 4600 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (51) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
