WormBase Tree Display for Gene: WBGene00006957

WBGene00006957 Evidence: Paper_evidence: WBPaper00005843
  SMap: S_parent: Sequence: C07G1
  Identity: Version: 1
    Name: CGC_name: wsp-1 Person_evidence: WBPerson633
      Sequence_name: C07G1.4
      Molecular_name: C07G1.4a
        C07G1.4a.1
        CE32572
        C07G1.4b
        CE32573
        C07G1.4b.1
      Other_name: CELE_C07G1.4 Accession_evidence: NDB BX284604
      Public_name: wsp-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:44 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: wsp
    Allele (146)
    Strain: WBStrain00002469
      WBStrain00028743
      WBStrain00007551
      WBStrain00007878
    RNASeq_FPKM (74)
    GO_annotation (29)
    Contained_in_operon: CEOP4274
    Ortholog (19)
    Paralog: WBGene00015100 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00007840 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00020094 Caenorhabditis elegans From_analysis: Panther
      WBGene00015107 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: wsp-1 encodes the C. elegans WASP ortholog; when mutated, human WASP leads to Wiskott-Aldrich syndrome (OMIM:301000); wsp-1 is required for hypodermal cell migration during morphogenesis (ventral enclosure); in a yeast two-hybrid assay WSP-1 physically interacts with WIP-1, the C. elegans WASP-interacting protein ortholog; WSP-1 and WIP-1 are mutually required for normal protein levels; WSP-1 is found in migrating hypodermal cells during ventral enclosure. Paper_evidence: WBPaper00004103
            WBPaper00005843
            WBPaper00027006
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 29 May 2013 00:00:00
      Automated_description: Enables cytoskeletal regulatory protein binding activity and small GTPase binding activity. Involved in several processes, including embryonic morphogenesis; positive regulation of egg-laying behavior; and regulation of cellular component organization. Located in cell leading edge; cortical actin cytoskeleton; and presynaptic periactive zone. Expressed in Q cell; anchor cell; apoptotic cell; epithelial cell; and hypodermis. Is an ortholog of human WASL (WASP like actin nucleation promoting factor). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C07G1.4a
      C07G1.4b
    Corresponding_CDS_history: C07G1.4a:wp90
      C07G1.4b:wp90
    Corresponding_transcript: C07G1.4a.1
      C07G1.4b.1
    Other_sequence (30)
    Associated_feature: WBsf668088
      WBsf668089
      WBsf668090
      WBsf668091
      WBsf668092
      WBsf997157
      WBsf997158
      WBsf1017812
      WBsf230394
      WBsf230395
  Experimental_info: RNAi_result (17)
    Expr_pattern (13)
    Drives_construct: WBCnstr00004412
      WBCnstr00022478
      WBCnstr00034071
    Construct_product (14)
    Antibody: WBAntibody00000620
      WBAntibody00000753
      WBAntibody00000754
    Microarray_results (27)
    Expression_cluster (105)
    Interaction: WBInteraction000005453
      WBInteraction000005852
      WBInteraction000005857
      WBInteraction000009180
      WBInteraction000009181
      WBInteraction000033287
      WBInteraction000033443
      WBInteraction000033553
      WBInteraction000033687
      WBInteraction000033689
      WBInteraction000033690
      WBInteraction000034538
      WBInteraction000034830
      WBInteraction000035000
      WBInteraction000035001
      WBInteraction000035038
      WBInteraction000035461
      WBInteraction000035462
      WBInteraction000035463
      WBInteraction000035464
      WBInteraction000035615
      WBInteraction000036038
      WBInteraction000036065
      WBInteraction000036956
      WBInteraction000037274
      WBInteraction000037275
      WBInteraction000037276
      WBInteraction000037277
      WBInteraction000037826
      WBInteraction000038991
      WBInteraction000038992
      WBInteraction000039630
      WBInteraction000040251
      WBInteraction000040252
      WBInteraction000040253
      WBInteraction000040254
      WBInteraction000041315
      WBInteraction000041833
      WBInteraction000043141
      WBInteraction000045712
      WBInteraction000045713
      WBInteraction000051385
      WBInteraction000051386
      WBInteraction000051765
      WBInteraction000051766
      WBInteraction000135631
      WBInteraction000135632
      WBInteraction000135633
      WBInteraction000135634
      WBInteraction000135635
      WBInteraction000135636
      WBInteraction000135637
      WBInteraction000145313
      WBInteraction000149440
      WBInteraction000149573
      WBInteraction000149905
      WBInteraction000150516
      WBInteraction000156677
      WBInteraction000157261
      WBInteraction000158968
      WBInteraction000159818
      WBInteraction000159819
      WBInteraction000160725
      WBInteraction000164455
      WBInteraction000165260
      WBInteraction000167699
      WBInteraction000167700
      WBInteraction000167701
      WBInteraction000169802
      WBInteraction000173441
      WBInteraction000174046
      WBInteraction000174047
      WBInteraction000174048
      WBInteraction000174049
      WBInteraction000174050
      WBInteraction000174051
      WBInteraction000174052
      WBInteraction000174053
      WBInteraction000188624
      WBInteraction000237529
      WBInteraction000258484
      WBInteraction000262796
      WBInteraction000276263
      WBInteraction000339825
      WBInteraction000361755
      WBInteraction000501877
      WBInteraction000501878
      WBInteraction000501879
      WBInteraction000502293
      WBInteraction000502294
      WBInteraction000523688
      WBInteraction000523713
      WBInteraction000523755
      WBInteraction000523764
      WBInteraction000538847
      WBInteraction000538848
      WBInteraction000540210
      WBInteraction000541294
      WBInteraction000542389
      WBInteraction000545910
      WBInteraction000545989
      WBInteraction000546209
      WBInteraction000546235
      WBInteraction000546394
      WBInteraction000546464
      WBInteraction000546616
      WBInteraction000546652
      WBInteraction000546758
      WBInteraction000546823
      WBInteraction000546893
      WBInteraction000550413
      WBInteraction000550414
      WBInteraction000550415
      WBInteraction000550416
      WBInteraction000550417
      WBInteraction000550418
      WBInteraction000555741
      WBInteraction000555742
      WBInteraction000556031
      WBInteraction000556265
      WBInteraction000556735
      WBInteraction000556736
      WBInteraction000556737
      WBInteraction000556738
      WBInteraction000556739
      WBInteraction000556740
      WBInteraction000561285
      WBInteraction000577271
  Map_info: Map: IV Position: 3.65746 Error: 0.002507
    Positive: Positive_clone: C07G1 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4994
        5010
        4600
    Pseudo_map_position
  Reference (51)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene